A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Allele Dmel\IncenpdsRNA.cTa

General Information
SymbolDmel\IncenpdsRNA.cTaSpeciesD. melanogaster
NameFlyBase IDFBal0141669
Feature typealleleAssociated geneDmel\Incenp
Allele class
Mutagenin vitro construct - RNAi
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Description
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FB2013_03
FB2013_02
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Allele class
Mutagen
Mutations Mapped to the Genome
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Progenitor genotype
Nature of the lesion
Statement
Reference
Construct: Template corresponding to 700bp fragment of Incenp cDNA.
Cytology
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Statement
Reference
SL2 cells treated with IncenpdsRNA.cTa dsRNA and cultured for 4 days show a significant increase in 4N cells at the expense of 2N cells when compared to controls. 38.5% of the cell population corresponds to cells with a DNA content of 8N. The cells treated with IncenpdsRNA.cTa dsRNA are larger than control cells.
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Comments
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Discoverer
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dsRNA has been synthesised from the template and added to the culture medium of SL2 cells to study the phenotypic consequences of dsRNA interference (RNAi) of the Incenp gene.
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Reported As
Symbol Synonym
IncenpdsRNA.cTa
 
Name Synonym
Secondary FlyBase IDs
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Research paper
Tseng and Hariharan, 2002, Genetics 162(1): 229--243
An overexpression screen in Drosophila for genes that restrict growth or cell-cycle progression in the developing eye. [FBrf0152035]