Expression of vri^2.Scer\UAS under the control of Scer\GAL4^{Hand.ΔVM.Switch} (initiated by feeding flies RU486 during adulthood) results in a large decrease in heart rate by 10 days. This is dependent on the concentration of RU486. The heart period (mean time between successive end-diastolic positions) is higher in 45 day old flies than in age-matched controls, but frequency of arrhythmicity is unaffected. These flies also exhibit a moderate dilated heart phenotype; an increase in End-Diastolic Diameter (EDD) is seen between 10 and 45 days rather than the decrease seen in wild type.

Expression of one copy of vri^2.Scer\UAS under the control of Scer\GAL4^Bx-MS1096 results in an enlarged L3 wing vein, enlarged cell size (as shown by more widely spaced wing bristles) and multiple trichomes, some of which have abnormal morphology. Expression of two copies of vri^2.Scer\UAS under the control of Scer\GAL4^Bx-MS1096 results in wings that are greatly reduced in size and have cells with multiple trichomes of abnormal morphology.

Scer\GAL4^Bx-MS1096, vri^2.UAS has visible phenotype, non-suppressible by stg^UAS.cNa/Scer\GAL4^Bx-MS1096

Scer\GAL4^Bx-MS1096, vri^2.UAS has visible phenotype, non-suppressible by CycE^UAS.cLa, Scer\GAL4^Bx-MS1096