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General Information
Symbol
Dmel\Penk14401a
Species
D. melanogaster
Name
FlyBase ID
FBal0137395
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Insertion of a P{lacW} element in the 5' untranslated region of Pen.

Insertion components
P{lacW}Penk14401a
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Penk14401a heterozygous flies (genetic background = Canton-S) have a significantly decreased geotaxis score compared to wild-type (Canton-S) flies.

Penk14401a homozygotes are wild type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (3)
Notes on Origin
Discoverer

Separable from: oho31k14401b. The larval lethality and overgrowth of hematopoietic tissue phenotypes originally described as being due to Penk14401a in FBrf0082252 and FBrf0082712 have been found to be due to a second site mutation (oho31k14401b).

Comments
Comments

The mutant phenotypes of "l(2)k14401" homozygotes (which carry both oho31k14401b and P{lacW}Penk14401a) described in FBrf0082712 and FBrf0082252 are all due to the oho31k14401b mutation and are not due to the P{lacW}Penk14401a insertion.

FlyBase curator comment: "oho31" phenotype (overgrown hematopoietic tissues and larval lethality) in the "l(2)k14401" insertion line is stated in FBrf0082252 to be due to an effect on the "Pen" gene, however, FBrf0149010 states that the "oho31" mutant phenotype is caused by a second site mutation separable from the insertion in "Pen" in the "l(2)k14401" insertion line.

FlyBase curator comment: "oho31" phenotype (overgrown hematopoietic tissues and larval lethality) in the "l(2)k14401" insertion line is stated in FBrf0082712 to be due to an effect on the "Pen" gene, however, FBrf0149010 states that the "oho31" mutant phenotype is caused by a second site mutation separable from the insertion in "Pen" in the "l(2)k14401" insertion line.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (7)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
  • FBal0035094
References (10)