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General Information
Symbol
Dmel\Snr1E1
Species
D. melanogaster
Name
FlyBase ID
FBal0141382
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Comment:
Unspecified mutation in Gly256.
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Amino acid replacement: G256?.
Single amino acid substitution in the conserved Repeat 2 region, implicated in a variety of protein-protein interactions.
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Heterozygotes have ectopic wing vein material perpendicular to the posterior crossvein and anterior to longitudinal vein L2. These defects are seen at the permissive temperature (18[o]), with increased penetrance at the restrictive temperature (29[o]C).
Heterozygotes show a weak extra vein extending distally from the posterior crossvein. Snr1R3/Snr1E1 flies have an extra vein phenotype in the wings, with extra vein material posterior to wing vein L5 and extending distally from the posterior crossvein.
At 29oC, 68% of heterozygous flies have an ectopic vein emanating from the posterior crossvein of the wing and 32% have wild-type wings. Snr1SR21/Snr1E1 adults have extensive disruptions of wing vein patterning at 29oC. Heterozygous and homozygous adults have an increased body mass and wing size at 18oC compared to controls. Homozygous flies have an increased cell number (cells per unit area in the wing) compared to controls. Homozygous stage P3 pupae have a significantly increased body mass compared to control pupae.
Snr1E1 is a temperature-sensitive allele of Snr1. Genetic analyses of Snr1E1 reveal that it functions as an antimorph.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
Snr1E1 has visible | dominant phenotype, enhanceable by Df(3L)AC1/+
Snr1E1 has visible | dominant phenotype, enhanceable by Jarid2[+]/Jarid2EY02717
Snr1E1 has visible | dominant phenotype, enhanceable by Df(3R)by10/+
Snr1E1 has visible | dominant phenotype, enhanceable by JHDM2[+]/JHDM2EY01319
Snr1E1 has visible | dominant phenotype, enhanceable by PSREY07193/PSR[+]
Snr1E1 has visible | dominant phenotype, enhanceable by mor[+]/mor1
Snr1E1 has visible | dominant phenotype, enhanceable by Df(3R)Exel7327/+
Snr1E1 has visible | dominant phenotype, enhanceable by mor3/mor[+]
Snr1E1 has visible | dominant phenotype, enhanceable by mor5/mor[+]
Snr1E1 has visible | dominant phenotype, enhanceable by mor6/mor[+]
Snr1E1 has visible | dominant phenotype, enhanceable by Df(3L)81k19/+
Snr1E1 has visible | dominant phenotype, enhanceable by aos[+]/aosΔ7
Snr1E1 has visible | dominant phenotype, enhanceable by aos[+]/aos05845
Snr1E1 has visible | dominant phenotype, enhanceable by Df(3L)vin5/+
Snr1E1 has visible | dominant phenotype, enhanceable by Df(3L)vin7/+
Snr1E1 has visible | dominant phenotype, enhanceable by HDAC3B/Hdac3[+]
Snr1E1 has visible | dominant phenotype, enhanceable by HDAC3N/Hdac3[+]
Snr1E1 has visible | dominant phenotype, enhanceable by HDAC104556/Rpd3[+]
Snr1E1 has visible | dominant phenotype, enhanceable by HDAC15-5/Rpd3[+]
NOT Enhanced by
Statement
Reference
Snr1E1 has visible | dominant phenotype, non-enhanceable by Su(var)3-3[+]/Su(var)3-3ΔN
Snr1E1 has visible | dominant phenotype, non-enhanceable by lid2REV/lid[+]
Snr1E1 has visible | dominant phenotype, non-enhanceable by Kdm4A[+]/Kdm4AKG04636
Snr1E1 has visible | dominant phenotype, non-enhanceable by CG10133[+]/JMJD7KG04150
Snr1E1 has visible | dominant phenotype, non-enhanceable by Jarid2[+]/Jarid2EY02717-REV
Snr1E1 has visible | dominant phenotype, non-enhanceable by Df(1)19/+
Suppressed by
Statement
Reference
Snr1E1 has visible | dominant phenotype, suppressible by Df(2L)BSC206/+
Snr1E1 has visible | dominant phenotype, suppressible by Df(3R)Exel6151/+
Snr1E1 has visible | dominant phenotype, suppressible by Kdm2[+]/Kdm2DG12810
