Allele Scer\GAL4²²¹

General Information
Symbol	Scer\GAL4²²¹	Species	S. cerevisiae
Name		FlyBase ID	FBal0144600
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen
Recent Updates
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Caused by insertion	P{GawB}221 (Grueber et al., 2003, Ye et al., 2004, Parrish et al., 2006, Sweeney et al., 2006, Sweeney et al., 2006, Li et al., 2004, Lu et al., 2009, Parrish et al., 2009, Kirilly et al., 2009, Xu et al., 2008, Dimitrova et al., 2008, Mattie et al., 2010, Jinushi-Nakao et al., 2007, Tao and Rolls, 2011)
Cytology
Phenotypic Data
Phenotypic Class
	neuroanatomy defective, with ct^Scer\UAS.cPa (Li et al., 2004, Jinushi-Nakao et al., 2007) neuroanatomy defective, with Hsap\UBE3A^Scer\UAS.cRa (Lu et al., 2009) neuroanatomy defective, with kn^Scer\UAS.cMa (Jinushi-Nakao et al., 2007) neuroanatomy defective, with Mical^Scer\UAS.fl (Kirilly et al., 2009) neuroanatomy defective, with mir-9a^Scer\UAS.cLa (Xu et al., 2008) neuroanatomy defective, with mir-124^Scer\UAS.cXa (Xu et al., 2008) neuroanatomy defective, with Rac1^Scer\UAS.cLa (Jinushi-Nakao et al., 2007) neuroanatomy defective, with shrb^{dsRNA.Scer\UAS} (Sweeney et al., 2006) neuroanatomy defective, with shrb^{Scer\UAS.T:Avic\GFP} (Sweeney et al., 2006) neuroanatomy defective, with Sox14^fl.Scer\UAS (Kirilly et al., 2009) neuroanatomy defective, with spas^Scer\UAS.cSa (Jinushi-Nakao et al., 2007) neuroanatomy defective, with Ube3a^GD450 (Lu et al., 2009) neuroanatomy defective, with Ube3a^Scer\UAS.cLa (Lu et al., 2009)
Phenotype Manifest In
	abdominal 1 dorsal multidendritic neuron ddaE, with mir-9a^Scer\UAS.cLa (Xu et al., 2008) abdominal 1 dorsal multidendritic neuron ddaE, with mir-124^Scer\UAS.cXa (Xu et al., 2008) abdominal 1 dorsal multidendritic neuron ddaF, with mir-9a^Scer\UAS.cLa (Xu et al., 2008) abdominal 1 dorsal multidendritic neuron ddaF, with mir-124^Scer\UAS.cXa (Xu et al., 2008) abdominal posterior ventral multidendritic neuron vdap, with ab^Scer\UAS.cBa (Li et al., 2004) abdominal posterior ventral multidendritic neuron vdap, with ct^Scer\UAS.cPa (Li et al., 2004) class I dendritic arborizing neuron, with kn^Scer\UAS.cMa (Jinushi-Nakao et al., 2007) class I dendritic arborizing neuron, with Rac1^Scer\UAS.cLa (Jinushi-Nakao et al., 2007) class I dendritic arborizing neuron, with spas^Scer\UAS.cSa (Jinushi-Nakao et al., 2007) dendrite, with ct^Scer\UAS.cPa (Jinushi-Nakao et al., 2007) dendrite, with kn^Scer\UAS.cMa (Jinushi-Nakao et al., 2007) dendrite, with Mical^Scer\UAS.fl (Kirilly et al., 2009) dendrite, with mir-9a^Scer\UAS.cLa (Xu et al., 2008) dendrite, with mir-124^Scer\UAS.cXa (Xu et al., 2008) dendrite, with Rac1^Scer\UAS.cLa (Jinushi-Nakao et al., 2007) dendrite, with Sox14^fl.Scer\UAS (Kirilly et al., 2009) dendritic arborizing neuron, with mir-9a^Scer\UAS.cLa (Xu et al., 2008) dendritic arborizing neuron, with mir-124^Scer\UAS.cXa (Xu et al., 2008) dorsal multidendritic neuron ddaC, with ct^Scer\UAS.cPa (Jinushi-Nakao et al., 2007) dorsal multidendritic neuron ddaC, with Mical^Scer\UAS.fl (Kirilly et al., 2009) dorsal multidendritic neuron ddaC, with Sox14^fl.Scer\UAS (Kirilly et al., 2009) dorsal multidendritic neuron ddaE, with ab^Scer\UAS.cBa (Li et al., 2004) dorsal