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General Information
Symbol
Dmel\taraL4
Species
D. melanogaster
Name
FlyBase ID
FBal0135608
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

P{lacW} insertion in an intron.

Insertion components
P{lacW}taraL4
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes and taraL4/Df(3R)sbd26 animals die as late embryos or first instar larvae without any obvious cuticle pattern defects. Heterozygotes do not have a held-out wing phenotype. taraL4 homozygotes rescued by one copy of taraβ.Ubi-p63E have poor fertility and a fully penetrant wings-held-out phenotype. taraL4 homozygotes rescued by a single copy of taraβ.Ubi-p63E sometimes have a thickened arista (resembling a weak antenna-to-leg transformation) and they may have haltere defects, which appear to be result from transformation to wing margin (a row of bristles is formed). Only 30% of taraL4 homozygotes rescued by two copies of taraβ.Ubi-p63E have a held-out wings phenotype and their fertility is increased compared to those carrying one copy of taraβ.Ubi-p63E.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

brm[+]/brm2, taraL4 has visible | dominant phenotype, enhanceable by trx[+]/trxE2

Suppressor of
Statement
Reference

taraL4 is a suppressor of visible | dominant | homeotic phenotype of ph-p410

taraL4 is a suppressor of visible | dominant | homeotic phenotype of Pc16

Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

brm[+]/brm2, taraL4 has wing phenotype, enhanceable by trx[+]/trxE2

Suppressor of
Statement
Reference

taraL4 is a suppressor of mesothoracic leg phenotype of ph-p410

taraL4 is a suppressor of metathoracic leg phenotype of ph-p410

taraL4 is a suppressor of sex comb | ectopic phenotype of ph-p410

taraL4 is a suppressor of mesothoracic leg phenotype of Pc16

taraL4 is a suppressor of metathoracic leg phenotype of Pc16

taraL4 is a suppressor of sex comb | ectopic phenotype of Pc16

NOT Suppressor of
Statement
Reference

taraL4/tara[+] is a non-suppressor of eye phenotype of Scer\GAL4ey.PH, asf1UAS.cMa

Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

60% of flies carrying pbhs.PB that are also heterozygous for taraL4 show partial truncation of the distal part of wing vein L4. This phenotype is not seen in either pbhs.PB single mutant or taraL4/+ single mutant flies. Deletions of wing vein L5 are also seen in the double mutant flies. pb4 taraL4/pb13 + flies show a weak but reliable transformation of the distal labium to antennal arista. 36% of osa1 taraL4 double heterozygotes have a held-out wing phenotype. 2% of trxE2 taraL4 double heterozygotes have a held-out wing phenotype. 12% of brm2 taraL4 double heterozygotes have a held-out wing phenotype. 45% of trxE2 brm2 taraL4 triple heterozygotes have a held-out wing phenotype.

taraL4/+ does not suppress the rough eye phenotype due to Scer\GAL4ey.PH; asf1Scer\UAS.cMa.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescued by
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

The recessive lethality of taraL4 and its interaction with pbhs.PB can be reverted by excision of the P{lacW} element.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
taraL4
Name Synonyms
Secondary FlyBase IDs
    References (2)