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General Information
Symbol
Dmel\vls+tMa
Species
D. melanogaster
Name
FlyBase ID
FBal0148346
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Linked to:
EcoRI-HindIII restriction fragment
Comment:

Position of restriction fragment on reference sequence inferred by FlyBase curator; the 5' end is approximate.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Genomic fragment containing the complete vls gene and the 3' part of lok.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Embryos derived from lok null mothers (Df(2L)pr2b/Df(2L)be408 females carrying P{CG10728+tMa} to rescue vls function and P{barr+tMa} to rescue barr function) have an average of 24.5 pole cells/embryo compared to the wild-type number of 37.3 pole cells/embryo. The progeny of the lok null flies are viable and fertile, they show no increase in the rate of X chromosome nondisjunction compared to controls and females show no defects in meiotic recombination frequency. lok null larvae are not more sensitive to methyl methanesulfonate or hydroxyurea than control larvae. Irradiation does not result in a delay of entry into mitosis in lok null embryos, in contrast to wild-type embryos.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CG10728+tMa
vls+tMa
Name Synonyms
Secondary FlyBase IDs
    References (3)