clathrin-coated vesicle & oocyte | germ-line clone
coated pit & oocyte | germ-line clone
cytoplasmic vesicle & oocyte | germ-line clone
nurse cell & plasma membrane | germ-line clone
Sec5E13/RopG27 transheterozygous third instar larvae show decreased number of terminal dendritic branches in the class IV dendritic arborizing neurons compared to either Sec5E13/+ or RopG27/+ single heterozygotes.
The cuticle defects seen at 25[o]C in embryos derived from exo84onr/Df(3R)Espl3 females mated to exo84onr heterozygous males are enhanced by sec5E13 (both parents are heterozygous for the second mutation).
Expression of sec8Scer\UAS.P\T.T:Ivir\HA1 under the control of Scer\GAL4nos.PG in homozygous female sec5E13 germline clones results in egg chamber development arresting between stages 7 and 9, such that these females lay no eggs. The oocyte nucleus migrates appropriately to the anterior end of the cell in the double mutant germlines at stage 7, but the oocyte fails to enlarge, remaining comparable in size to the nurse cells. Some disruption of the nurse cell membranes is seen, with some cells fused and the ring canals clustered together.