Snr1E1 has visible | dominant phenotype, suppressible by brm[+]/brm2
Snr1E1 has visible | dominant phenotype, suppressible by mor2/mor[+]
Snr1E1 has visible | dominant phenotype, suppressible | partially by mor[+]/mor4
Snr1E1 has visible | dominant phenotype, suppressible by Df(2R)CX1/+
Snr1E1 has visible | dominant phenotype, suppressible by E(Egfr)B56[+]/E(Egfr)B56B56
Snr1E1 has visible | dominant phenotype, suppressible by Df(2L)ED354/+
Snr1E1 has visible | dominant phenotype, suppressible by lid[+]/lid10424
Snr1E1 has visible | dominant phenotype, suppressible by lidk06801/lid[+]
Snr1E1 has visible | dominant phenotype, suppressible by Df(2R)Exel6055/+
Snr1E1 has visible | dominant phenotype, suppressible by Df(2R)Exel8057/+
Snr1E1 has visible | dominant phenotype, suppressible by Df(2L)BSC149/+
Snr1E1 has visible | dominant phenotype, suppressible by JMJD5e01240/CG13902[+]
Snr1E1 has visible | dominant phenotype, suppressible by Df(3L)ED4177/+
Snr1E1 has visible | dominant phenotype, suppressible by Df(3L)Exel6119/+
Snr1E1 has visible | dominant phenotype, suppressible by Df(3R)Exel6190/+
Snr1E1 has visible | dominant phenotype, suppressible by Df(1)ED6720/+
Snr1E1 has visible | dominant phenotype, suppressible by CG2982[+]/NO66EP1316
HDAC3B, Snr1E1/Snr1[+] has visible | dominant phenotype, suppressible | partially by brm2
HDAC104556, Snr1E1/Snr1[+] has visible | dominant phenotype, suppressible | partially by brm2
Snr1E1 has visible | dominant phenotype, suppressible by Cdk23/cdc2c[+]
Snr1E1 has visible | dominant phenotype, suppressible | partially by cdc2c[+]/Cdk21
Snr1E1 has visible phenotype, suppressible | partially by Df(2L)osp29/+
Snr1E1 has visible | dominant phenotype, suppressible | partially by CycEJP/CycEJP
NOT suppressed by
Statement
Reference
Snr1E1 has visible | dominant phenotype, non-suppressible by Su(var)3-3[+]/Su(var)3-3ΔN
Snr1E1 has visible | dominant phenotype, non-suppressible by lid2REV/lid[+]
Snr1E1 has visible | dominant phenotype, non-suppressible by Kdm4A[+]/Kdm4AKG04636
Snr1E1 has visible | dominant phenotype, non-suppressible by CG10133[+]/JMJD7KG04150
Snr1E1 has visible | dominant phenotype, non-suppressible by Jarid2[+]/Jarid2EY02717-REV
Snr1E1 has visible | dominant phenotype, non-suppressible by Df(1)19/+
Enhancer of
Statement
Reference
Snr1E1/Snr1[+] is an enhancer of visible | dominant phenotype of HDAC3B
Suppressor of
Statement
Reference
Snr1E1/Snr1[+] is a suppressor of visible phenotype of Scer\GAL469B, brmK804R.UAS.Tag:HA
Snr1E1 is a suppressor of visible phenotype of CycEJP
Other
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference
Snr1E1 has wing vein | ectopic phenotype, enhanceable by Df(3L)AC1/+
Snr1E1 has wing vein | ectopic phenotype, enhanceable by Jarid2[+]/Jarid2EY02717
Snr1E1 has wing vein | ectopic phenotype, enhanceable by Df(3R)by10/+
Snr1E1 has wing vein | ectopic phenotype, enhanceable by JHDM2[+]/JHDM2EY01319
Snr1E1 has wing vein | ectopic phenotype, enhanceable by PSREY07193/PSR[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by mor[+]/mor1
Snr1E1 has wing vein | ectopic phenotype, enhanceable by Df(3R)Exel7327/+
Snr1E1 has wing vein | ectopic phenotype, enhanceable by mor3/mor[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by mor5/mor[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by mor6/mor[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by Df(3L)81k19/+
Snr1E1 has wing vein | ectopic phenotype, enhanceable by aos[+]/aosΔ7
Snr1E1 has wing vein | ectopic phenotype, enhanceable by aos[+]/aos05845
Snr1E1 has wing vein | ectopic phenotype, enhanceable by RpII215[+]/RpII2153
Snr1E1 has wing vein | ectopic phenotype, enhanceable by RpII215[+]/RpII2158
Snr1E1 has wing vein | ectopic phenotype, enhanceable by ab1/ab[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by ash1[+]/ash117