multidendritic neuron ddaE, with Hsap\UBE3A^Scer\UAS.cRa (Lu et al., 2009) dorsal multidendritic neuron ddaE, with shrb^{Scer\UAS.T:Avic\GFP} (Sweeney et al., 2006) dorsal multidendritic neuron ddaE, with spas^Scer\UAS.cSa (Jinushi-Nakao et al., 2007) dorsal multidendritic neuron ddaE, with Ube3a^GD450 (Lu et al., 2009) dorsal multidendritic neuron ddaE, with Ube3a^Scer\UAS.cLa (Lu et al., 2009) dorsal multidendritic neuron ddaE & dendritic tree \| ectopic, with shrb^{dsRNA.Scer\UAS} (Sweeney et al., 2006) dorsal multidendritic neuron ddaF, with Hsap\UBE3A^Scer\UAS.cRa (Lu et al., 2009) dorsal multidendritic neuron ddaF, with Ube3a^GD450 (Lu et al., 2009) dorsal multidendritic neuron ddaF, with Ube3a^Scer\UAS.cLa (Lu et al., 2009) dorsal multidendritic neuron ddaF & dendritic tree \| ectopic, with shrb^{dsRNA.Scer\UAS} (Sweeney et al., 2006) multidendritic dendrite \| ectopic, with ct^Scer\UAS.cPa (Grueber et al., 2003)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement Reference Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ has neuroanatomy defective phenotype, enhanceable by ct^Scer\UAS.cPa, Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, ct^Scer\UAS.cPa has neuroanatomy defective phenotype, enhanceable by kn^Scer\UAS.cMa/Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, ct^Scer\UAS.cPa has neuroanatomy defective phenotype, enhanceable by Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, kn^Scer\UAS.cMa has neuroanatomy defective phenotype, enhanceable by ct^Scer\UAS.cPa/Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, kn^Scer\UAS.cMa has neuroanatomy defective phenotype, enhanceable by Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007)
Suppressed by
Statement Reference Scer\GAL4²²¹, kn^Scer\UAS.cMa has neuroanatomy defective phenotype, suppressible by spas^{dsRNA.Scer\UAS}/Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, Sox14^fl.Scer\UAS has neuroanatomy defective phenotype, suppressible by Mical¹⁵²⁵⁶ (Kirilly et al., 2009)
Enhancer of
Statement Reference ct^Scer\UAS.cPa, Scer\GAL4²²¹ is an enhancer of neuroanatomy defective phenotype of Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) ct^Scer\UAS.cPa/Scer\GAL4²²¹ is an enhancer of neuroanatomy defective phenotype of Scer\GAL4²²¹, kn^Scer\UAS.cMa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) kn^Scer\UAS.cMa/Scer\GAL4²²¹ is an enhancer of neuroanatomy defective phenotype of Scer\GAL4²²¹, ct^Scer\UAS.cPa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ is an enhancer of neuroanatomy defective phenotype of Scer\GAL4²²¹, ct^Scer\UAS.cPa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ is an enhancer of neuroanatomy defective phenotype of Scer\GAL4²²¹, kn^Scer\UAS.cMa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007)
Suppressor of
Statement Reference Sox14^fl.Scer\UAS/Scer\GAL4²²¹ is a suppressor \| partially of neuroanatomy defective phenotype of Mical¹⁵²⁵⁶ (Kirilly et al., 2009) spas^{dsRNA.Scer\UAS}/Scer\GAL4²²¹ is a suppressor of neuroanatomy defective phenotype of Scer\GAL4²²¹, kn^Scer\UAS.cMa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007)
Phenotype Manifest In
Enhanced by
