Allele Scer\GAL4^{Orco.2.642.T:Hsim\VP22}

General Information
Symbol	Scer\GAL4^{Orco.2.642.T:Hsim\VP22}	Species	S. cerevisiae
Name		FlyBase ID	FBal0144592
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02	Controlled Vocabulary Terms learning defective adult stage
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Wang et al., 2003)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: A 2.642kb genomic fragment corresponding to the upstream region of the gene Or83b drives expression of Scer\GAL4. The Scer\GAL4 is tagged with T:Hsim\VP22. (Wang et al., 2003)
Carried in construct	P{Orco-GAL4.W} (Fishilevich et al., 2005, Libert et al., 2007, Xu et al., 2008, Wang et al., 2003, Kamikouchi et al., 2006, Tanoue et al., 2004, Tanoue et al., 2008, Suh et al., 2004, Larsson et al., 2004, Shang et al., 2007, Ganguly-Fitzgerald et al., 2006, Benton et al., 2006, Benton et al., 2007, Sweeney et al., 2011, Boto et al., 2010, Hartl et al., 2011, Fujii et al., 2007, Lai and Lee, 2006, Wang and Anderson, 2010, Kain et al., 2008, Root et al., 2008, Masuda-Nakagawa et al., 2009, Bellmann et al., 2010, Olsen et al., 2007, Gomez-Marin et al., 2011, Plavicki et al., 2012, Masuyama et al., 2012, Eddison et al., 2012)
Tagged with	T:Hsim\VP22 (Wang et al., 2003, Tanoue et al., 2004, Suh et al., 2004, Larsson et al., 2004, Manoli et al., 2005, Fishilevich et al., 2005)
Cytology
Phenotypic Data
Phenotypic Class
	chemosensitive behavior defective, with Dll^JF02499 (Plavicki et al., 2012) circadian rhythm defective, with Clk^{Δ.Scer\UAS.T:Ivir\HA1} (Tanoue et al., 2004) circadian rhythm defective, with cyc^{Δ.Scer\UAS.T:Hsap\MYC} (Tanoue et al., 2004) courtship behavior defective, with fru^{dsRNA.M.Scer\UAS} (Manoli et al., 2005) courtship behavior defective, with GABA-B-R2^{dsRNA.Scer\UAS} (Root et al., 2008) feeding behavior defective, with Clk^DN.Scer\UAS (Xu et al., 2008) increased cell death, with Cbβ\DT-A^I.Scer\UAS (Fishilevich et al., 2005) learning defective \| adult stage, with Ctet\TeTxLC^TNT.Scer\UAS (Eddison et al., 2012) learning defective \| adult stage, with for^Scer\UAS.T1 (Eddison et al., 2012) neuroanatomy defective, with Cbβ\DT-A^I.Scer\UAS (Sweeney et al., 2011) neurophysiology defective, with GABA-B-R2^{dsRNA.Scer\UAS} (Root et al., 2008) neurophysiology defective, with Gprk2^Scer\UAS.cTa (Tanoue et al., 2008) neurophysiology defective, with Gαq^{dsRNA.Scer\UAS.1f1} (Kain et al., 2008) neurophysiology defective, with Plc21C^GD11359 (Kain et al., 2008) neurophysiology defective, with rdgA^GD1518 (Kain et al., 2008) phototaxis defective, with Crei\ChR2^Scer\UAS.cSa (Bellmann et al., 2010) phototaxis defective, with Zzzz\PACα^{Scer\UAS.cSLa} (Bellmann et al., 2010) smell perception defective, with Cbβ\DT-A^I.Scer\UAS (Fishilevich et al., 2005) smell perception defective, with Or42a^Scer\UAS.cFa (Gomez-Marin et al., 2011)
Phenotype Manifest In
	adult antennal lobe projection neuron VA1d adPN, with Cbβ\DT-A^I.Scer\UAS (Sweeney et al., 2011) adult olfactory receptor neuron Or59b, with Plc21C^GD11359 (Kain et al., 2008) antenna, with Gprk2^Scer\UAS.cTa (Tanoue et al., 2008) embryonic/larval olfactory receptor neuron, with Cbβ\DT-A^I.Scer\UAS (Sweeney et al., 2011)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement Reference Crei\ChR2^Scer\UAS.cSa, Scer\GAL4^{Orco.2.642.T:Hsim\VP22} has phototaxis defective phenotype, suppressible by norpA³⁶ (Bellmann et al., 2010) Scer\GAL4^{Orco.2.642.T:Hsim\VP22}, rdgA^GD1518 has neurophysiology defective phenotype, suppressible by Gαq^{dsRNA.Scer\UAS.1f1}, Scer\GAL4^{Orco.2.642.T:Hsim\VP22} (Kain et al., 2008, Kain et al., 2008) Scer\GAL4^{Orco.2.642.T:Hsim\VP22}, Zzzz\PACα^{Scer\UAS.cSLa} has phototaxis defective phenotype, suppressible by norpA³⁶ (Bellmann et al., 2010)
Suppressor of
Statement Reference Gαq^{dsRNA.Scer\UAS.1f1}, Scer\GAL4^{Orco.2.642.T:Hsim\VP22} is a suppressor of neurophysiology defective phenotype of Scer\GAL4^{Orco.2.642.T:Hsim\VP22}, rdgA^GD1518 (Kain et al., 2008, Kain et al., 2008)
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Scer\GAL4^{Orco.2.642.T:Hsim\VP22}/cyc^{Scer\UAS.T:Hsap\MYC} rescues cyc⁰¹/cyc⁰¹ (Tanoue et al., 2004) Scer\GAL4^{Orco.2.642.T:Hsim\VP22}/Gαq^Scer\UAS.cRa rescues Gαq^221c (Kain et al., 2008) Scer\GAL4^{Orco.2.642.T:Hsim\VP22}/Gαq^Scer\UAS.cRa rescues Gαq¹³⁷⁰ (Kain et al., 2008) Scer\GAL4^{Orco.2.642.T:Hsim\VP22}/Orco^Scer\UAS.cLa rescues Orco¹ (Wang and Anderson, 2010) Scer\GAL4^{Orco.2.642.T:Hsim\VP22}/Orco^Scer\UAS.cLa rescues Orco² (Larsson et al., 2004) Scer\GAL4^{Orco.2.642.T:Hsim\VP22}/Orco^{Scer\UAS.T:Avic\GFP-EGFP} rescues Orco² (Libert et al., 2007)
Partially rescues	Scer\GAL4^{Orco.2.642.T:Hsim\VP22}/Orco^Scer\UAS.cLa partially rescues Orco¹ (Larsson et al., 2004)
Fails to rescue	Scer\GAL4^{Orco.2.642.T:Hsim\VP22}/cyc^{Scer\UAS.T:Hsap\MYC} fails to rescue cyc⁰¹/cyc⁰¹ (Fujii et al., 2007)
Comments
Stocks ( 1 )
Bloomington	26818 w^*; P{Orco-GAL4.W}11.17; TM2/TM6B, Tb¹
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Scer\GAL4^{Or83b.2.642.T:Hsim\VP22} Scer\GAL4^{Orco.2.642.T:Hsim\VP22}
Name Synonym
Secondary FlyBase IDs

