FlyBase Allele Report: Dmel\lap[EP3060]

General Information

Symbol

Dmel\lap^EP3060

Species

D. melanogaster

Name

FlyBase ID

FBal0136059

Feature type

allele

Associated gene

Dmel\lap

Associated Insertion(s)

P{EP}lap^EP3060

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Pena-Rangel et al., 2002)

Progenitor genotype

Associated Insertion(s)

P{EP}lap^EP3060

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:7,186,983..7,186,983 [+]

(Sun et al., 2006, Pena-Rangel et al., 2002)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^GMR.PF

(Sun et al., 2006)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PF

(Sun et al., 2006)

ommatidium, with Scer\GAL4^GMR.PF

(Sun et al., 2006)

Detailed Description

Statement

Reference

Expression of lap^EP3060 under the control of Scer\GAL4^GMR.PF results in a mild rough eye phenotype with no loss of pigmentation.

(Sun et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, enhanceable by D1^EP473, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, enhanceable by BicDR^EP3705, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, enhanceable by jing^UAS.cSa/Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, enhanceable by nuf^EP3339/Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, enhanceable by EP3303^EP3303, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, enhanceable by cnc^EP3258/Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, enhanceable by EP3377^EP3377, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, enhanceable by Atx2^EP3145, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, enhanceable by XNP^EP635/Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, enhanceable by Scer\GAL4^GMR.PF/jigr1^EP3354

(Sun et al., 2006)

NOT Enhanced by

Statement

Reference

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, non-enhanceable by EP3916^EP3916, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, non-enhanceable by EP893^EP893, Scer\GAL4^GMR.PF

(Sun et al., 2006)

NOT suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, non-suppressible by EP3916^EP3916, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has visible phenotype, non-suppressible by EP893^EP893, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Enhancer of

Statement

Reference

lap^EP3060, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of H^UAS.cMa, Scer\GAL4^GMR.PF

(Müller et al., 2005)

Scer\GAL4^pnr-MD237/lap^EP3060 is an enhancer of visible phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

NOT Enhancer of

Statement

Reference

lap^EP3060/Scer\GAL4^GMR.PF is a non-enhancer of visible phenotype of Scer\GAL4^GMR.PF, kay^EP3084

(Sun et al., 2006)

NOT Suppressor of

Statement

Reference

lap^EP3060/Scer\GAL4^GMR.PF is a non-suppressor of visible phenotype of Scer\GAL4^GMR.PF, kay^EP3084

(Sun et al., 2006)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^GMR.PF, lap^EP3060 has ommatidium phenotype, enhanceable by D1^EP473, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, enhanceable by BicDR^EP3705, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has ommatidium phenotype, enhanceable by BicDR^EP3705, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, enhanceable by jing^UAS.cSa/Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has ommatidium phenotype, enhanceable by jing^UAS.cSa/Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, enhanceable by nuf^EP3339/Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, enhanceable by Atx2^EP3145, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, enhanceable by EP3303^EP3303, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, enhanceable by cnc^EP3258/Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, enhanceable by EP3377^EP3377, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, enhanceable by XNP^EP635/Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, enhanceable by Scer\GAL4^GMR.PF/jigr1^EP3354

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has ommatidium phenotype, enhanceable by Scer\GAL4^GMR.PF/jigr1^EP3354

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, enhanceable by D1^EP473, Scer\GAL4^GMR.PF

(Sun et al., 2006)

NOT Enhanced by

Statement

Reference

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, non-enhanceable by EP3916^EP3916, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, non-enhanceable by EP893^EP893, Scer\GAL4^GMR.PF

(Sun et al., 2006)

NOT suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, non-suppressible by EP3916^EP3916, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Scer\GAL4^GMR.PF, lap^EP3060 has eye phenotype, non-suppressible by EP893^EP893, Scer\GAL4^GMR.PF

(Sun et al., 2006)

Enhancer of

Statement

Reference

lap^EP3060, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of H^UAS.cMa, Scer\GAL4^GMR.PF

(Müller et al., 2005)

NOT Enhancer of

Statement

Reference

lap^EP3060/Scer\GAL4^GMR.PF is a non-enhancer of eye phenotype of Scer\GAL4^GMR.PF, kay^EP3084

(Sun et al., 2006)

NOT Suppressor of

Statement

Reference

lap^EP3060/Scer\GAL4^GMR.PF is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PF, kay^EP3084

(Sun et al., 2006)

Other

Statement

Reference

Atx2^EP3145, Scer\GAL4^GMR.PF, lap^EP3060 has pigment cell phenotype

(Sun et al., 2006)

Scer\GAL4^GMR.PF, XNP^EP635, lap^EP3060 has pigment cell phenotype

(Sun et al., 2006)

Scer\GAL4^GMR.PF, jing^UAS.cSa, lap^EP3060 has pigment cell phenotype

(Sun et al., 2006)

Scer\GAL4^pnr-MD237, lap^EP3060, pnr^MD237 has scutellum phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, lap^EP3060, pnr^MD237/pnr[+] has scutellum phenotype

(Pena-Rangel et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of jing^Scer\UAS.cSa enhances the severity of the rough eye phenotype caused by expression of lap^EP3060 under the control of Scer\GAL4^GMR.PF and in addition, loss of pigmentation in the eye is seen.

(Sun et al., 2006)

pnr^MD237/+ adults expressing EP3060^EP3060 under the control of Scer\GAL4^pnr-MD237 have a reduced scutellum.

(Pena-Rangel et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

EP3060^EP3060

lap^EP3060

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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