FlyBase Allele Report: Scer\GAL4[Ugt36A1.PK]

Drives expression n the posterior signalling centre of the lymph gland primary lobe, in pericardial cells (nephrocytes), and in abdominal Pdf neurons.

(FlyBase Curators, 2017)

Scer\GAL4^Ugt36A1.PK drives expression in nephrocytes, and in the gut.

(Pendse et al., 2013)

Scer\GAL4^Ugt36A1.PK drives expression at a high level in the posterior signalling center of the primary lobe of the lymph gland.

(Sinenko et al., 2011)

Scer\GAL4^Ugt36A1.PK drives expression the embryonic lymph gland after dorsal closure. Scer\GAL4^Ugt36A1.PK does not drive expression in embryonic macrophages, and does not coincide with that of Scer\GAL4^crq.PO, indicating that these drivers mark distinct hemocyte lineages.

(Honti et al., 2010)

Marker for

Pdf neuron of abdominal neuromere

(Shafer and Taghert, 2009)

Reflects expression of

Ugt36A1

(Hartley et al., 2016, Lim et al., 2014, Sinenko et al., 2011, Honti et al., 2010, Shafer and Taghert, 2009)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Phenotypic Data

Phenotypic Class

chemical sensitive, with Amnionless^UAS.cZa

(Zhang et al., 2013)

chemical sensitive, with Cubn^GD6458

(Zhang et al., 2013)

chemical sensitive, with HHEX^GD4293

(Pendse et al., 2013)

endocytosis defective | adult stage, with Hsap\APOL1^G0.UAS.cFa

(Fu et al., 2017)

endocytosis defective | adult stage, with Hsap\APOL1^G0.UAS.cKa

(Kruzel-Davila et al., 2017)

endocytosis defective | adult stage, with Hsap\APOL1^G1.UAS.cFa

(Fu et al., 2017)

endocytosis defective | adult stage, with Hsap\APOL1^G1.UAS.cKa

(Kruzel-Davila et al., 2017)

endocytosis defective | adult stage, with Hsap\APOL1^G2.UAS.cKa

(Kruzel-Davila et al., 2017)

increased cell size | adult stage | progressive, with Hsap\APOL1^G0.UAS.cFa

(Fu et al., 2017)

increased cell size | adult stage | progressive, with Hsap\APOL1^G1.UAS.cFa

(Fu et al., 2017)

lethal, with Hsap\KMT2A::Hsap\MLLT3^{UAS.C.Tag:FLAG}

(Muyrers-Chen et al., 2004)

lethal, with Mec2^HMJ23038

(Fu et al., 2017)

lethal | chemical conditional, with HHEX^GD4293

(Pendse et al., 2013)

lethal - all die before end of embryonic stage | heat sensitive

(Kimbrell et al., 2002)

lethal - all die before end of pupal stage, with fh^{dsRNA.UAS.cLa}

(Llorens et al., 2007)

lethal - all die before end of pupal stage, with fh^UAS.cLa

(Llorens et al., 2007)

melanotic mass phenotype, with hop^Tum.UAS

(Kimbrell et al., 2002)

melanotic mass phenotype, with hop^UAS.cHa

(Kimbrell et al., 2002)

oxidative stress response defective, with Cat^GD1291

(Lim et al., 2014)

oxidative stress response defective, with Cat^UAS.cAa

(Lim et al., 2014)

oxidative stress response defective, with Cat^UAS.cAa, Scer\GAL80^ts.αTub84B

(Lim et al., 2014)

oxidative stress response defective, with lic^GD7546

(Lim et al., 2014)

oxidative stress response defective, with p38b^DN.UAS

(Lim et al., 2014)

oxidative stress response defective, with Scer\GAL80^ts.αTub84B, p38b^DN.UAS

(Lim et al., 2014)

oxidative stress response defective, with Sod1^UAS.cWa

(Lim et al., 2014)

oxidative stress response defective, with Sod2^UAS.cMa

(Lim et al., 2014)

short lived, with Alg1^HMC03502

(Fu et al., 2017)

