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General Information
Symbol
Dmel\hhN.UAS.cGa
Species
D. melanogaster
Name
FlyBase ID
FBal0150433
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UASt regulatory sequences drive expression of a truncated hh open reading frame (a stop codon has been introduced at codon 258). This is expected to result in a protein in which addition of cholesterol to the C-terminal end of the protein does not occur, while palmitoylation can still occur at the N-terminal end.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
hhN.Scer\UAS.cGa expressing cells display strong punctate labeling on the plasma membrane. Clones of peripodial cells expressing hhN.Scer\UAS.cGa under the control of Scer\GAL4en-e16E induce significant outgrowth of the anterior compartment of the wing imaginal disc.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Clones of peripodial cells expressing both hhN.Scer\UAS.cGa and dispScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4en-e16E induce significant outgrowth of the anterior compartment of the wing imaginal disc.
Expression of hhN.Scer\UAS.cGa with Scer\GAL4en-e16E in dispS037707 germ-line clone embryos doesn't rescue naked cuticle formation, but does increase denticle diversity in the ventral cuticle: row 3,4 and 5 type denticles are all present: denticles type 3 and 4 cover each segment, whereas type 5 denticles have almost totally disappeared.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments
Expression of hhN.Scer\UAS.cGa, under the control of Scer\GAL4unspecified rescues the hhAC phenotype.
Naked cuticle formation in hhAC homozygous embryonic cuticle is partially rescued by hhN.Scer\UAS.T:Ivir\HA1; Scer\GAL469B (some denticle belts are fused at the midline). The denticle belts formed consist of (A-P) a single row 1 type followed by a number of row 2, sometimes followed by a row 1.
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
hhN.Scer\UAS.cGa
hhN.UAS.cGa
Name Synonyms
Secondary FlyBase IDs
    References (2)