eye, with Scer\GAL4GMR.PF
macrochaeta & mesothoracic tergum, with Scer\GAL4sca-537.4
macrochaeta & scutellum, with Scer\GAL4sca-537.4
wing, with Scer\GAL4vg.PM
The expression of egrGS9830 under the control of Scer\GAL4ptc-559.1 induces invasive cell migration in the ptc domain along the anterior-posterior compartment boundary of the third instar larval wing disc.
Expressing egrGS9830 under the control of Scer\GAL4ptc.PU induces some cells at the wing disc A/P boundary to delaminate and migrate to the posterior compartment.
The expression of egrGS9830 under the control of Scer\GAL4GMR.PU leads to a severe increase in apoptosis at the morphogenetic furrow of the third instar larval eye disc and to small and rough eye phenotypes in adults, as compared to controls; expression under the control of Scer\GAL4ptc-559.1 leads to a severe increase in apoptosis around the anterior-posterior compartment boundary of the third instar larval wing disc and to a highly penetrant anterior crossvein loss in the adult wing, as compared to controls.
Expression of egrGS9830 under the control of Scer\GAL4ptc.PU in cells of the wing disc proper has no significant effect on the morphology or proliferation of the overlying peripodial membrane cells in third instar larvae.
Expression of egrGS9830 under the control of Scer\GAL4GMR.PF results in cell death of the developing eye tissue, such that the adult eye is severely reduced in size.
egrGS9830 mutant flies show a slight increased susceptibility to challenge by Enterococcus faecalis compared to wild type flies.
Expression of egrGS9830 under the control of Scer\GAL4GMR.PF results in ablation of the adult eye. Co-expression of egrIR.Scer\UAS under the control of Scer\GAL4GMR.PF suppresses this phenotype.
When egrGS9830 is driven by Scer\GAL4GMR.PF, a strong reduced eye phenotype is seen. The eye discs in these animals show massive apoptotic cell death. When egrGS9830 is driven by Scer\GAL4vg.PM wing formation is completely blocked. When egrGS9830 is driven by Scer\GAL4sca-537.4, disorganised macrochaetae are seen in the notum and scutellum. Also severe developmental defects are seen in the abdomen.
Flies expressing egrGS9830 under the control of Scer\GAL4GMR.PF have a small-eye phenotype.
Scer\GAL4GMR.PU, egrGS9830 has visible | adult stage phenotype, non-enhanceable by spoonKH.UAS.Tag:HA/Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has decreased size | adult stage phenotype, non-enhanceable by spoonKH.UAS.Tag:HA/Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has visible | adult stage phenotype, non-enhanceable by spoonTudor.UAS.Tag:HA/Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has decreased size | adult stage phenotype, non-enhanceable by spoonTudor.UAS.Tag:HA/Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has visible | adult stage phenotype, suppressible | partially by spoonKG02745
Scer\GAL4GMR.PU, egrGS9830 has decreased size | adult stage phenotype, suppressible | partially by spoonKG02745
Scer\GAL4ptc-559.1, egrGS9830 has abnormal cell migration | third instar larval stage phenotype, suppressible | partially by Scer\GAL4ptc-559.1/Toll-7GD14417
Scer\GAL4ptc-559.1, egrGS9830 has abnormal cell migration | third instar larval stage phenotype, suppressible | partially by Scer\GAL4ptc-559.1/Toll-7HM05230
Scer\GAL4ptc.PU, egrGS9830 has abnormal cell migration | third instar larval stage phenotype, suppressible | partially by hep[+]/hep1
Scer\GAL4ptc.PU, egrGS9830 has abnormal cell migration | third instar larval stage phenotype, suppressible | partially by licG0252/lic[+]
Scer\GAL4ptc.PU, egrGS9830 has abnormal cell migration | third instar larval stage phenotype, suppressible by licG0252/hep[+]/lic[+]/hep1
Scer\GAL4GMR.PU, egrGS9830 has abnormal size | adult stage phenotype, suppressible | partially by Glyatc02982/Glyat[+]
Scer\GAL4GMR.PU, egrGS9830 has visible | adult stage phenotype, suppressible | partially by Glyatc02982/Glyat[+]
Scer\GAL4GMR.PU, egrGS9830 has abnormal size | adult stage phenotype, suppressible | partially by GlyatTH00482, Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has visible | adult stage phenotype, suppressible | partially by GlyatTH00482, Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has abnormal size | adult stage phenotype, suppressible | partially by bskNIG.5680R/Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has visible | adult stage phenotype, suppressible | partially by bskNIG.5680R/Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has increased cell death | third instar larval stage phenotype, suppressible | partially by Glyatc02982/Glyat[+]