short lived, with Amnionless^HMS02353

(Fu et al., 2017)

short lived, with cindr^GLV21035

(Fu et al., 2017)

short lived, with cindr^HMS01795

(Fu et al., 2017)

short lived, with cindr^HMS01892

(Fu et al., 2017)

short lived, with cindr^TRiP.cUa

(Fu et al., 2017)

short lived, with Col4a1^HMC02910

(Fu et al., 2017)

short lived, with Coq2^HMC03492

(Fu et al., 2017)

short lived, with Coq2^JF02380

(Fu et al., 2017)

short lived, with Coq6^GD4930

(Fu et al., 2017)

short lived, with Cubn^HMS03167

(Fu et al., 2017)

short lived, with Cubn^JF03118

(Fu et al., 2017)

short lived, with dally^HMS00905

(Fu et al., 2017)

short lived, with dally^JF03175

(Fu et al., 2017)

short lived, with Hsap\APOL1^G0.UAS.cFa

(Fu et al., 2017)

short lived, with Hsap\APOL1^G1.UAS.cFa

(Fu et al., 2017)

short lived, with Kank^HMS00319

(Fu et al., 2017)

short lived, with Lam^GL00577

(Fu et al., 2017)

short lived, with Lam^HMC04816

(Fu et al., 2017)

short lived, with Lam^JF01389

(Fu et al., 2017)

short lived, with LanB1^HMS02451

(Fu et al., 2017)

short lived, with Lmx1a^HMC03113

(Fu et al., 2017)

short lived, with Lmx1a^JF02194

(Fu et al., 2017)

short lived, with mew^HMS02849

(Fu et al., 2017)

short lived, with mew^JF02694

(Fu et al., 2017)

short lived, with Myo61F^HMS02253

(Fu et al., 2017)

short lived, with mys^HMS00043

(Fu et al., 2017)

short lived, with mys^JF02819

(Fu et al., 2017)

short lived, with Pdss2^HMC03486

(Fu et al., 2017)

short lived, with Pdss2^HMS02674

(Fu et al., 2017)

short lived, with Pmm2^HMC03480

(Fu et al., 2017)

short lived, with Pmm2^HMS02649

(Fu et al., 2017)

short lived, with RhoGAP92B^HMS00268

(Fu et al., 2017)

short lived, with RhoGDI^HMS02150

(Fu et al., 2017)

short lived, with sbr^HM05135

(Fu et al., 2017)

short lived, with sbr^HMS00273

(Fu et al., 2017)

short lived, with sbr^HMS02414

(Fu et al., 2017)

short lived, with sns^KK108577

(Fu et al., 2017)

short lived, with sv^JF02582

(Fu et al., 2017)

short lived, with Trpγ^HMC03542

(Fu et al., 2017)

short lived, with Trpγ^JF01243

(Fu et al., 2017)

short lived, with Trpγ^JF01244

(Fu et al., 2017)

short lived, with zip^GL00623

(Fu et al., 2017)

short lived, with zip^HMS01618

(Fu et al., 2017)

short lived, with zip^HMS01703

(Fu et al., 2017)

some die during embryonic stage | heat sensitive

(Kimbrell et al., 2002)

some die during pupal stage, with fh^{dsRNA.UAS.cLa}

(Llorens et al., 2007)

some die during pupal stage, with fh^UAS.cLa

(Llorens et al., 2007)

viable, with Amnionless^UAS.cZa

(Zhang et al., 2013)

viable, with Cubn^GD6458

(Zhang et al., 2013)

viable, with Hsap\KMT2A::Hsap\AFF1^UAS.cMa

(Muyrers-Chen et al., 2004)

viable, with Hsap\KMT2A^{UAS.C.Tag:FLAG}

(Muyrers-Chen et al., 2004)

visible

(Kimbrell et al., 2002)

