A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Allele Scer\GAL4αTub84B.PK

General Information
SymbolScer\GAL4αTub84B.PKSpeciesS. cerevisiae
NameFlyBase IDFBal0135814
Feature typealleleCreated / Updated2006-08-20/2006-08-20
Associated geneScer\GAL4
Allele class
Mutagenin vitro construct | regulatory fusion
hide Nature of the Allele
Allele class
Mutagen
in vitro construct | regulatory fusion
(Kramps et al., 2002)
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
      Construct: The FRT cassette has been excised, causing the αTub84B promoter sequences to be positioned just upstream and in control of Scer\GAL4.
      (Kramps et al., 2002)
      Assay mode
      In transgenic Drosophila (allele of foreign species in genome of drosophilid)
      (Kramps et al., 2002)
      Carried in construct
      P{tubP-GAL4}
      (Hughes and Fehon, 2006, Guelman et al., 2006, Papaconstantinou et al., 2005, Seto and Bellen, 2006, Lichtneckert et al., 2007, Romero-Pozuelo et al., 2007)
      Cytology
      hide Phenotypic Data
      hide Phenotypic Class
      lethal | embryonic stage | conditional - heat sensitive, with Mnn1Scer\UAS.cPa
      (Papaconstantinou et al., 2005)
      lethal | embryonic stage | conditional - heat sensitive, with Mnn1dsRNA.Scer\UAS
      (Papaconstantinou et al., 2005)
      lethal, with dsΔECD.Scer\UAS, ds05142
      (Matakatsu and Blair, 2006)
      lethal, with dsΔECD.Scer\UAS/ds05142
      (Matakatsu and Blair, 2006)
      environmental stress response defective, with Mnn1Scer\UAS.cPa
      (Papaconstantinou et al., 2005)
      environmental stress response defective, with Mnn1dsRNA.Scer\UAS
      (Papaconstantinou et al., 2005)
      chemical sensitive, with Mnn1Scer\UAS.cPa
      (Papaconstantinou et al., 2005)
      hide Phenotype Manifest In
      embryonic/first instar larval cuticle, with armS10.Scer\UAS.T:Hsap\MYC
      (Kramps et al., 2002)
      wing, with dsScer\UAS.cTa
      (Matakatsu and Blair, 2006)
      wing, with dsΔECD.Scer\UAS
      (Matakatsu and Blair, 2006)
      wing, with dsΔICD.Scer\UAS
      (Matakatsu and Blair, 2006)
      hide Detailed Description
      Statement
      Reference
      hide Interactions
      hide Phenotypic Class
      hideSuppressor of
      Statement
      Reference
      Scer\GAL4αTub84B.PK/BacA\p35Scer\UAS.cHa is a suppressor of cell death increase | somatic clone phenotype of ems3
      (Lichtneckert et al., 2007)
      hide Phenotype Manifest In
      hideSuppressed by
      Statement
      Reference
      Scer\GAL4αTub84B.PK, armS10.Scer\UAS.T:Hsap\MYC has embryonic/first instar larval cuticle phenotype, suppressible by lgsunspecified
      (Kramps et al., 2002)
      hideSuppressor of
      Statement
      Reference
      Scer\GAL4αTub84B.PK/BacA\p35Scer\UAS.cHa is a suppressor of neuroblast | somatic clone phenotype of ems3
      (Lichtneckert et al., 2007)
      hide Additional Comments
      hide Genetic Interactions
      Statement
      Reference
      hide Xenogenetic Interactions
      Statement
      Reference
      hide Complementation & Rescue Data
      Rescues
      Scer\GAL4αTub84B.PK/wdaScer\UAS.cGa rescues wda3
      (Guelman et al., 2006)
      emsScer\UAS.cRa/Scer\GAL4αTub84B.PK rescues ems3
      (Lichtneckert et al., 2007)
      Partially rescues
      Scer\GAL4αTub84B.PK/dsScer\UAS.cTa partially rescues ds05142
      (Matakatsu and Blair, 2006)
      dsΔICD.Scer\UAS/Scer\GAL4αTub84B.PK partially rescues ds05142
      (Matakatsu and Blair, 2006)
      Comments
      hide Stocks ( 2 )
      Bloomington
      5138
      y1 w*; P{tubP-GAL4}LL7/TM3, Sb1
      5143
      w*; P{FRT(whs)}G13, P{πM}45F, P{tubP-GAL80}LL2/SM6a; P{tubP-GAL4}LL7/TM6B, Tb1
      hide Notes on Origin
      Discoverer
      hide Synonyms & Secondary IDs ( 1 )
      Reported As
      Symbol Synonym
      Scer\GAL4αTub84B.PK
       
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 9 )
        Research paper
        Lichtneckert et al., 2007, Development 134(7): 1291--1300
        Cell lineage-specific expression and function of the empty spiracles gene in adult brain development of Drosophila melanogaster. [FBrf0192514]
        Romero-Pozuelo et al., 2007, Europ. J. Neurosci. 26(9): 2428--2443
        Chronic and acute alterations in the functional levels of Frequenins 1 and 2 reveal their roles in synaptic transmission and axon terminal morphology. [FBrf0200597]
        Guelman et al., 2006, Molec. Cell. Biol. 26(19): 7178--7189
        The essential gene wda encodes a WD40 repeat subunit of Drosophila SAGA required for histone H3 acetylation. [FBrf0192338]
        Hughes and Fehon, 2006, J. Cell Biol. 175(2): 305--313
        Phosphorylation and activity of the tumor suppressor Merlin and the ERM protein Moesin are coordinately regulated by the Slik kinase. [FBrf0193095]
        Matakatsu and Blair, 2006, Development 133(12): 2315--2324
        Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins. [FBrf0194700]
        Seto and Bellen, 2006, J. Cell Biol. 173(1): 95--106
        Internalization is required for proper Wingless signaling in Drosophila melanogaster. [FBrf0190944]
        Papaconstantinou et al., 2005, Molec. Cell. Biol. 25(22): 9960--9972
        Menin is a regulator of the stress response in Drosophila melanogaster. [FBrf0191201]
        Townsley et al., 2004, Nature Cell Biol. 6(7): 626--633
        Pygopus and Legless target Armadillo/beta-catenin to the nucleus to enable its transcriptional co-activator function. [FBrf0179484]
        Kramps et al., 2002, Cell 109(1): 47--60
        Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. [FBrf0146918]