Allele Scer\GAL4¹¹¹⁸

General Information
Symbol	Scer\GAL4¹¹¹⁸	Species	S. cerevisiae
Name		FlyBase ID	FBal0137380
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{GAL4}1118 (Malpel et al., 2002, Grima et al., 2002, Dissel et al., 2004, Blanchardon et al., 2001, Sathyanarayanan et al., 2004, Morante and Desplan, 2008, Lear et al., 2005, Chen et al., 2011, Lamaze et al., 2011)
Cytology
Phenotypic Data
Phenotypic Class
	circadian rhythm defective, with slmb^Scer\UAS.cGa (Grima et al., 2002) circadian rhythm defective \| dominant (Blanchardon et al., 2001) locomotor rhythm defective, with Ctet\TeTxLC^TNT.Scer\UAS (Blanchardon et al., 2001) locomotor rhythm defective, with Cul-3^{K717R.Scer\UAS.T:Avic\GFP} (Grima et al., 2012) locomotor rhythm defective, with Cul-3^NIG.11861R (Grima et al., 2012) locomotor rhythm defective, with cwo^{dsRNA.IR.Scer\UAS} (Matsumoto et al., 2007) locomotor rhythm defective, with Mmus\Bax^Scer\UAS.cGa (Blanchardon et al., 2001) locomotor rhythm defective, with per^Scer\UAS.cBa (Blanchardon et al., 2001) partially lethal - majority die \| embryonic stage, with Mmus\Bax^Scer\UAS.cGa (Blanchardon et al., 2001)
Phenotype Manifest In
	wing, with Mmus\Bax^Scer\UAS.cGa (Blanchardon et al., 2001)
Detailed Description
	Statement Reference Flies carrying one or two copies of Scer\GAL4[1118] insertion display a 1-h lengthening of their circadian period. The period change is lost upon excision of P{GAL4}1118. (Blanchardon et al., 2001)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	slmb^Scer\UAS.cGa/Scer\GAL4¹¹¹⁸ rescues slmb⁸/slmb^L.hs (Grima et al., 2002)
Fails to rescue	Scer\GAL4¹¹¹⁸/na^Scer\UAS.cLa fails to rescue na^har (Lear et al., 2005)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	gal1118 (Grima et al., 2012) gal¹¹¹⁸ (Matsumoto et al., 2007) Scer\GAL4¹¹¹⁸
Name Synonym
Secondary FlyBase IDs

References ( 11 )
Research paper	Grima et al., 2012, PLoS Biol. 10(8): e1001367 CULLIN-3 Controls TIMELESS Oscillations in the Drosophila Circadian Clock. [FBrf0219137] Chen et al., 2011, Curr. Biol. 21(9): 719--729 QUASIMODO, a Novel GPI-Anchored Zona Pellucida Protein Involved in Light Input to the Drosophila Circadian Clock. [FBrf0213611] Lamaze et al., 2011, EMBO Rep. 12(6): 549--557 The E3 ubiquitin ligase CTRIP controls CLOCK levels and PERIOD oscillations in Drosophila. [FBrf0213851] Morante and Desplan, 2008, Curr. Biol. 18(8): 553--565 The color-vision circuit in the medulla of Drosophila. [FBrf0204652] Matsumoto et al., 2007, Genes Dev. 21(13): 1687--1700 A functional genomics strategy reveals clockwork orange as a transcriptional regulator in the Drosophila circadian clock. [FBrf0201156] Lear et al., 2005, Neuron 48(6): 965--976 The ion channel narrow abdomen is critical for neural output of the Drosophila circadian pacemaker. [FBrf0191323] Dissel et al., 2004, Nat. Neurosci. 7(8): 834--840 A constitutively active cryptochrome in Drosophila melanogaster. [FBrf0179188] Sathyanarayanan et al., 2004, Cell 116(4): 603--615 Posttranslational regulation of Drosophila PERIOD protein by protein phosphatase 2A. [FBrf0174437] Grima et al., 2002, Nature 420(6912): 178--182 The F-box protein Slimb controls the levels of clock proteins Period and Timeless. [FBrf0152243] Malpel et al., 2002, Development 129(6): 1443--1453 Larval optic nerve and adult extra-retinal photoreceptors sequentially associate with clock neurons during Drosophila brain development. [FBrf0144829] Blanchardon et al., 2001, Europ. J. Neurosci. 13(5): 871--888 Defining the role of Drosophila lateral neurons in the control of circadian rhythms in motor activity and eclosion by targeted genetic ablation and PERIOD protein overexpression. [FBrf0134606]

Allele Scer\GAL41118

Allele Scer\GAL4¹¹¹⁸