Allele Dmel\Gp150^P8

General Information
Symbol	Dmel\Gp150^P8	Species	D. melanogaster
Name		FlyBase ID	FBal0138495
Feature type	allele	Associated gene	Dmel\Gp150

Map ( GBrowse )	Untitled Document
Allele class
Mutagen	P-element activity
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	P-element activity (Fetchko et al., 2002)
Mutations Mapped to the Genome

Type Location Additional Notes References transposable element insertion site 2R:18,205,512..18,205,519 (Melnattur et al., 2002, Fetchko et al., 2002)
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	P{lacW}px^k08134 (Fetchko et al., 2002)
Nature of the lesion	Statement Reference P{lacW} insertion maps to the second intron of the Gp150 transcription unit, 53bp downstream of the second exon. (Fetchko et al., 2002) P-element insertion in the second intron. (Melnattur et al., 2002)
Caused by insertion	P{lacW}Gp150^P8 (Melnattur et al., 2002, Fetchko et al., 2002)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In
	ommatidium (with Gp150^k11120b) (Fetchko et al., 2002)
Detailed Description
	Statement Reference 19.2% of ommatidia in Gp150^P8/Gp150^k11120b animals are mutant. (Fetchko et al., 2002)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhanced by
Statement Reference Gp150^k11120b/Gp150^P8 has ommatidium phenotype, enhanceable by Dl^6B (Fetchko et al., 2002) Gp150^k11120b/Gp150^P8 has ommatidium phenotype, enhanceable by Dl^9P (Fetchko et al., 2002) Gp150^k11120b/Gp150^P8 has ommatidium phenotype, enhanceable by N^55e11 (Fetchko et al., 2002)
Additional Comments
Genetic Interactions
Statement Reference The addition of N^55e11/+ to Gp150^P8/Gp150^k11120b animals increases the proportion of mutant ommatidia from 19.2% to 42.3%. The addition of Dl^9P/+ to Gp150^P8/Gp150^k11120b animals increases the proportion of mutant ommatidia from 19.2% to 67.6%. The addition of Dl^9P/+ to Gp150^P8/Gp150^k11120b animals increases the proportion of mutant ommatidia from 19.2% to 44.6%. (Fetchko et al., 2002)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Phenotype is revertable on excision of the P-element. (Fetchko et al., 2002)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	gp150^P8 (Melnattur et al., 2002) Gp150^P8
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Fetchko et al., 2002, EMBO J. 21(5): 1074--1083 Drosophila Gp150 is required for early ommatidial development through modulation of Notch signaling. [FBrf0144849] Melnattur et al., 2002, genesis 34(1-2): 29--33 P(52A-GAL4) is an insertion in the Drosophila gp150 gene. [FBrf0151713]

Allele Dmel\Gp150P8

Allele Dmel\Gp150^P8