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General Information
Symbol
Dmel\Ilp2hs.PR
Species
D. melanogaster
Name
heat shock construct of Rulifson
FlyBase ID
FBal0137484
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
hs-dilp2
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A heat shock promoter drives expression of Ilp2 EST GH11579.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Ilp2hs.PR using heat shock results in an increase in pupal length compared to wild type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhanced by
Statement
Reference

Ilp2hs.PR has large body | heat sensitive phenotype, non-enhanceable by Nf1E2

NOT suppressed by
Statement
Reference

Ilp2hs.PR has large body | heat sensitive phenotype, non-suppressible by Nf1E2

Suppressor of
Phenotype Manifest In
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Nf1E2 has no effect on in the increased pupal length phenotype caused by expression of Ilp2hs.PR using heat shock.

Females in which insulin-like peptide (ILP)-producing brain cells have been ablated (by expression of rprScer\UAS.C under the control of Scer\GAL4Ilp2.PR) and which also express Ilp2hs.PR during larval development (to rescue developmental defects caused by the ablation of the ILP-producing brain cells) still show a reduced follicle cell proliferation rate in response to a protein-rich diet.

The size of larvae expressing rprScer\UAS.C under the control of Scer\GAL4Ilp2.PR at 120 hours of development is rescued to 88% of normal by expression of Ilp2hs.PR. The wing growth defects are also rescued. The developmental time to reach wandering third instar and puparium formation is approximately 6 days in these rescued larvae, compared to 5 days in wild type.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
IRPhs.PR
Ilp2hs.PR
Name Synonyms
heat shock construct of Rulifson
Secondary FlyBase IDs
    References (5)