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General Information
Symbol
Dmel\rlSem.S.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0151605
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-rlSem
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of an activated form of rl.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expressing rlSem.S.UAS under the control of Scer\GAL4C587 does not induce any obvious L3 spermatogenesis defects.

Expression of rlSem.S.Scer\UAS under the control of Scer\GAL4salm.EPv leads to formation of extra vein material in adult wings.

Expression of rlSem.S.Scer\UAS under the control of Scer\GAL4da.G32 results in the formation of additional vein material, and a smaller overall sized wing is observed.

Expression of rlSem.S.Scer\UAS in the eye under the control of Scer\GAL4da.G32 results in mild irregularities in ommatidial pattern.

Flies expressing rlSem.S.Scer\UAS under the control of Scer\GAL4da.G32 have a survival rate of 42%.

Flies carrying rlSem.S.Scer\UAS have some additional wing veins, even in the absence of an Scer\GAL4 driver.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Suppressed by
Enhancer of
Statement
Reference
NOT Suppressor of
Phenotype Manifest In
Enhanced by
Suppressed by
NOT suppressed by
Statement
Reference
Enhancer of
NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The formation of ectopic wein material in the adult wing characteristic for flies expressing rlSem.S.Scer\UAS under the control of Scer\GAL4salm.EPv is partially suppressed by co-expression of either Usp47GD10642 or Usp47NIG.5486R. The ameliorated phenotype of Scer\GAL4salm.EPv,rlSem.S.Scer\UAS;Usp47GD10642 flies can be worsened again by co-expression of either poeGD8339 or poeKK101471 : the severity of their ectopic venation phenotype is comparable to that of flies expressing rlSem.S.Scer\UAS only.

Expression of rlSem.S.Scer\UAS under the control of Scer\GAL4da.G32 in a krzS047819/+ mutant background results in the development of even more additional veins in the wing and a further reduction in wing size.

Expression of rlSem.S.Scer\UAS and krzScer\UAS.T:Zzzz\GS-TAP under the control of Scer\GAL4da.G32 in a krzS047819/+ mutant background restores the wing vein phenotype to that seen in animals expressing just rlSem.S.Scer\UAS under the control of Scer\GAL4da.G32 in a wild-type background. Wing size is larger in these flies compared to animals expressing rlSem.S.Scer\UAS under the control of Scer\GAL4da.G32 in a wild-type background.

The mild irregularities in ommatidial pattern observed in animals expressing rlSem.S.Scer\UAS under the control of Scer\GAL4da.G32 is strongly enhanced in a krzS047819/+ mutant background, and smaller rougher eyes are observed.

Expression of krzScer\UAS.T:Zzzz\GS-TAP restores the regular ommatidial pattern and size of the eye in animals expressing rlSem.S.Scer\UAS under the control of Scer\GAL4da.G32 in a krzS047819/+ mutant background.

The survival rate of animals expressing rlSem.S.Scer\UAS under the control of Scer\GAL4da.G32 drops to 8% in a krzS047819/+ mutant background.

The survival rate of animals expressing rlSem.S.Scer\UAS under the control of Scer\GAL4da.G32 in a krzS047819/+ mutant background increases to 38% when krzScer\UAS.T:Zzzz\GS-TAP is co-expressed.

Co-expression of rlSem.S.Scer\UAS enhances the mutant wing phenotype caused by expression of MadScer\UAS.cNa under the control of Scer\GAL4vg.int2.1.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
rlSem.S.Scer\UAS
rlSem.S.UAS
Name Synonyms
Secondary FlyBase IDs
    References (7)