Snr1E1 has wing vein | ectopic phenotype, enhanceable by ash1[+]/ash122
Snr1E1 has wing vein | ectopic phenotype, enhanceable by bs03267/bs[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by bs[+]/bs2
Snr1E1 has wing vein | ectopic phenotype, enhanceable by bs[+]/bsk07909
Snr1E1 has wing vein | ectopic phenotype, enhanceable by corto07128b/corto[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by corto[+]/cortol1
Snr1E1 has wing vein | ectopic phenotype, enhanceable by cortotsT18/corto[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by cv1/cv[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by ex697/ex[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by groC105/gro[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by kis[+]/kis1
Snr1E1 has wing vein | ectopic phenotype, enhanceable by kisk13416/kis[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by lawc[+]/lawcEF250
Snr1E1 has wing vein | ectopic phenotype, enhanceable by net1/net[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by px[+]/px72
Snr1E1 has wing vein | ectopic phenotype, enhanceable by sbb[+]/sbb04440
Snr1E1 has wing vein | ectopic phenotype, enhanceable by Df(2L)net62/+
Snr1E1 has wing vein | ectopic phenotype, enhanceable by Df(2R)Px2/+
Snr1E1 has wing vein | ectopic phenotype, enhanceable by +/Df(3R)6-7
Snr1E1 has wing vein | ectopic phenotype, enhanceable by E(z)[+]/E(z)60
Snr1E1 has wing vein | ectopic phenotype, enhanceable by Egfr[+]/EgfrE1
Snr1E1 has wing vein | ectopic phenotype, enhanceable by Hsc70-403550/Hsc70-4[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by Df(3L)vin5/+
Snr1E1 has wing phenotype, enhanceable by Df(3L)vin5/+
Snr1E1 has wing vein | ectopic phenotype, enhanceable by Df(3L)vin7/+
Snr1E1 has wing phenotype, enhanceable by Df(3L)vin7/+
Snr1E1 has wing vein | ectopic phenotype, enhanceable by HDAC3B/Hdac3[+]
Snr1E1 has wing phenotype, enhanceable by HDAC3B/Hdac3[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by HDAC3N/Hdac3[+]
Snr1E1 has wing phenotype, enhanceable by HDAC3N/Hdac3[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by HDAC104556/Rpd3[+]
Snr1E1 has wing phenotype, enhanceable by HDAC104556/Rpd3[+]
Snr1E1 has wing vein | ectopic phenotype, enhanceable by HDAC15-5/Rpd3[+]
Snr1E1 has wing phenotype, enhanceable by HDAC15-5/Rpd3[+]
NOT Enhanced by
Statement
Reference
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Su(var)3-3[+]/Su(var)3-3ΔN
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by lid2REV/lid[+]
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Kdm4A[+]/Kdm4AKG04636
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by CG10133[+]/JMJD7KG04150
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Jarid2[+]/Jarid2EY02717-REV
Snr1R3/Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by ash14
Snr1R3/Snr1E1 has wing phenotype, non-enhanceable by ash14
Snr1R3/Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by trxE2
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Dll5/Dll[+]
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Dll9/Dll[+]
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by E(spl)[+]/E(spl)m8-HLH1
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Me[+]/Me1
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Pcl[+]/Pcl11
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by RpII215[+]/RpII2151
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Sce[+]/SceD1
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by ScmD1/Scm[+]
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Scr[+]/Scr17
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Scr[+]/Scr7
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Su(z)21.a1/Su(z)2[+]
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Taf1[+]/Taf11
