Syx5EP2313 homozygotes exhibit small and irregularly shaped rhabdomeres, and the photoreceptor cells show an accumulation of ER and lipid droplets, as compared to controls.
Expression via Scer\GAL4fkh.PH results in a weakly penetrant 'degenerating glands' phenotype in the embryonic salivary gland.
Syx5EP2313/Syx5AR113 mutant males (with no Scer\GAL4 driver) have no motile sperm and appear to be defective in spermatid elongation. Mutant testes contain predominantly large, oval cysts and a few elongated bundles. Mutant testes also have abnormally large mitochondrial derivatives that are associated with multiple nuclei, indicative of a failure in cytokinesis. Mutant testes also exhibit an accumulation of unusual ovoid spermatid cysts.