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General Information
Symbol
Dmel\Apc2UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0141949
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-APC2-GFP, Apc2-GFP
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of Apc2 tagged with GFP.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Apc2Scer\UAS.T:Avic\GFP under the control of Scer\GAL4pros.PMG has no effect on overall brain morphology.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
NOT Suppressor of
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The formation of supernumerary neuroblasts which is seen in clones derived from single type II neuroblasts expressing kluScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4wor.PA is suppressed if the clones are also co-expressing Apc2Scer\UAS.T:Avic\GFP.

Expression of Apc2Scer\UAS.T:Avic\GFP in germ cells under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 suppresses the germline stem cell (GSC) loss seen in chic11/chic01320 mutant testes.

Expression of Apc2Scer\UAS.T:Avic\GFP in germ cells under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 does not suppress the germline stem cell (GSC) loss seen in chic221/chic01320 mutant testes.

Expression of Apc2Scer\UAS.T:Avic\GFP under the control of Scer\GAL4da.G32 has no effect on the ventral denticle belt phenotype of the germ-line and zygotic AxnS044230-mutation.

Expression of Apc2Scer\UAS.T:Avic\GFP under the control of Scer\GAL4da.G32 restores wild-type patterning of the ventral cuticle in ApcQ8, Apc2d40 double mutant embryos.

Expression of Apc2Scer\UAS.T:Avic\GFP under the control of Scer\GAL4da.G32 has no effect on the ventral denticle belt phenotype of AxnS044230, ApcQ8, Apc2d40 triple mutants.

Expression of Apc2Scer\UAS.T:Avic\GFP has no effect on the ventral denticle belt phenotype of sggM11 mutant embryos.

Expression of both ApcScer\UAS.cHa and Apc2Scer\UAS.T:Avic\GFP under the control of Scer\GAL4pros.PMG has no effect on overall brain morphology.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments

Expression of Apc2Scer\UAS.T:Avic\GFP under the control of Scer\GAL4arm.PS rescues Apc2N175K flies through to adulthood, although their viability is poor.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

R. Rosin-Arbesfeld M. Bienz

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Apc2Scer\UAS.T:Avic\GFP
Apc2UAS.GFP
Name Synonyms
Secondary FlyBase IDs
    References (18)