Statement Reference Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ has class I dendritic arborizing neuron phenotype, enhanceable by ct^Scer\UAS.cPa, Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ has dendrite phenotype, enhanceable by ct^Scer\UAS.cPa, Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, ct^Scer\UAS.cPa has class I dendritic arborizing neuron phenotype, enhanceable by kn^Scer\UAS.cMa/Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, ct^Scer\UAS.cPa has class I dendritic arborizing neuron phenotype, enhanceable by Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, ct^Scer\UAS.cPa has dendrite phenotype, enhanceable by kn^Scer\UAS.cMa/Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, ct^Scer\UAS.cPa has dendrite phenotype, enhanceable by Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, kn^Scer\UAS.cMa has class I dendritic arborizing neuron phenotype, enhanceable by ct^Scer\UAS.cPa/Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, kn^Scer\UAS.cMa has class I dendritic arborizing neuron phenotype, enhanceable by Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, kn^Scer\UAS.cMa has dendrite phenotype, enhanceable by ct^Scer\UAS.cPa/Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, kn^Scer\UAS.cMa has dendrite phenotype, enhanceable by Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007)
Suppressed by
Statement Reference Scer\GAL4²²¹, ct^Scer\UAS.cPa has abdominal posterior ventral multidendritic neuron vdap phenotype, suppressible \| partially by ab^Scer\UAS.cBa/Scer\GAL4²²¹ (Li et al., 2004, Li et al., 2004) Scer\GAL4²²¹, kn^Scer\UAS.cMa has class I dendritic arborizing neuron phenotype, suppressible by spas^{dsRNA.Scer\UAS}/Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, kn^Scer\UAS.cMa has dendrite phenotype, suppressible by spas^{dsRNA.Scer\UAS}/Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Scer\GAL4²²¹, Sox14^fl.Scer\UAS has dendrite phenotype, suppressible by Mical¹⁵²⁵⁶ (Kirilly et al., 2009) Scer\GAL4²²¹, Sox14^fl.Scer\UAS has dorsal multidendritic neuron ddaC phenotype, suppressible by Mical¹⁵²⁵⁶ (Kirilly et al., 2009)
Enhancer of
Statement Reference ct^Scer\UAS.cPa, Scer\GAL4²²¹ is an enhancer of class I dendritic arborizing neuron phenotype of Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) ct^Scer\UAS.cPa, Scer\GAL4²²¹ is an enhancer of dendrite phenotype of Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) ct^Scer\UAS.cPa/Scer\GAL4²²¹ is an enhancer of class I dendritic arborizing neuron phenotype of Scer\GAL4²²¹, kn^Scer\UAS.cMa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) ct^Scer\UAS.cPa/Scer\GAL4²²¹ is an enhancer of dendrite phenotype of Scer\GAL4²²¹, kn^Scer\UAS.cMa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) kn^Scer\UAS.cMa/Scer\GAL4²²¹ is an enhancer of class I dendritic arborizing neuron phenotype of Scer\GAL4²²¹, ct^Scer\UAS.cPa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) kn^Scer\UAS.cMa/Scer\GAL4²²¹ is an enhancer of dendrite phenotype of Scer\GAL4²²¹, ct^Scer\UAS.cPa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ is an enhancer of class I dendritic arborizing neuron phenotype of Scer\GAL4²²¹, ct^Scer\UAS.cPa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ is an enhancer of class I dendritic arborizing neuron phenotype of Scer\GAL4²²¹, kn^Scer\UAS.cMa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ is an enhancer of dendrite phenotype of Scer\GAL4²²¹, ct^Scer\UAS.cPa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) Rac1^Scer\UAS.cLa, Scer\GAL4²²¹ is an enhancer of dendrite phenotype of Scer\GAL4²²¹, kn^Scer\UAS.cMa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007)