Scer\GAL4GMR.PU, egrGS9830 has increased cell death | third instar larval stage phenotype, suppressible | partially by GlyatTH00482, Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has increased cell death | third instar larval stage phenotype, suppressible | partially by bskNIG.5680R/Scer\GAL4GMR.PU
Scer\GAL4ptc-559.1, egrGS9830 has increased cell death | third instar larval stage phenotype, suppressible | partially by Glyatc02982/Glyat[+]
Scer\GAL4ptc-559.1, egrGS9830 has increased cell death | third instar larval stage phenotype, suppressible | partially by GlyatTH00482, Scer\GAL4ptc-559.1
Scer\GAL4ptc-559.1, egrGS9830 has increased cell death | third instar larval stage phenotype, suppressible | partially by Scer\GAL4ptc-559.1/bskNIG.5680R
Scer\GAL4GMR.PF, egrGS9830 has visible phenotype, suppressible by Tak1K46R.M.UAS/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has visible phenotype, suppressible by Scer\GAL4GMR.PF/Tak1Ct.UASp.Tag:HA
Scer\GAL4GMR.PF, egrGS9830 has visible phenotype, suppressible by slpr::Tak1SAAATCt.UASp.Tag:HA/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has visible phenotype, suppressible by slpr::Tak1TSK.UASp.Tag:HA/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has visible phenotype, suppressible by Scer\GAL4GMR.PF/slpr::Tak1STCt.UASp.Tag:HA
Scer\GAL4GMR.PF, egrGS9830 has visible phenotype, suppressible by slpr::Tak1TSAAA.UASp.Tag:HA/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has visible phenotype, suppressible | partially by hep[+]/hep1
Scer\GAL4GMR.PF, egrGS9830 has visible phenotype, suppressible by Df(1)E128/+
Scer\GAL4GMR.PF, egrGS9830 has visible phenotype, suppressible by wgnRNAi.UAS/Scer\GAL4GMR.PF
Scer\GAL4GMR.PU, egrGS9830 has visible | adult stage phenotype, non-suppressible by spoonKH.UAS.Tag:HA/Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has decreased size | adult stage phenotype, non-suppressible by spoonKH.UAS.Tag:HA/Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has visible | adult stage phenotype, non-suppressible by spoonTudor.UAS.Tag:HA/Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has decreased size | adult stage phenotype, non-suppressible by spoonTudor.UAS.Tag:HA/Scer\GAL4GMR.PU
Scer\GAL4GMR.PF, egrGS9830 has visible phenotype, non-suppressible by slpr::Tak1STK.UASp.Tag:HA/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has visible phenotype, non-suppressible by slprAAA.UASp.Tag:HA/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has visible phenotype, non-suppressible by slpr921/slpr[+]
Scer\GAL4GMR.PF, egrGS9830 has visible phenotype, non-suppressible by slprD314Y.KM.UASp/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, enhanceable by Diap14/th[+]
Scer\GAL4GMR.PU, egrGS9830 has eye phenotype, non-enhanceable by spoonKH.UAS.Tag:HA/Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has eye phenotype, non-enhanceable by spoonTudor.UAS.Tag:HA/Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has eye phenotype, suppressible | partially by spoonKG02745
Scer\GAL4GMR.PU, egrGS9830 has ommatidium phenotype, suppressible | partially by spoonKG02745
Scer\GAL4ptc-559.1, egrGS9830 has anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype, suppressible | partially by Scer\GAL4ptc-559.1/Toll-7GD14417
Scer\GAL4ptc-559.1, egrGS9830 has anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype, suppressible | partially by Scer\GAL4ptc-559.1/Toll-7HM05230
Scer\GAL4ptc.PU, egrGS9830 has anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype, suppressible | partially by hep[+]/hep1
Scer\GAL4ptc.PU, egrGS9830 has anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype, suppressible | partially by licG0252/lic[+]
Scer\GAL4ptc.PU, egrGS9830 has anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype, suppressible by licG0252/hep[+]/lic[+]/hep1
Scer\GAL4GMR.PU, egrGS9830 has eye phenotype, suppressible | partially by Glyatc02982/Glyat[+]
