Insertion in the first exon, 5bp downstream of the first ATG codon.
Insertion within the first exon, 539bp upstream of the ATG start codon.
Defects in autophagosome formation in starved Atg1EP3348 homozygous larvae are not rescued in a S6k07084 or S6kl-1 heterozygous background. However, eclosion rates are increased in these animals in a dose-dependent manner. Roughly 50% of Atg1EP3348, S6k07084/+ eclose, increased to 70% in a Atg1EP3348, S6kl-1/+ genetic background.
Tork17004 homozygous animals in a heterozygous Atg1EP3348 genetic background grow faster, and extend their developmental stage to mid/late third instar larval stage. Double homozygous animals survive to mid-late third instar larval stage.