FB2025_01 , released February 20, 2025
Allele: Dmel\HDAC4KG09091
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General Information
Symbol
Dmel\HDAC4KG09091
Species
D. melanogaster
Name
FlyBase ID
FBal0147884
Feature type
allele
Associated gene
Dmel\HDAC4
Associated Insertion(s)
P{SUPor-P}HDAC4KG09091
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{SUPor-P}HDAC4KG09091
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{SUPor-P}
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  Alzheimer's disease
      modeled by Hsap\APPAβ42.GMR.Tag:SS(rPENK)
      (Cao et al., 2008)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      HDAC4KG09091/HDAC4[+] is an enhancer of eye phenotype of Hsap\APPAβ42.GMR.Tag:SS(rPENK)

      (Cao et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Lipid levels are completely restored in HDAC4KG09091/HDAC4e04575 ; Sik348double mutant flies.

      (Wang et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      HDAC4KG09091
      (Choi et al., 2015, Liu et al., 2014, Wang et al., 2011, Cao et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)