Scer\GAL4GMR.PU, egrGS9830 has eye phenotype, suppressible | partially by GlyatTH00482, Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has eye phenotype, suppressible | partially by bskNIG.5680R/Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has eye disc morphogenetic furrow | third instar larval stage phenotype, suppressible | partially by Glyatc02982/Glyat[+]
Scer\GAL4GMR.PU, egrGS9830 has eye disc morphogenetic furrow | third instar larval stage phenotype, suppressible | partially by GlyatTH00482, Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has eye disc morphogenetic furrow | third instar larval stage phenotype, suppressible | partially by bskNIG.5680R/Scer\GAL4GMR.PU
Scer\GAL4ptc-559.1, egrGS9830 has anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype, suppressible | partially by Glyatc02982/Glyat[+]
Scer\GAL4ptc-559.1, egrGS9830 has anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype, suppressible | partially by GlyatTH00482, Scer\GAL4ptc-559.1
Scer\GAL4ptc-559.1, egrGS9830 has anterior-posterior compartment boundary of the wing disc | third instar larval stage phenotype, suppressible | partially by Scer\GAL4ptc-559.1/bskNIG.5680R
Scer\GAL4ptc-559.1, egrGS9830 has anterior crossvein | third instar larval stage phenotype, suppressible | partially by Glyatc02982/Glyat[+]
Scer\GAL4ptc-559.1, egrGS9830 has anterior crossvein | third instar larval stage phenotype, suppressible | partially by GlyatTH00482, Scer\GAL4ptc-559.1
Scer\GAL4ptc-559.1, egrGS9830 has anterior crossvein | third instar larval stage phenotype, suppressible | partially by Scer\GAL4ptc-559.1/bskNIG.5680R
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible by Tak1K46R.M.UAS/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible by Scer\GAL4GMR.PF/Tak1Ct.UASp.Tag:HA
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible by slpr::Tak1SAAATCt.UASp.Tag:HA/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible by slpr::Tak1TSK.UASp.Tag:HA/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible by Scer\GAL4GMR.PF/slpr::Tak1STCt.UASp.Tag:HA
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible by slpr::Tak1TSAAA.UASp.Tag:HA/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible | partially by hep[+]/hep1
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible by hep1
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible | partially by bsk2
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible | partially by msn172
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible | partially by BacA\p35UAS.cHa, Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible by Scer\GAL4GMR.PF/Tak1K46R.UAS
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible by bskDN.UAS/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible by Diap1UAS.Tag:HA, Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible | partially by DroncC318G.UAS, Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible by Df(1)E128/+
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, suppressible by wgnRNAi.UAS/Scer\GAL4GMR.PF
Scer\GAL4GMR.PU, egrGS9830 has eye phenotype, non-suppressible by spoonTudor.UAS.Tag:HA/Scer\GAL4GMR.PU
Scer\GAL4GMR.PU, egrGS9830 has eye phenotype, non-suppressible by spoonKH.UAS.Tag:HA/Scer\GAL4GMR.PU
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, non-suppressible by slpr::Tak1STK.UASp.Tag:HA/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, non-suppressible by slprAAA.UASp.Tag:HA/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, non-suppressible by slpr921/slpr[+]
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, non-suppressible by slprD314Y.KM.UASp/Scer\GAL4GMR.PF
Scer\GAL4GMR.PF, egrGS9830 has eye phenotype, non-suppressible by JraIA109
The increased apoptosis at the morphogenetic furrow of the third instar larval eye disc and the decreased eye size in adults resulting from the expression of egrGS9830 under the control of Scer\GAL4GMR.PU are partially suppressed by the co-expression of either GlyatTH00482 or bskNIG.5680R, or by heterozygosity for Glyatc02982; the increased apoptosis around the anterior-posterior compartment boundary of the third instar larval wing disc and the highly penetrant anterior crossvein loss in the adult wing resulting from the expression of egrGS9830 under the control of Scer\GAL4ptc-559.1 are strongly suppressed by the co-expression of either GlyatTH00482 or bskNIG.5680R, or by heterozygosity for Glyatc02982.
