Allele Dmel\nkd^{EFX.Scer\UAS.T:Avic\GFP-EGFP}

General Information
Symbol	Dmel\nkd^{EFX.Scer\UAS.T:Avic\GFP-EGFP}	Species	D. melanogaster
Name		FlyBase ID	FBal0146979
Feature type	allele	Associated gene	Dmel\nkd

Allele class
Mutagen	in vitro construct - regulatory fusion, in vitro construct - coding region fusion
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - coding region fusion (Rousset et al., 2002) in vitro construct - regulatory fusion (Rousset et al., 2002)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of nkd which lacks amino acid residues 1-176 and 249-928 and is tagged at the C-terminal end with T:Avic\GFP^EGFP. (Waldrop et al., 2006) Construct: Scer\UAS regulatory sequences drive expression of amino acids 177 to 253 of nkd, tagged with T:Avic\GFP at the C-terminal end. (Rousset et al., 2002)
Carried in construct	P{UAS-nkd.EFX.GFPC} (Rousset et al., 2002, Waldrop et al., 2006)
Tagged with	T:Avic\GFP (Rousset et al., 2002) T:Avic\GFP^EGFP (Waldrop et al., 2006)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference Expression of nkd^R1S.Scer\UAS under the control of Scer\GAL4^B119 or Scer\GAL4^A8 does not result in any adult phenotypes. (Rousset et al., 2002)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to rescue	nkd^{EFX.Scer\UAS.T:Avic\GFP-EGFP}/Scer\GAL4^da.G32 fails to rescue nkd³/nkd² (Rousset et al., 2002)
Comments	Does not rescue the cuticle defects of nkd²/nkd³ embryos when expressed under the control of Scer\GAL4^da.G32. (Rousset et al., 2002)
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Nkd^EFX/GFPC (Waldrop et al., 2006) nkd^{EFX.Scer\UAS.T:Avic\GFP} nkd^{EFX.Scer\UAS.T:Avic\GFP-EGFP}
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Waldrop et al., 2006, Genetics 174(1): 331--348 An unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist naked cuticle. [FBrf0192436] Rousset et al., 2002, J. Biol. Chem. 277(50): 49019--49026 Zinc-dependent interaction between dishevelled and the Drosophila Wnt antagonist naked cuticle. [FBrf0155851]

Allele Dmel\nkdEFX.Scer\UAS.T:Avic\GFP-EGFP

Allele Dmel\nkd^{EFX.Scer\UAS.T:Avic\GFP-EGFP}