Phenotype Manifest In

adult heart, with Amnionless^KK103998

(Hartley et al., 2016)

adult heart, with Cat^GD1291

(Lim et al., 2014)

adult heart, with Cat^UAS.cAa

(Lim et al., 2014)

adult heart, with Cat^UAS.cAa, Scer\GAL80^ts.αTub84B

(Lim et al., 2014)

adult heart, with Klf15^JF02420

(Hartley et al., 2016)

adult heart, with lic^GD7546

(Lim et al., 2014)

adult heart, with p38b^DN.UAS

(Lim et al., 2014)

adult heart, with Scer\GAL80^ts.αTub84B, p38b^DN.UAS

(Lim et al., 2014)

adult heart, with Sod1^UAS.cWa

(Lim et al., 2014)

adult heart, with Sod2^UAS.cMa

(Lim et al., 2014)

adult pericardial cell, with Actn^HMS00193

(Fu et al., 2017)

adult pericardial cell, with Alg1^HMC03502

(Fu et al., 2017)

adult pericardial cell, with Amnionless^HMS02353

(Fu et al., 2017)

adult pericardial cell, with cindr^GLV21035

(Fu et al., 2017)

adult pericardial cell, with cindr^HMS01795

(Fu et al., 2017)

adult pericardial cell, with cindr^HMS01892

(Fu et al., 2017)

adult pericardial cell, with cindr^TRiP.cUa

(Fu et al., 2017)

adult pericardial cell, with Col4a1^HMC02910

(Fu et al., 2017)

adult pericardial cell, with Coq2^HMC03492

(Fu et al., 2017)

adult pericardial cell, with Coq2^JF02380

(Fu et al., 2017)

adult pericardial cell, with Coq6^GD4930

(Fu et al., 2017)

adult pericardial cell, with Coq8^GL00260

(Fu et al., 2017)

adult pericardial cell, with Coq8^GL01574

(Fu et al., 2017)

adult pericardial cell, with Coq8^HMS04484

(Fu et al., 2017)

adult pericardial cell, with Cubn^HMS03167

(Fu et al., 2017)

adult pericardial cell, with Cubn^JF03118

(Fu et al., 2017)

adult pericardial cell, with E2f1^HMS01541

(Fu et al., 2017)

adult pericardial cell, with E2f1^JF01741

(Fu et al., 2017)

adult pericardial cell, with E2f1^JF02718

(Fu et al., 2017)

adult pericardial cell, with emp^GLC01817

(Fu et al., 2017)

adult pericardial cell, with emp^HMS02195

(Fu et al., 2017)

adult pericardial cell, with form3^HMS00393

(Fu et al., 2017)

adult pericardial cell, with Hsap\APOL1^G0.UAS.cKa

(Kruzel-Davila et al., 2017)

adult pericardial cell, with Hsap\APOL1^G1.UAS.cKa

(Kruzel-Davila et al., 2017)

adult pericardial cell, with Hsap\APOL1^G2.UAS.cKa

(Kruzel-Davila et al., 2017)

adult pericardial cell, with Kank^HMS00319

(Fu et al., 2017)

adult pericardial cell, with Klf15^JF02420

(Ivy et al., 2015)

adult pericardial cell, with Klf15^KK108739

(Ivy et al., 2015)

adult pericardial cell, with Lam^GL00577

(Fu et al., 2017)

adult pericardial cell, with Lam^HMC04816

(Fu et al., 2017)

adult pericardial cell, with Lam^JF01389

(Fu et al., 2017)

adult pericardial cell, with LanB1^HMS02451

(Fu et al., 2017)

adult pericardial cell, with Lmx1a^HMC03113

(Fu et al., 2017)

adult pericardial cell, with Lmx1a^JF02194

(Fu et al., 2017)

adult pericardial cell, with Marcal1^HMS00587

(Fu et al., 2017)

adult pericardial cell, with mew^HMS02849

(Fu et al., 2017)

adult pericardial cell, with mew^JF02694

(Fu et al., 2017)

adult pericardial cell, with Myo61F^HMS02253

(Fu et al., 2017)

adult pericardial cell, with mys^HMS00043

(Fu et al., 2017)

adult pericardial cell, with mys^JF02819

(Fu et al., 2017)

adult pericardial cell, with Pmm2^HMC03480

(Fu et al., 2017)

