Allele Dmel\robl^MB

General Information
Symbol	Dmel\robl^MB	Species	D. melanogaster
Name		FlyBase ID	FBal0143259
Feature type	allele	Associated gene	Dmel\robl

Allele class
Mutagen	ethyl methanesulfonate
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	ethyl methanesulfonate (Reuter et al., 2003)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	decreased cell number \| somatic clone (Reuter et al., 2003) neuroanatomy defective \| recessive \| somatic clone \| third instar larval stage (Satoh et al., 2008) neuroanatomy defective \| somatic clone (Reuter et al., 2003)
Phenotype Manifest In
	adult mushroom body \| somatic clone (Reuter et al., 2003) class IV dendritic arborizing neuron \| somatic clone \| third instar larval stage (Satoh et al., 2008) dendrite \| third instar larval stage (Satoh et al., 2008) larval mushroom body \| somatic clone (Reuter et al., 2003)
Detailed Description
	Statement Reference Homozygous robl[MB] mutant neurons in the third instar larva display abnormal dendritic arborization. (Satoh et al., 2008) Homozygous mushroom body neuroblast clones generated in newly hatched larvae and examined in the wandering third instar or single cell mushroom body neuron clones show a "spotty axon" phenotype; the mutant cells have periodic swellings along their axons or near the axon terminals. Homozygous mushroom body neuroblast clones examined in adults are mostly composed of γ neurons. Mutant mushroom body neuroblast clones generated in newly hatched larvae and examined in the wandering third instar have a reduced cell number compared to control clones. (Reuter et al., 2003)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to complement	robl^B (Reuter et al., 2003) robl^Z (Reuter et al., 2003)
Comments
Stocks ( 1 )
Bloomington	8787 w^*; P{FRT(w^hs)}G13 robl^MB/CyO
Notes on Origin
Discoverer
	Separable from: a second lethal mutation on the chromosome (at 46E1--46F2). (Reuter et al., 2003)
External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	7A11 (Reuter et al., 2003) robl^MB
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Satoh et al., 2008, Nat. Cell Biol. 10(10): 1164--1171 Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes. [FBrf0207048] Reuter et al., 2003, Development 130(6): 1203--1213 A mosaic genetic screen for genes necessary for Drosophila mushroom body neuronal morphogenesis. [FBrf0155698]

Allele Dmel\roblMB

Allele Dmel\robl^MB