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Taf1[+]/Taf1EP421/Scer\GAL4[-]
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Taf1[+]/Taf1XS-2232
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by bs[+]/bs1348
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by en[+]/en4
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by gro1/gro[+]
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by kni[+]/kniri-1
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by lawcp1/lawc[+]
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by sd[+]/sd1
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by tkvk16713/tkv[+]
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by trx[+]/trx1
Snr1E1 has wing vein | ectopic phenotype, non-enhanceable by Df(1)19/+
Snr1E1 has wing phenotype, non-enhanceable by Df(1)19/+
Suppressed by
Statement
Reference
Snr1E1 has wing vein | ectopic phenotype, suppressible by Df(2L)BSC206/+
Snr1E1 has wing vein | ectopic phenotype, suppressible by Df(3R)Exel6151/+
Snr1E1 has wing vein | ectopic phenotype, suppressible by Kdm2[+]/Kdm2DG12810
Snr1E1 has wing vein | ectopic phenotype, suppressible by brm[+]/brm2
Snr1E1 has wing vein | ectopic phenotype, suppressible by mor2/mor[+]
Snr1E1 has wing vein | ectopic phenotype, suppressible | partially by mor[+]/mor4
Snr1E1 has wing vein | ectopic phenotype, suppressible by Df(2R)CX1/+
Snr1E1 has wing vein | ectopic phenotype, suppressible by E(Egfr)B56[+]/E(Egfr)B56B56
Snr1E1 has wing vein | ectopic phenotype, suppressible by Df(2L)ED354/+
Snr1E1 has wing vein | ectopic phenotype, suppressible by lid[+]/lid10424
Snr1E1 has wing vein | ectopic phenotype, suppressible by lidk06801/lid[+]
Snr1E1 has wing vein | ectopic phenotype, suppressible by Df(2R)Exel6055/+
Snr1E1 has wing vein | ectopic phenotype, suppressible by Df(2R)Exel8057/+
Snr1E1 has wing vein | ectopic phenotype, suppressible by Df(2L)BSC149/+
Snr1E1 has wing vein | ectopic phenotype, suppressible by JMJD5e01240/CG13902[+]
Snr1E1 has wing vein | ectopic phenotype, suppressible by Df(3L)ED4177/+
Snr1E1 has wing vein | ectopic phenotype, suppressible by Df(3L)Exel6119/+
Snr1E1 has wing vein | ectopic phenotype, suppressible by Df(3R)Exel6190/+
Snr1E1 has wing vein | ectopic phenotype, suppressible by Df(1)ED6720/+
Snr1E1 has wing vein | ectopic phenotype, suppressible by CG2982[+]/NO66EP1316
Snr1E1 has wing vein | ectopic phenotype, suppressible by Asx[+]/Asx1
Snr1E1 has wing vein | ectopic phenotype, suppressible by Df(3L)iro-2/+
Snr1E1 has wing vein | ectopic phenotype, suppressible by NAx-tsl/N[+]
Snr1E1 has wing vein | ectopic phenotype, suppressible by S[+]/S1
Snr1E1 has wing vein | ectopic phenotype, suppressible by brm2
Snr1E1 has wing vein | ectopic phenotype, suppressible by gpp[+]/gpp61A
Snr1E1 has wing vein | ectopic phenotype, suppressible by gpp[+]/gpp94A
Snr1E1 has wing vein | ectopic phenotype, suppressible by gpp[+]/gppXXV
Snr1E1 has wing vein | ectopic phenotype, suppressible by sensLy-1/sens[+]
Snr1R3/Snr1E1 has wing vein | ectopic phenotype, suppressible by dpps1/dpps1
Snr1E1 has wing vein | ectopic phenotype, suppressible by ash1[+]/ash117
Snr1E1 has wing vein | ectopic phenotype, suppressible by ash1[+]/ash122
HDAC104556, Snr1E1/Snr1[+] has wing vein | ectopic phenotype, suppressible | partially by brm2
HDAC104556, Snr1E1/Snr1[+] has wing phenotype, suppressible | partially by brm2
Snr1E1 has wing vein | ectopic phenotype, suppressible by Cdk23/cdc2c[+]
Snr1E1 has wing phenotype, suppressible by Cdk23/cdc2c[+]
Snr1E1 has wing vein | ectopic phenotype, suppressible | partially by cdc2c[+]/Cdk21
Snr1E1 has wing phenotype, suppressible | partially by cdc2c[+]/Cdk21
Snr1E1 has wing vein | ectopic phenotype, suppressible | partially by Df(2L)osp29/+
Snr1E1 has wing phenotype, suppressible | partially by Df(2L)osp29/+
