FB2025_01 , released February 20, 2025
Allele: Dmel\ovosvb.UAS
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General Information
Symbol
Dmel\ovosvb.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0151650
Feature type
allele
Associated gene
Dmel\ovo
Associated Insertion(s)
Carried in Construct
P{UAS-ovo.svb}
Also Known As
UAS-svb
Key Links
Transgenic product class
cDNA
(Delon et al., 2003)
wild_type
(Delon et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Delon et al., 2003)
wild_type
(Delon et al., 2003)
Mutagen
in vitro construct
(Delon et al., 2003)
Progenitor genotype
Carried in construct
P{UAS-ovo.svb}
Cytology
Description

UAS regulatory sequences drive expression of the ovo EST LD47350 (which encodes the "svb" isoform).

(Delon et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
ovo
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of ovosvb.Scer\UAS under the control of Scer\GAL4e22c produces small ectopic denticles in the naked cuticle regions and also disrupts the normal arrangement and morphology of denticles within denticle belts.

      (Bejsovec and Chao, 2012)

      Expression of ovosvb.Scer\UAS under the control of Scer\GAL4bab1-GAL4-U does not produce a mutant phenotype in the leg.

      (Pueyo and Couso, 2011)

      Expression of ovosvb.Scer\UAS in embryos, under the control of Scer\GAL4wg.PM, results in the formation of supernumerary denticles.

      Expression of ovosvb.Scer\UAS, under the control of Scer\GAL4ptc-559.1, show ectopic cuticular extensions on the embryonic epidermis; these ectopic extensions are as densely pigmented as wild-type denticles.

      (Chanut-Delalande et al., 2006)

      Expression of ovosvb.Scer\UAS under the control of Scer\GAL4ptc-559.1 induces the formation of ectopic denticles in cells that normally form smooth cuticle. Expression of ovosvb.Scer\UAS under the control of Scer\GAL4Bx-MS1096 increases adult wing hair length and density. F-actin pupal prehairs in the wing are longer than normal in these animals and supernumerary prehairs are formed. The ectopic prehairs retain a normal distal-most location and orientation in the cell. Expression of ovosvb.Scer\UAS under the control of Scer\GAL4GMR.PF impairs bristle formation in the eye and results in the formation of ectopic extensions on the ommatidia.

      (Delon et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of ovosvb.Scer\UAS under the control of Scer\GAL4e22c in a ckKT9 background causes a strong reduction in denticle size and results in a change in denticle morphology, while the ectopic denticles found between the denticle belts in animals expressing ovosvb.Scer\UAS under the control of Scer\GAL4e22c in a wild-type background are virtually eliminated.

      (Bejsovec and Chao, 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4ptc-559.1/ovosvb.UAS rescues ovounspecified

      (Delon et al., 2003)
      Comments

      Expression of ovosvb.Scer\UAS under the control of Scer\GAL4ptc-559.1 rescues the formation of denticles in "svb" mutants of ovo.

      (Delon et al., 2003)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ovosvb.Scer\UAS
      ovosvb.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (6)