Expression of Tak1K46R.M.Scer\UAS suppresses the reduction in eye size seen when egrGS9830 is expressed under the control of Scer\GAL4GMR.PF.
Expression of Tak1Ct.Scer\UAS.P\T.T:Ivir\HA1 suppresses the reduction in eye size seen when egrGS9830 is expressed under the control of Scer\GAL4GMR.PF.
Expression of slpr::Tak1SAAATCt.Scer\UAS.P\T.T:Ivir\HA1 suppresses the reduction in eye size seen when egrGS9830 is expressed under the control of Scer\GAL4GMR.PF.
Expression of slpr::Tak1TSK.Scer\UAS.P\T.T:Ivir\HA1 suppresses the reduction in eye size seen when egrGS9830 is expressed under the control of Scer\GAL4GMR.PF.
Expression of slpr::Tak1STCt.Scer\UAS.P\T.T:Ivir\HA1 suppresses the reduction in eye size seen when egrGS9830 is expressed under the control of Scer\GAL4GMR.PF.
Expression of slpr::Tak1TSAAA.Scer\UAS.P\T.T:Ivir\HA1 suppresses the reduction in eye size seen when egrGS9830 is expressed under the control of Scer\GAL4GMR.PF.
Expression of slpr::Tak1STK.Scer\UAS.P\T.T:Ivir\HA1 does not suppress the reduction in eye size seen when egrGS9830 is expressed under the control of Scer\GAL4GMR.PF.
The eye ablation phenotype seen in adults expressing egrGS9830 under the control of Scer\GAL4GMR.PF is not suppressed by either slpr921/+ or by coexpression of slprD314Y.KM.Scer\UAS.P\T under the control of Scer\GAL4GMR.PF.
The eye ablation phenotype seen in adults expressing egrGS9830 under the control of Scer\GAL4GMR.PF is partially suppressed by hep1/+.
The eye ablation phenotype seen in adults expressing egrGS9830 under the control of Scer\GAL4GMR.PF is almost completely suppressed by coexpression of Tak1K46R.M.Scer\UAS under the control of Scer\GAL4GMR.PF.
The addition of th4/+ to egrGS9830, Scer\GAL4GMR.PF animals leads to a completely ablated eye phenotype, an enhancement of the egrGS9830, Scer\GAL4GMR.PF phenotype. The addition of bskDN.Scer\UAS to egrGS9830, Scer\GAL4GMR.PF animals leads to a strong suppression of the eye phenotype. The addition of bsk2/+ to egrGS9830, Scer\GAL4GMR.PF animals leads to a suppression of the eye phenotype. The addition of hep1/+ to egrGS9830, Scer\GAL4GMR.PF animals leads to a suppression of the eye phenotype. The addition of hep1/Y leads to an almost complete suppression of the eye phenotype The addition of Tak1K46R.Scer\UAS to egrGS9830, Scer\GAL4GMR.PF animals leads to a suppression of the eye phenotype. The addition of JraIA109 to egrGS9830, Scer\GAL4GMR.PF animals fails to suppress the eye phenotype.
Df(1)E128/+ suppresses the small eye phenotype caused by expression of egrGS9830 under the control of Scer\GAL4GMR.PF. Co-expression of wgndsRNA.Scer\UAS suppresses the small eye phenotype caused by expression of egrGS9830 under the control of Scer\GAL4GMR.PF.
egrGS9830 is rescued by egrRNAi.UAS/Scer\GAL4GMR.PF
Expression of slprAAA.Scer\UAS.P\T.T:Ivir\HA1 does not suppress the reduction in eye size seen when egrGS9830 is expressed under the control of Scer\GAL4GMR.PF.
Separable from: NimC1del.