adult pericardial cell, with Pmm2^HMS02649

(Fu et al., 2017)

adult pericardial cell, with RhoGAP92B^HMS00268

(Fu et al., 2017)

adult pericardial cell, with RhoGDI^HMS02150

(Fu et al., 2017)

adult pericardial cell, with sbr^HM05135

(Fu et al., 2017)

adult pericardial cell, with sbr^HMS00273

(Fu et al., 2017)

adult pericardial cell, with sbr^HMS02414

(Fu et al., 2017)

adult pericardial cell, with sns^KK108577

(Fu et al., 2017)

adult pericardial cell, with sv^JF02582

(Fu et al., 2017)

adult pericardial cell, with Trpγ^HMC03542

(Fu et al., 2017)

adult pericardial cell, with Trpγ^JF01243

(Fu et al., 2017)

adult pericardial cell, with Trpγ^JF01244

(Fu et al., 2017)

adult pericardial cell, with Tsp74F^HMS01966

(Fu et al., 2017)

adult pericardial cell, with zip^GL00623

(Fu et al., 2017)

adult pericardial cell, with zip^HMS01618

(Fu et al., 2017)

adult pericardial cell, with zip^HMS01703

(Fu et al., 2017)

adult pericardial cell | progressive, with Hsap\APOL1^G0.UAS.cFa

(Fu et al., 2017)

adult pericardial cell | progressive, with Hsap\APOL1^G1.UAS.cFa

(Fu et al., 2017)

adult pericardial cell | supernumerary, with Klf15^UAS.cIa

(Ivy et al., 2015)

embryonic/larval pericardial cell, with Amnionless^KK103998

(Zhang et al., 2013)

embryonic/larval pericardial cell, with Amnionless^VDRC.cUa

(Zhang et al., 2013)

embryonic/larval pericardial cell, with Cdc42^JF02855

(Zhang et al., 2013)

embryonic/larval pericardial cell, with Cubn^GD6458

(Zhang et al., 2013, Zhang et al., 2013)

embryonic/larval pericardial cell, with fh^UAS.cLa

(Llorens et al., 2007)

embryonic/larval pericardial cell, with kirre^GD14476

(Zhang et al., 2013)

embryonic/larval pericardial cell, with kirre^KK107679

(Zhang et al., 2013)

embryonic/larval pericardial cell, with Mec2^KK110818

(Zhang et al., 2013)

embryonic/larval pericardial cell, with Rac1^JF02813

(Zhang et al., 2013)

embryonic/larval pericardial cell, with sns^GD65

(Zhang et al., 2013)

embryonic/larval pericardial cell, with sns^KK108577

(Zhang et al., 2013)

eye

(Kimbrell et al., 2002)

lamellocyte | larval stage, with ND-75^GD6309

(Sinenko et al., 2011)

lamellocyte | larval stage, with spi^s.UAS

(Sinenko et al., 2011)

melanotic mass, with hop^Tum.UAS

(Kimbrell et al., 2002)

melanotic mass, with hop^UAS.cHa

(Kimbrell et al., 2002)

nephrocyte diaphragm, with Mec2^KK110818

(Zhang et al., 2013)

nephrocyte diaphragm, with sns^GD65

(Zhang et al., 2013)

nephrocyte diaphragm, with sns^KK108577

(Zhang et al., 2013)

nephrocyte diaphragm | adult stage, with cindr^TRiP.cUa

(Fu et al., 2017)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^Ugt36A1.PK, Sod1^UAS.cWa has oxidative stress response defective phenotype, enhanceable by Sod2^UAS.cMa/Scer\GAL4^Hand.PA

(Lim et al., 2014)

Scer\GAL4^Ugt36A1.PK, Sod2^UAS.cMa has oxidative stress response defective phenotype, enhanceable by Scer\GAL4^Hand.PA/Sod1^UAS.cWa

(Lim et al., 2014)

Suppressed by

Statement

Reference

Scer\GAL4^Ugt36A1.PK, cindr^TRiP.cUa has short lived phenotype, suppressible | partially by Hsap\CD2AP^UAS.cFa, Scer\GAL4^Ugt36A1.PK