Snr1E1 has wing vein | ectopic phenotype, suppressible | partially by CycEJP/CycEJP
Snr1E1 has wing phenotype, suppressible | partially by CycEJP/CycEJP
NOT suppressed by
Statement
Reference
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Su(var)3-3[+]/Su(var)3-3ΔN
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by lid2REV/lid[+]
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Kdm4A[+]/Kdm4AKG04636
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by CG10133[+]/JMJD7KG04150
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Jarid2[+]/Jarid2EY02717-REV
Snr1R3/Snr1E1 has wing vein | ectopic phenotype, non-suppressible by ash14
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Dll9/Dll[+]
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by E(spl)[+]/E(spl)m8-HLH1
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Me[+]/Me1
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Pcl[+]/Pcl11
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by RpII215[+]/RpII2151
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Sce[+]/SceD1
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by ScmD1/Scm[+]
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Scr[+]/Scr17
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Scr[+]/Scr7
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Su(z)21.a1/Su(z)2[+]
Snr1R3/Snr1E1 has wing phenotype, non-suppressible by ash14
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Taf1[+]/Taf11
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Taf1[+]/Taf1EP421/Scer\GAL4[-]
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Taf1[+]/Taf1XS-2232
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by bs[+]/bs1348
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by en[+]/en4
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by gro1/gro[+]
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by kni[+]/kniri-1
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by lawcp1/lawc[+]
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by sd[+]/sd1
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by tkvk16713/tkv[+]
Snr1R3/Snr1E1 has wing vein | ectopic phenotype, non-suppressible by trxE2
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by trx[+]/trx1
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Dll5/Dll[+]
Snr1E1 has wing vein | ectopic phenotype, non-suppressible by Df(1)19/+
Snr1E1 has wing phenotype, non-suppressible by Df(1)19/+
Enhancer of
Statement
Reference
Snr1E1 is an enhancer of wing vein phenotype of Dl6B
Snr1E1/Snr1E1 is an enhancer of wing vein phenotype of tkv1
Snr1E1/Snr1[+] is an enhancer of wing vein phenotype of tkv1
Snr1R3/Snr1E1 is an enhancer of wing vein phenotype of Dl9P
Snr1E1 is an enhancer of wing vein phenotype of Dl9P
Snr1E1/Snr1[+] is an enhancer of wing vein | ectopic phenotype of net1
Snr1R3/Snr1E1 is an enhancer of wing vein phenotype of dpps1
Snr1E1/Snr1[+] is an enhancer of wing vein | ectopic phenotype of HDAC3B
Snr1E1/Snr1[+] is an enhancer of wing phenotype of HDAC3B
NOT Enhancer of
Statement
Reference
Snr1E1 is a non-enhancer of eye phenotype of S1
Suppressor of
Statement
Reference
Snr1E1 is a suppressor of wing vein L4 phenotype of H2
Snr1E1 is a suppressor of wing vein L5 phenotype of brm2, rhove-1
Snr1R3/Snr1E1 is a suppressor of wing vein L5 phenotype of rhove-1
Snr1E1 is a suppressor of eye phenotype of CycEJP
Snr1E1 is a suppressor of wing phenotype of CycEJP
NOT Suppressor of
Statement
Reference
Snr1E1 is a non-suppressor of eye phenotype of S1
Other
Additional Comments
Genetic Interactions
Statement
Reference
Df(2R)CX1 dominantly suppresses the ectopic wing vein phenotype seen in Snr1E1/+ animals, and the double heterozygotes also show minor notching of posterior and distal parts of the wing blade.
