FB2025_01 , released February 20, 2025
Allele: Dmel\Der-1SH1964
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General Information
Symbol
Dmel\Der-1SH1964
Species
D. melanogaster
Name
FlyBase ID
FBal0143544
Feature type
allele
Associated gene
Dmel\Der-1
Associated Insertion(s)
P{lacW}Der-1SH1964
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Liang et al., 2014)
Mutagen
P-element activity
(Oh et al., 2003)
Progenitor genotype
Associated Insertion(s)
P{lacW}Der-1SH1964
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adulthood-induced Der-1SH1964 homozygous clones in mosaic midguts are larger (i.e. with more cells) and contain increased numbers of stem cells, as compared to control clones.

      (Liu et al., 2022)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Other
      Statement
      Reference

      Der-1SH1964/l(2)SH1964[+], Scer\GAL4GMR.PF, TER94UAS.cCa has visible phenotype

      (Liang et al., 2014)
      Phenotype Manifest In
      Suppressed by
      Other
      Statement
      Reference

      Der-1SH1964/l(2)SH1964[+], Scer\GAL4GMR.PF, TER94UAS.cCa has eye phenotype

      (Liang et al., 2014)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of TER94Scer\UAS.cCa under the control of Scer\GAL4GMR.PF in a heterozygous Der-1SH1964 mutant background results in a rough eye phenotype.

      (Liang et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Der-11
      (Liu et al., 2022)
      Der-1SH1964
      (Liu et al., 2022)
      l(2)SH1964SH1964
      Name Synonyms
      derlin-1l(2)SH1964
      (Liang et al., 2014)
      derlin-1null
      (Liang et al., 2014)
      Secondary FlyBase IDs
        References (3)