lsn5F3-8 somatic clones in eye-antennal imaginal discs contain enlarged, abnormal early endosomes.
lsn5F3-8 somatic clones in eye-antennal imaginal discs show high levels of apoptosis compared to wildtype. However, non-autonomous overgrowth of the eye-antennal imaginal disc, adult eye and head occurs these animals.
When the majority of cells in the eye-antennal imaginal discs are mutant for lsn5F3-8, striking tissue overgrowth of the disc occurs and loose cellular architecture is observed.
lsn5F3-8 mutant somatic clones in eye-antennal imaginal discs do not proliferate very well, however the wildtype tissue immediately adjacent to the mutant clones show increased cell proliferation rates.
Females with homozygous germline clones do not lay eggs.