FB2019_05, released Oct 15, 2019

Allele: Dmel\ktoUAS.cJa

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General Information
Symbol
Dmel\ktoUAS.cJa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Janody
FlyBase ID
FBal0151811
Feature type
allele
Associated gene
Dmel\kto
Associated Insertion(s)
Carried in Construct
P{UAS-kto.J}
Also Known As
UAS-kto
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Janody et al., 2003)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{UAS-kto.J}
      Cytology
      Nature of the lesion
      Statement
      Reference
      UASt regulatory sequences drive expression of a full length kto cDNA.
      (Janody et al., 2003)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      UASt
      Encoded product / tool
      kto
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      Expression via Scer\GAL4wor.PA and Scer\GAL80ase.PN prolongs the lifetime and prevents shrinkage of pupal neuroblasts (NBs) without having any obvious effects on larval NBs.
      (Homem et al., 2014)
      Expression of ktoScer\UAS.cJa under the control of Scer\GAL4vg.PM results in a reduction of the wing margin. Clones in the wing disc expressing ktoScer\UAS.cJa under the control of Scer\GAL4αTub84B.PL distort the dorsal-ventral compartment boundary.
      (Janody et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference
      Scer\GAL4vg.PM, ktoUAS.cJa has visible phenotype, enhanceable by skdUAS.cJa/Scer\GAL4vg.PM
      (Janody et al., 2003)
      Enhancer of
      Statement
      Reference
      ktoUAS.cJa/Scer\GAL4vg.PM is an enhancer of visible phenotype of Scer\GAL4vg.PM, skdUAS.cJa
      (Janody et al., 2003)
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference
      Scer\GAL4vg.PM, ktoUAS.cJa has wing margin phenotype, enhanceable by skdUAS.cJa/Scer\GAL4vg.PM
      (Janody et al., 2003)
      Enhancer of
      Statement
      Reference
      ktoUAS.cJa/Scer\GAL4vg.PM is an enhancer of wing margin phenotype of Scer\GAL4vg.PM, skdUAS.cJa
      (Janody et al., 2003)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Co-expression of both ktoScer\UAS.cJa and skdScer\UAS.cJa under the control of Scer\GAL4vg.PM results in a stronger reduction of the wing margin than is seen when either ktoScer\UAS.cJa or skdScer\UAS.cJa is expressed alone. Clones in the wing disc co-expressing ktoScer\UAS.cJa and skdScer\UAS.cJa under the control of Scer\GAL4αTub84B.PL are smaller in size than clones expressing either ktoScer\UAS.cJa or skdScer\UAS.cJa alone.
      (Janody et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues
      ktoUAS.cJa/Scer\GAL4da.G32 partially rescues ktoT555/ktoT241
      (Janody et al., 2003)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ktoScer\UAS.cJa
      ktoUAS.cJa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Janody
      (Janody et al., 2003)
      Secondary FlyBase IDs
        References (3)