The loss of wing vein L5 and the posterior crossvein seen in animals expressing brmK804R.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL469B at 18oC is suppressed by Snr1E1/+. At 29oC, ash117 suppresses the ectopic vein that extends distally from the posterior crossvein in Snr1E1 animals. but enhances the extra vein material seen posterior of the L5 wing vein. At 29oC, ash122 suppresses the ectopic vein that extends distally from the posterior crossvein in Snr1E1 animals. but enhances the extra vein material seen posterior of the L5 wing vein. 18% of Hsc70-4L3929/Snr1E1 animals have an incomplete L5 wing vein. Pc4/Snr1E1 animals have incomplete L3, L4 and L5 wing veins (9%, 42% and 37% respectively) and moderate curling and disruption of the wing along the posterior wing margin. Pc1/Snr1E1 animals have incomplete L2, L4 and L5 wing veins (6%, 38% and 22% respectively) and moderate curling and disruption of the wing along the posterior wing margin. Psce22/Snr1E1 wings have an extra vein between veins L3 and L4 in 44% of cases. Asx1/Snr1E1 wings have an extra vein between veins L3 and L4 in 11% of cases. vnC221/Snr1E1 animals show an incomplete or deleted anterior crossvein in 15% of wings. The Dl9P thick vein phenotype is enhanced by Snr1E1, especially near the distal tips of veins L3, L4 and L5. The Dl9P thick vein phenotype is enhanced by Snr1E1/Snr1R3. The Dl6B thick vein phenotype is enhanced by Snr1E1, especially near the distal tips of veins L3, L4 and L5. dpps1/dpps1 Snr1E1/Snr1R3 animals show suppression of the Snr1 extra wing vein phenotype and enhancement of the dpp loss of vein phenotype in L5. The incomplete L4 wing vein phenotype seen in H2 mutants is suppressed by Snr1E1. The dominant rough eye phenotype caused by S1 is not affected if Snr1E1 is also present. Snr1E1/Snr1R3 suppresses the loss of wing vein L5 seen in rhove-1 homozygotes and rhove-1 suppresses the Snr1E1/Snr1R3 extra wing vein phenotype. Snr1E1 suppresses the shortened L5 wing vein that results from the interaction between rhove-1 and brm2.
At 29oC, CycEJP/CycEJP suppresses the ectopic wing vein phenotype of Snr1E1/+; 12% of flies have an ectopic vein emanating from the posterior crossvein and 88% have wild-type wings. At 29oC, Df(2L)osp29/+ suppresses the ectopic wing vein phenotype of Snr1E1; 31% of flies have an ectopic vein emanating from the posterior crossvein and 69% have wild-type wings. The eye and wing phenotypes of CycEJP are suppressed in a dosage- and temperature-dependent manner by Snr1E1. At 29oC, cdc2c1/+ suppresses the ectopic wing vein phenotype of Snr1E1/+; 15% of flies have an ectopic vein emanating from the posterior crossvein and 85% have wild-type wings. At 29oC, cdc2c3/+ suppresses the ectopic wing vein phenotype of Snr1E1/+; 100% of the flies have wild-type wings. At 29oC, Rpd35-5/+ enhances the ectopic wing vein phenotype of Snr1E1/+; 8% of flies have ectopic veins emanating from the posterior crossvein and posterior to the L5 longitudinal vein. At 29oC, Rpd304556/+ enhances the ectopic wing vein phenotype of Snr1E1/+; 61% have an ectopic vein emanating from the posterior crossvein and 39% of flies have ectopic veins emanating from the posterior crossvein and posterior to the L5 longitudinal vein. The ectopic wing vein phenotype seen in Rpd304556/Snr1E1 and Hdac3N/Snr1E1 double heterozygotes at 29oC is partially suppressed by brm2/+. At 29oC, Hdac3N/+ enhances the ectopic wing vein phenotype of Snr1E1/+; 100% of flies have ectopic veins emanating from the posterior crossvein and posterior to the L5 longitudinal vein. At 29oC, Hdac3B/Snr1E1 double heterozygotes have an ectopic wing vein phenotype; 5% have normal wings, 58% have an ectopic vein emanating from the posterior crossvein and 37% have ectopic veins emanating from the posterior crossvein and posterior to the L5 longitudinal vein.
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