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General Information
Symbol
Dmel\Mmp2A218V
Species
D. melanogaster
Name
FlyBase ID
FBal0150752
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

C9614916T

Amino acid change:

A218V | Mmp2-PB; A66V | Mmp2-PC; A110V | Mmp2-PD

Reported amino acid change:

A218V

Comment:

Site of nucleic acid difference in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: A218V.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mmp2A218V mutant animals survive to 3rd instar, and 94% pupariate, but only 25% undergo head eversion, 8% develop head bristles and none eclose. Mutant late pupae/pharate adults often have a cleft bisecting the notum along the midline. Mmp2A218V/Mmp2Df animals survive to third instar, and 96% pupariate, but only 13% undergo head eversion, 6% develop head bristles and none eclose.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

A moderate delay in fat body cell dissociation during metamorphosis is seen in Mmp1Q273stop Mmp2A218V double heterozygotes.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (3)