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General Information
Symbol
Dmel\S6kTE.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0141551
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-s6kTE, UAS-S6K-TE, UAS-dS6KTE, UAS-S6K
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of a mutated form of S6k (carries the amino acid replacement T398E).

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression via Scer\GAL4wor.PA and Scer\GAL80ase.PN does not prevent the normal shrinkage and disappearance of pupal neuroblasts.

Expression of S6kTE.Scer\UAS using Scer\GAL4nub-AC-62 results in abnormally large wings in which cell size is increased.

Expression of S6kTE.Scer\UAS under the control of Scer\GAL4elav.PLu has little effect on neuromuscular junction growth.

After 30 days of light/dark cycling, photoreceptors are preserved normally in Scer\GAL4GMR.PU driven S6kTE.Scer\UAS flies.

Expression of S6kTE.Scer\UAS under the control of Scer\GAL4ap-md544 results in wings which bend down (the wings bend down more than in flies expressing S6kScer\UAS.cMa under the control of Scer\GAL4ap-md544).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference

The co-expression of LamCUAS.cSa and S6kTE.UAS under the control of Scer\GAL4fln.IFM under the control of Scer\GAL4fln.IFM does not lead to any obvious indirect flight muscle, wing posture or flight defects.

Co-expression of S6kTE.Scer\UAS diminishes the small wing and decreased wing cell size phenotypes seen in hppyScer\UAS.cMa, Scer\GAL4nub-AC-62 wings.

Co-expression of S6kTE.Scer\UAS under the control of Scer\GAL4elav.PLu, fails to suppress the neuromuscular junction overgrowth phenotype found upon expression of Atg1Scer\UAS.cSa.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
S6kTE.Scer\UAS
S6kTE.UAS
Name Synonyms
Secondary FlyBase IDs
    References (16)