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General Information
Symbol
Dmel\Su(var)3-7FL.hs.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0141357
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
HA:FL
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A heat shock promoter drives expression of a 3.4kb cDNA fragment encoding Su(var)3-7 amino acids 37 to 1169. The Su(var)3-7 protein is tagged at the N-terminal end with Tag:HA.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Su(var)3-7FL.hs.T:Ivir\HA1 enhances variegation of w (carried on the P{Winkelried}D insertion) in In(2)Heidi-P{Winkelried}D flies. Expression of Su(var)3-7FL.hs.T:Ivir\HA1 enhances variegation of w in In(1)wm4h.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference
Phenotype Manifest In
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The expression of msl-2Hsp83.PK in females overexpressing Su(var)3-7FL.hs.T:Ivir\HA1 causes the X chromosomes to condense as typically seen only in males overexpressing Su(var)3-7FL.hs.T:Ivir\HA1.

The presence of Su(var)3-7FL.hs.T:Ivir\HA1 suppresses the mle1 phenotype resulting in almost normal male X chromosome morphology.

A Su(var)3-7R2a8 background kills males expressing msl-1Hsp83.PC-msl-2Hsp83.PK. Homozygous Su(var)3-7R2a8 females crossed with transgenic msl-1Hsp83.PC-msl-2Hsp83.PK males produce only 6% of male adult progeny harbouring the transgenes compared to 48% if the mothers are heterozygous for Su(var)3-7R2a8.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Su(var)3-7FL.hs.T:Ivir\HA1
Su(var)3-7FL.hs.Tag:HA
Name Synonyms
Secondary FlyBase IDs
    References (4)