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General Information
Symbol
Dmel\Mmp2G535R
Species
D. melanogaster
Name
FlyBase ID
FBal0150749
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G9612899A

Amino acid change:

G535R | Mmp2-PB; G383R | Mmp2-PC; G427R | Mmp2-PD

Reported amino acid change:

G535R

Comment:

Site of nucleic acid difference in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: G535R.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Randomly generated Mmp2G535R mutant clones rarely populate the tip-cell territory in the air sac primordium.

94% of Mmp2G535R/Mmp2Df animals survive to third instar, all of which pupariate, 47% undergo head eversion, 18% develop head bristles, but none eclose. 74% (n = 23) of Mmp2G535R/Mmp2Df pupae have a melanized lump in the developing thorax, visible as a black spot through the pupal case. The black spot appears before head eversion, varies in size, and remains evident in animals with fully developed legs and bristles.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Mmp2G535R
Name Synonyms
Secondary FlyBase IDs
    References (2)