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General Information
Symbol
Dmel\mir-banL1170a
Species
D. melanogaster
Name
FlyBase ID
FBal0144427
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
banL1170, ban-lacZ, bantam-lacZ
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{lacW}mir-banL1170a
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

banL1170a homozygotes or banL1170a/Df(3L)banΔ1 hemizygotes survive to adulthood and show wild-type levels of apoptosis. Imaginal discs in banL1170a homo- and hemizygotes or banEP3622/banL1170a transheterozygotes show significantly higher levels of AO staining than wild-type, indicating that these mutants undergo IR-induced apoptosis more readily than wild-type.

banL1170a/banEP3622 mutant germline stem cells (GSCs) show maintenance and cell division defects when clones are generated during adult stages. When banL1170a/banEP3622 clones are generated in larval and pupal stages the GSC loss is less severe.

banL1170a/Df(3L)banΔ1 mutant germline stem cells (GSCs) show maintenance and cell division defects when clones are generated during adult stages. When banL1170a/Df(3L)banΔ1 clones are generated in larval and pupal stages the GSC loss is less severe.

The body mass of banL1170a/Df(3L)banΔ1 adults is only 85% of that of control flies. The wing blade area of banL1170a/Df(3L)banΔ1 flies is only 87% of that of controls. This decrease is entirely due to a decrease in the number of cells, and is not due to a decrease in cell size.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

mir-banL1170a has radiation sensitive phenotype, enhanceable by TieExel9028/Tie[+]

mir-banL1170a has radiation sensitive phenotype, enhanceable by Tiee03394/Tie[+]

mir-banL1170a has radiation sensitive phenotype, enhanceable by Tie[+]/TieC098

mir-banL1170a has radiation sensitive phenotype, enhanceable by Tiee02680/Tie[+]

Suppressed by
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

EP3219EP3219 combined with banL1170a has little or no effect on growth.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer

Separable from: l(3)L1170bL1170b. The P{lacW}banL1170a insertion (which causes a size reduction phenotype) is separable from the lethality of the "l(3)L1170" chromosome (which is caused by l(3)L1170bL1170b).

Comments
Comments

Precise excision of the P{lacW}banL1170a element completely reverts the size reduction and female sterility phenotypes.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (5)