(Fu et al., 2017)

Cat^UAS.cAa, Scer\GAL4^Ugt36A1.PK, Scer\GAL80^ts.αTub84B has oxidative stress response defective phenotype, suppressible by p38a¹³/p38b^156A

(Lim et al., 2014)

Cat^GD1291, Scer\GAL4^Ugt36A1.PK has oxidative stress response defective phenotype, suppressible by p38b^UAS.ORF, Scer\GAL4^Ugt36A1.PK

(Lim et al., 2014)

NOT suppressed by

Statement

Reference

Scer\GAL4^Ugt36A1.PK, cindr^TRiP.cUa has short lived phenotype, non-suppressible by Hsap\CD2AP^K301M.UAS, Scer\GAL4^Ugt36A1.PK

(Fu et al., 2017)

Suppressor of

Statement

Reference

Hsap\CD2AP^UAS.cFa, Scer\GAL4^Ugt36A1.PK is a suppressor | partially of short lived phenotype of Scer\GAL4^Ugt36A1.PK, cindr^TRiP.cUa

(Fu et al., 2017)

p38b^UAS.ORF, Scer\GAL4^Ugt36A1.PK is a suppressor of oxidative stress response defective phenotype of Cat^GD1291, Scer\GAL4^Ugt36A1.PK

(Lim et al., 2014)

NOT Suppressor of

Statement

Reference

Hsap\CD2AP^K301M.UAS, Scer\GAL4^Ugt36A1.PK is a non-suppressor of short lived phenotype of Scer\GAL4^Ugt36A1.PK, cindr^TRiP.cUa

(Fu et al., 2017)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^Ugt36A1.PK, Sod1^UAS.cWa has adult heart phenotype, non-enhanceable by Sod2^UAS.cMa/Scer\GAL4^Hand.PA

(Lim et al., 2014)

Scer\GAL4^Ugt36A1.PK, Sod2^UAS.cMa has adult heart phenotype, non-enhanceable by Scer\GAL4^Hand.PA/Sod1^UAS.cWa

(Lim et al., 2014)

Suppressed by

Statement

Reference

Scer\GAL4^Ugt36A1.PK, cindr^TRiP.cUa has adult pericardial cell phenotype, suppressible | partially by Hsap\CD2AP^UAS.cFa, Scer\GAL4^Ugt36A1.PK

(Fu et al., 2017)

Scer\GAL4^Ugt36A1.PK, cindr^TRiP.cUa has nephrocyte diaphragm | adult stage phenotype, suppressible | partially by Hsap\CD2AP^UAS.cFa, Scer\GAL4^Ugt36A1.PK

(Fu et al., 2017)

Cat^UAS.cAa, Scer\GAL4^Ugt36A1.PK, Scer\GAL80^ts.αTub84B has adult heart phenotype, suppressible by p38a¹³/p38b^156A

(Lim et al., 2014)

Cat^GD1291, Scer\GAL4^Ugt36A1.PK has adult heart phenotype, suppressible by p38b^UAS.ORF, Scer\GAL4^Ugt36A1.PK

(Lim et al., 2014)

ND-75^GD6309, Scer\GAL4^Ugt36A1.PK has lamellocyte | larval stage phenotype, suppressible by foxo^UAS.cPa, Scer\GAL4^Ugt36A1.PK

(Sinenko et al., 2011)

ND-75^GD6309, Scer\GAL4^Ugt36A1.PK has lamellocyte | larval stage phenotype, suppressible by Scer\GAL4^Antp-10/spi^NIG.10334R

(Sinenko et al., 2011)

ND-75^GD6309, Scer\GAL4^Ugt36A1.PK has lamellocyte | larval stage phenotype, suppressible by Akt1^GD1361, Scer\GAL4^Ugt36A1.PK

(Sinenko et al., 2011)

ND-75^GD6309, Scer\GAL4^Ugt36A1.PK has lamellocyte | larval stage phenotype, suppressible by Akt1^KK100495, Scer\GAL4^Ugt36A1.PK

(Sinenko et al., 2011)

