FlyBase Allele Report: Dmel\frc[NP0297]

General Information

Symbol

Dmel\frc^NP0297

Species

D. melanogaster

Name

FlyBase ID

FBal0147133

Feature type

allele

Associated gene

Dmel\frc

Associated Insertion(s)

P{GawB}frc^NP0297

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Goto et al., 2001)

Progenitor genotype

Associated Insertion(s)

P{GawB}frc^NP0297

Cytology

Description

P{GawB} insertion in the frc transcription unit.

(Goto et al., 2001)

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:17,433,166..17,433,360

(Olson et al., 2019, Goto et al., 2001)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with frc^R9)

(Goto et al., 2001)

visible

(Goto et al., 2001)

Phenotype Manifest In

anterior postalar bristle

(Goto et al., 2001)

anterior scutellar bristle

(Goto et al., 2001)

eye

(Goto et al., 2001)

macrochaeta

(Goto et al., 2001)

ommatidium

(Goto et al., 2001)

posterior postalar bristle

(Goto et al., 2001)

wing vein

(Goto et al., 2001)

Detailed Description

Statement

Reference

Mutants have rough and reduced eyes, severely nicked wing margins and thickened wing veins. Notal macrochaetae are often duplicated, with the anterior scutellar macrochaetae being the most often affected.

(Goto et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Other

Statement

Reference

Delta^9P, frc^NP0297 has anterior scutellar bristle phenotype

(Goto et al., 2001)

N^55e11, frc^NP0297 has anterior scutellar bristle phenotype

(Goto et al., 2001)

Ser^RX82, frc^NP0297 has anterior scutellar bristle phenotype

(Goto et al., 2001)

fng¹³, frc^NP0297 has anterior scutellar bristle phenotype

(Goto et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

frc^NP0297 in double heterozygous combination with N^55e11, Dl^9P, Ser^RX82 or fng¹³ results in duplications of the anterior scutellar bristles.

(Goto et al., 2001)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

frc^R9/frc^NP0297 is rescued by Scer\GAL4^NP0297/frc^UAS.Tag:MYC

(Goto et al., 2001)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Kyoto

103581

w^*; P{GawB}frc^NP0297 / TM3, Ser¹

Notes on Origin

Discoverer

Comments

Excision of the P{GawB} element reverts the mutant phenotype.

(Goto et al., 2001)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

frc^NP0297

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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