Allele Dmel\pUf68⁹

General Information
Symbol	Dmel\pUf68⁹	Species	D. melanogaster
Name		FlyBase ID	FBal0138184
Feature type	allele	Associated gene	Dmel\pUf68
Also Known As	hfp⁹

Allele class	hypomorphic allele - genetic evidence
Mutagen	P-element activity
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class	hypomorphic allele - genetic evidence (Van Buskirk and Schupbach, 2002)
Mutagen	P-element activity (Van Buskirk and Schupbach, 2002)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	pUf68^EP3058 (Van Buskirk and Schupbach, 2002)
Nature of the lesion	Statement Reference Internal deletion of the P{EP} element, with 481bp of the element remaining. (Van Buskirk and Schupbach, 2002)
Caused by insertion	P{EP-Δ9}pUf68⁹ (Van Buskirk and Schupbach, 2002)
Cytology
Phenotypic Data
Phenotypic Class
	female sterile \| recessive (Van Buskirk and Schupbach, 2002) lethal (with Df(3L)Ar14-8) (Van Buskirk and Schupbach, 2002) male sterile \| recessive (Van Buskirk and Schupbach, 2002)
Phenotype Manifest In
	dorsal appendage (Van Buskirk and Schupbach, 2002) egg (Van Buskirk and Schupbach, 2002) egg chamber (Van Buskirk and Schupbach, 2002) karyosome (Van Buskirk and Schupbach, 2002) nurse cell & nuclear chromosome (Van Buskirk and Schupbach, 2002)
Detailed Description
	Statement Reference 24% of homozygous egg chambers contain only eight germline cells at room temperature. 96% of egg chambers have polytene nuclei and the karyosome appears abnormally shaped, diffuse or fragmented in 15.3% of egg chambers. Homozygous females lay few eggs, which are shorter than normal and have dorsal-ventral polarity defects (ranging from dorsalised with a ring of dorsal appendage material through to partially ventralised with a single dorsal appendage). (Van Buskirk and Schupbach, 2002)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement Reference pUf68⁹ has egg chamber phenotype, suppressible by otu¹⁰⁴ (Van Buskirk and Schupbach, 2002) pUf68⁹ has karyosome phenotype, suppressible by otu¹⁰⁴ (Van Buskirk and Schupbach, 2002) pUf68⁹ has nurse cell & nuclear chromosome phenotype, suppressible by otu¹⁰⁴ (Van Buskirk and Schupbach, 2002)
Additional Comments
Genetic Interactions
Statement Reference otu¹⁰⁴ rescues the nurse cell and oocyte nuclear morphology and germline division defects of pUf68⁹ mutant females. (Van Buskirk and Schupbach, 2002)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescued by	pUf68⁹ is rescued by pUf68^{otu.T:Avic\GFP} (Van Buskirk and Schupbach, 2002)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	hfp⁹ (Goodrich et al., 2004, Van Buskirk and Schupbach, 2002) pUf68⁹
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Goodrich et al., 2004, Development 131(9): 1949--1958 Hrb27C, Sqd and Otu cooperatively regulate gurken RNA localization and mediate nurse cell chromosome dispersion in Drosophila oogenesis. [FBrf0174571] Van Buskirk and Schupbach, 2002, Dev. Cell 2(3): 343--353 half pint regulates alternative splice site selection in Drosophila. [FBrf0144799]

Allele Dmel\pUf689

Allele Dmel\pUf68⁹