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General Information
Symbol
Dmel\CbydsRNA.UAS.WIZ
Species
D. melanogaster
Name
FlyBase ID
FBal0148115
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
dsRNA corresponding to +3 to +273bp of the Cby ORF is expressed under the control of UAS sequences.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
CbydsRNA.Scer\UAS.WIZ; Scer\GAL4nos.PG embryos form cuticles characterized by the transformation of ventral denticles into naked cuticle. In addition, these embryos are smaller than wild-type and are missing head structures.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
When CbydsRNA.Scer\UAS.WIZ is driven by Scer\GAL4arm.PS in a armF1α germ-line clone background, the ectopic denticle phenotype is suppressed. armF1α, armΔ.Scer\UAS.T:Ivir\HA1, CbydsRNA.Scer\UAS.WIZ (driven by Scer\GAL4arm.PS) germ-line clones exhibit a naked cuticle phenotype. When CbydsRNA.Scer\UAS.WIZ is driven by Scer\GAL4arm.PS in a armΔ.Scer\UAS.T:Ivir\HA1 germ-line clone background, the ectopic denticle phenotype is enhanced.
Expression of CbydsRNA.Scer\UAS.WIZ under the control of Scer\GAL4arm.PS has no effect on the cuticle phenotype of embryos derived from armF1α germ-line clones. Co-expression of CbydsRNA.Scer\UAS.WIZ in a armF1α, armΔ.Scer\UAS.T:Ivir\HA1, Scer\GAL4arm.PS background leads to increased naked cuticle compared to armF1α, armΔ.Scer\UAS.T:Ivir\HA1, Scer\GAL4arm.PS embryos.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments
dsRNA is expressed in transgenic flies to study the phenotypic consequences of dsRNA interference (RNAi) of the Cby gene.
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CbydsRNA.Scer\UAS.WIZ
CbydsRNA.UAS.WIZ
Name Synonyms
Secondary FlyBase IDs
    References (2)