NOT suppressed by

Statement

Reference

Scer\GAL4^Ugt36A1.PK, cindr^TRiP.cUa has adult pericardial cell phenotype, non-suppressible by Hsap\CD2AP^K301M.UAS, Scer\GAL4^Ugt36A1.PK

(Fu et al., 2017)

Scer\GAL4^Ugt36A1.PK, cindr^TRiP.cUa has nephrocyte diaphragm | adult stage phenotype, non-suppressible by Hsap\CD2AP^K301M.UAS, Scer\GAL4^Ugt36A1.PK

(Fu et al., 2017)

Suppressor of

Statement

Reference

Hsap\CD2AP^UAS.cFa, Scer\GAL4^Ugt36A1.PK is a suppressor | partially of adult pericardial cell phenotype of Scer\GAL4^Ugt36A1.PK, cindr^TRiP.cUa

(Fu et al., 2017)

Hsap\CD2AP^UAS.cFa, Scer\GAL4^Ugt36A1.PK is a suppressor | partially of nephrocyte diaphragm | adult stage phenotype of Scer\GAL4^Ugt36A1.PK, cindr^TRiP.cUa

(Fu et al., 2017)

p38b^UAS.ORF, Scer\GAL4^Ugt36A1.PK is a suppressor of adult heart phenotype of Cat^GD1291, Scer\GAL4^Ugt36A1.PK

(Lim et al., 2014)

foxo^UAS.cPa, Scer\GAL4^Ugt36A1.PK is a suppressor of lamellocyte | larval stage phenotype of ND-75^GD6309, Scer\GAL4^Ugt36A1.PK

(Sinenko et al., 2011)

Akt1^GD1361, Scer\GAL4^Ugt36A1.PK is a suppressor of lamellocyte | larval stage phenotype of ND-75^GD6309, Scer\GAL4^Ugt36A1.PK

(Sinenko et al., 2011)

Akt1^KK100495, Scer\GAL4^Ugt36A1.PK is a suppressor of lamellocyte | larval stage phenotype of ND-75^GD6309, Scer\GAL4^Ugt36A1.PK

(Sinenko et al., 2011)

NOT Suppressor of

Statement

Reference

Hsap\CD2AP^K301M.UAS, Scer\GAL4^Ugt36A1.PK is a non-suppressor of adult pericardial cell phenotype of Scer\GAL4^Ugt36A1.PK, cindr^TRiP.cUa

(Fu et al., 2017)

Hsap\CD2AP^K301M.UAS, Scer\GAL4^Ugt36A1.PK is a non-suppressor of nephrocyte diaphragm | adult stage phenotype of Scer\GAL4^Ugt36A1.PK, cindr^TRiP.cUa

(Fu et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Amnionless^UAS.cZa/Scer\GAL4^Ugt36A1.PK rescues Amnionless^VDRC.cUa

(Zhang et al., 2013)

Partially rescues

Scer\GAL4^Ugt36A1.PK/Adgf-A^UAS.Tag:MYC partially rescues Adgf-A^Karel.3'/Adgf-A^Karel.5'

(Dolezal et al., 2005)

Scer\GAL4^Ugt36A1.PK/Adgf-A^UAS.Tag:MYC partially rescues Dp(3;3)Karel

(Dolezal et al., 2005)

Fails to rescue

Gγ1^{UAS.Y.Tag:FLAG}/Scer\GAL4^Ugt36A1.PK fails to rescue Gγ1^k08017

(Yi et al., 2006)

Scer\GAL4^Ugt36A1.PK/Hmgcr^UAS.cvDa fails to rescue Hmgcr⁰¹¹⁵²

(Yi et al., 2006)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

6903

P{Ugt36A1-GAL4.K}43A, y¹ w^*

67608

w^*; P{Ugt36A1-GAL4.K}11C, P{UAS-GFP.U}2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Scer\GAL4^Dot.PK

Scer\GAL4^Ugt36A1.PK

Name Synonyms

Dorothy promoter construct of Kimbrell

(Kimbrell et al., 2002)

Secondary FlyBase IDs

References (34)

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