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General Information
Symbol
Dmel\drmunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0141168
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    The 1o-3o fates of the dorsal epidermis are replaced with the 4o fate in mutant embryos.

    In drmunspecified homozygous embryos the proventriculus fails to form and the hindgut is short and wide, with duplicated boundary cell rows. The foregut fails to form the keyhole structure, as indicated by marker analysis and the lack of a gap in the visceral musculature over this region of the gut, and so remains as a narrow tube.

    The hindgut is wider and shorter than normal in mutant embryos. The small intestine is missing, the cells of the large intestine are columnar (resembling the cells of the immature wild-type hindgut primordium) and the boundary cell rows that run along the length of the large intestine are duplicated. The proventriculus does not fold properly.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    NOT Enhancer of
    Statement
    Reference
    NOT Suppressor of
    Statement
    Reference
    Other
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    The dorsal cuticle phenotype of drmunspecified linunspecified double mutant embryos is the same as that of linunspecified single mutant embryos.

    linunspecified; drmunspecified double homozygous embryos have a foregut phenotype identical to those of linunspecified homozygotes (bloated and with an expanded keyhole structure), rather than drmunspecified homozygotes (narrow and lacking a keyhole structure).

    linunspecified drmunspecified double mutant embryos have the same mutant hindgut and foregut phenotypes as linunspecified single mutant embryos.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Partially rescued by

    drmunspecified is partially rescued by drmt18.1

    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    drmunspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (3)