Allele Dmel\Bsb²

General Information
Symbol	Dmel\Bsb²	Species	D. melanogaster
Name		FlyBase ID	FBal0145168
Feature type	allele	Associated gene	Dmel\Bsb

Allele class
Mutagen
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	visible \| dominant (He and Adler, 2002)
Phenotype Manifest In
	actin filament & arista (He and Adler, 2002) arista (He and Adler, 2002) arista lateral (He and Adler, 2002) microtubule & arista (He and Adler, 2002)
Detailed Description
	Statement Reference Heterozygous flies have very short and highly branched arista laterals. The decreased length of the laterals is associated with a decreased rate of elongation and premature cessation of elongation. There is no delay in lateral outgrowth. Initially a single lateral is formed, but it is thicker than normal and sometimes individual bundles of actin filaments can be seen. The laterals split near the distal tip as they elongate and at later stages they appear to be split over more of their length. The shape of the laterals in cross section is often irregular, in contrast to the circular wild-type laterals. The actin bundles are irregular in shape and extend further into the centre of the lateral than normal, although most are still associated with the plasma membrane. The actin filaments occupy more of the lateral cross section than normal, although they appear less tightly packed than wild type. The density of microtubules is significantly reduced and their distribution is more irregular compared to wild type. (He and Adler, 2002)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Other
Statement Reference Bsb², Sb[+]/Sb¹ has visible \| dominant phenotype (Fei et al., 2002)
Phenotype Manifest In
Other
Statement Reference Bsb², Sb[+]/Sb¹ has ocellar bristle phenotype (Fei et al., 2002)
Additional Comments
Genetic Interactions
Statement Reference Sb¹ Bsb² double heterozygotes have ocellar bristles which are shorter and have a smaller volume than normal. (Fei et al., 2002)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Bsb² (Fei et al., 2002)
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Fei et al., 2002, J. Cell Sci. 115(19): 3797--3806 The growth of Drosophila bristles and laterals is not restricted to the tip or base. [FBrf0152120] He and Adler, 2002, Dev. Genes Evol. 212(5): 218--229 The genetic control of arista lateral morphogenesis in Drosophila. [FBrf0148956]

Allele Dmel\Bsb2

Allele Dmel\Bsb²