FB2025_01 , released February 20, 2025
Allele: Dmel\IP3K1UAS.cMa
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General Information
Symbol
Dmel\IP3K1UAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Monnier
FlyBase ID
FBal0141722
Feature type
allele
Associated gene
Dmel\IP3K1
Associated Insertion(s)
Carried in Construct
P{UAS-IP3K1.M}
Key Links
Transgenic product class
cDNA
(Monnier et al., 2002)
wild_type
(Monnier et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Monnier et al., 2002)
wild_type
(Monnier et al., 2002)
Mutagen
in vitro construct
(Monnier et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-IP3K1.M}
Cytology
Description

UASt regulatory sequences drive expression of the full length IP3K1 EST SD07279.

(Monnier et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
IP3K1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of IP3K1Scer\UAS.cMa under the control of Scer\GAL4Uro.PT significantly reduces survival upon oxidative stress challenge by H[[2]]O[[2]] compared to controls.

      H[[2]]O[[2] production in isolated Malpighian tubules expressing IP3K1Scer\UAS.cMa under the control of Scer\GAL4Uro.PT is significantly increased compared to controls.

      (Terhzaz et al., 2010)

      Expression of IP3K1Scer\UAS.cMa under the control of Scer\GAL4da.G32 results in an increased resistance to 1% H2O2 compared to control flies. Flies expressing IP3K1Scer\UAS.cMa under the control of Scer\GAL4da.G32 show no significant difference in resistance to paraquat compared to control flies.

      (Monnier et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      IP3K1Scer\UAS.cMa
      IP3K1UAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Monnier
      (Monnier et al., 2002)
      Secondary FlyBase IDs
        References (2)