Allele Dmel\gig^{S924A.Scer\UAS.T:Zzzz\FLAG}

General Information
Symbol	Dmel\gig^{S924A.Scer\UAS.T:Zzzz\FLAG}	Species	D. melanogaster
Name		FlyBase ID	FBal0150483
Feature type	allele	Associated gene	Dmel\gig

Allele class
Mutagen	in vitro construct - regulatory fusion, in vitro construct - coding region fusion
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	in vitro construct - coding region fusion (Potter et al., 2002) in vitro construct - regulatory fusion (Potter et al., 2002)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: Amino acid replacement: S924A. Expression of mutated gig, fused at the N-terminus to the epitope tag T:Zzzz\FLAG, is driven by Scer\UAS sequences. (Potter et al., 2002)
Carried in construct	P{UAS-gig.S924A.FLAG} (Potter et al., 2002)
Tagged with	T:Zzzz\FLAG (Potter et al., 2002)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement Reference gig^{S924A.Scer\UAS.T:Zzzz\FLAG}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF is a suppressor \| partially of ommatidium phenotype of Akt1^{Scer\UAS.T:Ivir\HA1}, Scer\GAL4^GMR.PF/Scer\GAL4^GMR.PF (Potter et al., 2002)
Other
Statement Reference Scer\GAL4^ey.PH, Tsc1^{Scer\UAS.T:Hsap\MYC}, gig^{S924A.Scer\UAS.T:Zzzz\FLAG} has eye phenotype (Potter et al., 2002, Potter et al., 2002) Scer\GAL4^ey.PH, Tsc1^{Scer\UAS.T:Hsap\MYC}, gig^{S924A.Scer\UAS.T:Zzzz\FLAG} has ommatidium phenotype (Potter et al., 2002, Potter et al., 2002)
Additional Comments
Genetic Interactions
Statement Reference gig^{S924A.Scer\UAS.T:Zzzz\FLAG}/Scer\GAL4^ey.PH; Tsc1^{Scer\UAS.T:Hsap\MYC}/+ flies have small eyes with an approximately 45% decrease in ommatidia numbers compared to wild-type. The increase in ommatidial size seen in Akt1^{Scer\UAS.T:Ivir\HA1}; Scer\GAL4^GMR.PF flies is partially suppressed by gig^{S924A.Scer\UAS.T:Zzzz\FLAG}. (Potter et al., 2002)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	gig^{S924A.Scer\UAS.T:Zzzz\FLAG}
Name Synonym
Secondary FlyBase IDs

References ( 1 )
Research paper	Potter et al., 2002, Nat. Cell Biol. 4(9): 658--665 Akt regulates growth by directly phosphorylating Tsc2. [FBrf0152244]

Allele Dmel\gigS924A.Scer\UAS.T:Zzzz\FLAG

Allele Dmel\gig^{S924A.Scer\UAS.T:Zzzz\FLAG}