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General Information
Symbol
Dmel\nrv2unspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0151676
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    nrv2unspecified mutant embryos display decreased muscle contractions, a failure to properly inflate their trachea, and abnormal salivary gland morphology.

    Septate junction components are mislocalized or dramatically reduced in nrv2unspecified mutant embryos in their trachea, epidermis and salivary glands.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Other
    Statement
    Reference

    cora1/cora2, nrv2[+]/nrv2unspecified has embryonic salivary gland & epithelial cell phenotype

    cora1/cora2, nrv2unspecified has embryonic salivary gland & epithelial cell phenotype

    cora2, nrv2unspecified has embryonic salivary gland & epithelial cell phenotype

    cora2, nrv2[+]/nrv2unspecified has embryonic salivary gland & epithelial cell phenotype

    Additional Comments
    Genetic Interactions
    Statement
    Reference

    cora1/cora2 or cora2/cora2 mutant embryos have an effective diffusion barrier in the embryonic salivary glands that is disrupted when nrv2unspecified/+ is present.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    nrv2unspecified
    Name Synonyms
    Secondary FlyBase IDs
      References (3)