Allele Dmel\Arp1^dsRNA.cEa

General Information
Symbol	Dmel\Arp1^dsRNA.cEa	Species	D. melanogaster
Name		FlyBase ID	FBal0137659
Feature type	allele	Associated gene	Dmel\Arp1

Allele class
Mutagen	in vitro construct - RNAi
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - RNAi (Eaton et al., 2002)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Templates consists of a 595 bp region corresponding to exon 5 of the predicted Arp87C gene. (Eaton et al., 2002)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In
	synapse (Eaton et al., 2002)
Detailed Description
	Statement Reference When Arp87C is inhibited in Arp87C^dsRNA.cEa late embryos, the number of synaptic fingerprints (seen after synapses retract) at the synapse on muscles 6 and 7 is significantly increased (30.6% of synapses) compared to controls (6-7% of synapses), suggesting a reduction in synaptic stability at the neuromuscular junction. (Eaton et al., 2002)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	dsRNA has been synthesised and soaked into late embryos to study the phenotypic consequences of dsRNA interference (RNAi) of the Arp87C gene. (Eaton et al., 2002)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Arp1^dsRNA.cEa Arp87C^dsRNA.cEa
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Eaton et al., 2002, Neuron 34(5): 729--741 Dynactin is necessary for synapse stabilization. [FBrf0149140]

Allele Dmel\Arp1dsRNA.cEa

Allele Dmel\Arp1^dsRNA.cEa