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General Information
Symbol
Dmel\mir-banD.UAS.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0147278
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-banD
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
Consists of a 100nt fragment that includes the hairpin region of the ban gene that has been cloned into the 3' UTR of Avic\GFPEGFP.UAS.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
The expression of banD.UAS.EGFP under the triple control of Scer\GAL4VP16.nos.UTR, Scer\GAL4nos.PG and Scer\GAL4VP16.otu leads to a significant increase in germline stem cells per germarium, as compared to controls.
Expression of banD.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4insc-Mz1407 in larval brains leads to an increase in the size of secondary neuroblasts and an increase in the nucleolar size in secondary neuroblasts, but no obvious change in the size of type II neuroblasts or type II neuroblast nucleoli, as compared to controls.
Expression of banD.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4C855a results in overproliferation of the optic lobe neuroepithelia in larvae.
When banD.Scer\UAS.T:Avic\GFP-EGFP is driven by Scer\GAL4en-e16E overgrowth is seen in the posterior compartment of the wing and of segments in the larval body.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Enhancer of
NOT Enhancer of
Suppressor of
NOT Suppressor of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Co-expression of MycKK103869 suppresses the increased nucleolar size seen in secondary neuroblasts in larval brains expressing banD.Scer\UAS.T:Avic\GFP-EGFP under the control of Scer\GAL4insc-Mz1407. Co-expression of banD.Scer\UAS.T:Avic\GFP-EGFP leads to enhancement of the ectopic neuroblast formation and increased neuroblast number phenotypes seen in larval brains expressing NScer\UAS.T:SV5\V5,T:Zzzz\His6 under the control of Scer\GAL4insc-Mz1407. Co-expression of banD.Scer\UAS.T:Avic\GFP-EGFP fails to suppress the ectopic type II neuroblast phenotype seen in larval brain clones expressing numbTS4D.Scer\UAS under the control of Scer\GAL4Act.PU.
Xenogenetic Interactions
Statement
Reference
Expression of banD.Scer\UAS.T:Avic\GFP-EGFP, bearing only a 100bp region containing the ban miRNA suppresses degeneration in Hsap\MJDtr.Q78.Scer\UAS.T:Ivir\HA1 Scer\GAL4GMR.PF flies, restoring external and internal eye structures towards normal.
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
banD.Scer\UAS.T:Avic\GFP-EGFP
banD.UAS.EGFP
mir-banD.UAS.EGFP
Name Synonyms
Secondary FlyBase IDs
    References (9)