References ( 32 )

Generate a list of	All references relating to this allele ( 32 )

List References by type	Research paper ( 29 ) Supplementary material ( 2 ) FlyBase analysis ( 1 )
Recent research papers ( 7 )
	Eddison et al., 2012, PLoS ONE 7(12): e51684 A genetic screen for olfactory habituation mutations in Drosophila: analysis of novel foraging alleles and an underlying neural circuit. [FBrf0220425] Masuyama et al., 2012, J. Neurogenet. 26(1): 89--102 Mapping neural circuits with activity-dependent nuclear import of a transcription factor. [FBrf0217864] Plavicki et al., 2012, Proc. Natl. Acad. Sci. U.S.A. 109(5): 1578--1583 Homeobox gene distal-less is required for neuronal differentiation and neurite outgrowth in the Drosophila olfactory system. [FBrf0217395] Chen et al., 2011, Proc. Natl. Acad. Sci. U.S.A. 108(45): 18482--18487 Tomosyn-dependent regulation of synaptic transmission is required for a late phase of associative odor memory. [FBrf0216684] Gomez-Marin et al., 2011, Nat. Commun. 2: 441 Active sampling and decision making in Drosophila chemotaxis. [FBrf0214803] Hartl et al., 2011, J. Neurosci. 31(44): 15660--15673 A New Prospero and microRNA-279 Pathway Restricts CO2 Receptor Neuron Formation. [FBrf0216631] Sweeney et al., 2011, Neuron 72(5): 734--747 Secreted Semaphorins from Degenerating Larval ORN Axons Direct Adult Projection Neuron Dendrite Targeting. [FBrf0216932] Show all research papers ...

Allele Scer\GAL4Orco.2.642.T:Hsim\VP22

Allele Scer\GAL4^{Orco.2.642.T:Hsim\VP22}