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General Information
Symbol
Dmel\obk1
Species
D. melanogaster
Name
FlyBase ID
FBal0137133
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    obk1 expressivity is affected by natural variation as shown by comparison in the background of eight distinct newly isolated wild caught third chromosomes. In addition arista number decreases with larval density.

    Mutants show a duplicated second, third and sixth/arista antennal segments. The effect varies and may not affect all segments. Sometimes triplications occur. Maxillary structures may be duplicated or absent, eyes may be reduced and bristles on the face may be abnormal.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Enhanced by
    Statement
    Reference

    obk1 has arista | increased number phenotype, enhanceable by Hsp83e6D/Hsp83[+]

    Suppressed by
    Statement
    Reference

    obk1 has arista | increased number phenotype, suppressible by l(2)gd1d7

    obk1 has arista | increased number phenotype, suppressible by wgl-16

    obk1 has arista | increased number phenotype, suppressible by wgl-17

    obk1 has arista | increased number phenotype, suppressible by dppd12

    obk1 has arista | increased number phenotype, suppressible by Hsp8308445/Hsp83[+]

    obk1 has arista | increased number phenotype, suppressible by Hsp8319F2/Hsp83[+]

    obk1 has arista | increased number phenotype, suppressible by Hsp83P582/Hsp83[+]

    obk1 has arista | increased number phenotype, suppressible by Hsp83j5C2/Hsp83[+]

    obk1 has arista | increased number phenotype, suppressible by exbrl

    obk1 has arista | increased number phenotype, suppressible by ft4

    obk1 has arista | increased number phenotype, suppressible by ft8

    obk1 has arista | increased number phenotype, suppressible by hyd15

    NOT suppressed by
    Statement
    Reference

    obk1 has arista | increased number phenotype, non-suppressible by dppd5

    obk1 has arista | increased number phenotype, non-suppressible by wgl-8

    Other
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    obk1, Antp73b (or AntpNs), hthdtl-S142204 triple mutants produce biramous antenna/legs in place of single antennae. Biramous appendages also appear in obk1, ssa combinations. obk1, Antphs.PHTA produces bi- or polyramous appendages with both antenna and leg combinations after heat shocks of 40 min duration at either 56 or 60 hours after hatch.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    Comments
    Comments

    Partially complements: enE. enE fails to complement the wing venation defects of obk1 but complements the antennal duplciation and eye bristle phenotype.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    obk1
    Name Synonyms
    Secondary FlyBase IDs
      References (2)