Suppressor of
Statement Reference ab^Scer\UAS.cBa/Scer\GAL4²²¹ is a suppressor \| partially of abdominal posterior ventral multidendritic neuron vdap phenotype of Scer\GAL4²²¹, ct^Scer\UAS.cPa (Li et al., 2004, Li et al., 2004) Sox14^fl.Scer\UAS/Scer\GAL4²²¹ is a suppressor \| partially of dendrite phenotype of Mical¹⁵²⁵⁶ (Kirilly et al., 2009) Sox14^fl.Scer\UAS/Scer\GAL4²²¹ is a suppressor \| partially of dorsal multidendritic neuron ddaC phenotype of Mical¹⁵²⁵⁶ (Kirilly et al., 2009) spas^{dsRNA.Scer\UAS}/Scer\GAL4²²¹ is a suppressor of class I dendritic arborizing neuron phenotype of Scer\GAL4²²¹, kn^Scer\UAS.cMa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007) spas^{dsRNA.Scer\UAS}/Scer\GAL4²²¹ is a suppressor of dendrite phenotype of Scer\GAL4²²¹, kn^Scer\UAS.cMa (Jinushi-Nakao et al., 2007, Jinushi-Nakao et al., 2007)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	ab^Scer\UAS.cBa/Scer\GAL4²²¹ rescues ab¹/ab²⁶ (Li et al., 2004) ab^Scer\UAS.cBa/Scer\GAL4²²¹ rescues ab²⁶/[+] (Li et al., 2004) Dscam^{4.3-6.36-9.25-17.1}/Scer\GAL4²²¹ rescues Dscam²¹/Dscam²³ (Matthews et al., 2007) ss^Scer\UAS.A5/Scer\GAL4²²¹ rescues ss^D115.7/ss¹³⁴ (Kim et al., 2006) tutl^Scer\UAS.cLa/Scer\GAL4²²¹ rescues tutl⁰¹⁰⁸⁵/tutl²³ (Long et al., 2009) tutl^{Δcyto.Scer\UAS}/Scer\GAL4²²¹ rescues tutl⁰¹⁰⁸⁵/tutl²³ (Long et al., 2009)
Partially rescues	Dscam^{1.30.30.1.Scer\UAS}/Scer\GAL4²²¹ partially rescues Dscam²¹/Dscam²³ (Matthews et al., 2007) Dscam^{1.30.30.2.cMa.Scer\UAS}/Scer\GAL4²²¹ partially rescues Dscam²¹/Dscam²³ (Matthews et al., 2007)
Fails to rescue	Dscam^{4.3-6.36-9.25-17.2}/Scer\GAL4²²¹ fails to rescue Dscam²¹/Dscam²³ (Matthews et al., 2007)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer	D. Cox

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	GAL4^2-21 (Ye et al., 2004) Gal4^2-21 (Tsubouchi et al., 2009) Gal4²²¹ (Li et al., 2006, Parrish et al., 2006, Kim et al., 2006, Li et al., 2004, Matthews et al., 2007) GAL4²²¹ (Grueber et al., 2003, Nicolaï et al., 2010, Long et al., 2009) Gal-4²²¹ (Parrish et al., 2007) Scer\GAL4^2-21 Scer\GAL4²²¹
Name Synonym
Secondary FlyBase IDs
	FBal0155904
References ( 22 )

Generate a list of	All references relating to this allele ( 22 )

List References by type	Research paper ( 20 ) Supplementary material ( 2 )
Recent research papers ( 3 )
	Tao and Rolls, 2011, J. Neurosci. 31(14): 5398--5405 Dendrites have a rapid program of injury-induced degeneration that is molecularly distinct from developmental pruning. [FBrf0213404] Mattie et al., 2010, Curr. Biol. 20(24): 2169--2177 Directed Microtubule Growth, +TIPs, and Kinesin-2 Are Required for Uniform Microtubule Polarity in Dendrites. [FBrf0212550] Nicolaï et al., 2010, Proc. Natl. Acad. Sci. U.S.A. 107(47): 20553--20558 Genetically encoded dendritic marker sheds light on neuronal connectivity in Drosophila. [FBrf0212380] Show all research papers ...

Allele Scer\GAL4221

Allele Scer\GAL4²²¹