Co-expression of yki^{S111A.Scer\UAS.T:SV5\V5} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with very small eyes. Co-expression of yki^{S250A.Scer\UAS.T:SV5\V5} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with small eyes. Co-expression of yki^{S111A.S250A.Scer\UAS.T:SV5\V5} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with small eyes. Co-expression of yki^{S111A.S250A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with very small eyes. Co-expression of yki^{S168A.Scer\UAS.T:SV5\V5} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with greatly enlarged eyes. Co-expression of yki^{S168A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with enlarged eyes. Co-expression of yki^{S111A.S168A.Scer\UAS.T:SV5\V5} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with greatly enlarged eyes (but less so than in the absence of hpo^{Scer\UAS.T:Zzzz\FLAG}). Co-expression of yki^{S111A.S168A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with greatly enlarged eyes (but less so than in the absence of wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG}). Co-expression of yki^{S168A.S250A.Scer\UAS.T:SV5\V5} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with greatly enlarged eyes (but less so than in the absence of hpo^{Scer\UAS.T:Zzzz\FLAG}). Co-expression of yki^{S168A.S250A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with greatly enlarged eyes (but less so than in the absence of wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG}). Co-expression of yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with enlarged and highly folded eyes. Co-expression of yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with enlarged and highly folded eyes. Clones in the wing disc co-expressing yki^{S111A.S250A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^Act5C.PI do not survive well. Large round clones are still observed in the wing disc when yki^{S168A.Scer\UAS.T:SV5\V5} is co-expressed with wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^Act5C.PI in the clones. Co-expression of ex^Scer\UAS.cBa in clones expressing yki^{S168A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^Act5C.PI decreases the size and number of clones recovered in the wing disc. Clones co-expressing yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5} ex^Scer\UAS.cBa, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^Act5C.PI in the wing disc are large and round.

(Oh and Irvine, 2009)

Clones of cells in the wing or eye disc in which wts^{Scer\UAS.T:Hsap\MYC}, hpo^{Scer\UAS.T:Zzzz\FLAG} and ex^Scer\UAS.cBa are over-expressed together with yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5} generally overgrow compared to control clones, but can be less overgrown than yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5}-expressing clones alone. This is most evident in the wing pouch. The overgrowth and folding of the eye disc induced by Scer\GAL4^GMR.PU-mediated expression of yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5} is largely suppressed by co-expression of wts^{Scer\UAS.T:Hsap\MYC}, hpo^{Scer\UAS.T:Zzzz\FLAG} and ex^Scer\UAS.cBa. The overgrowth and folding of the eye disc induced by Scer\GAL4^GMR.PU-mediated expression of yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5} is not suppressed by co-expression of hpo^{Scer\UAS.T:Zzzz\FLAG} alone. The overgrowth and folding of the eye disc induced by Scer\GAL4^GMR.PU-mediated expression of yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5} is partly suppressed by co-expression of wts^{Scer\UAS.T:Hsap\MYC}, hpo^{Scer\UAS.T:Zzzz\FLAG} together, or hpo^{Scer\UAS.T:Zzzz\FLAG} and ex^Scer\UAS.cBa together.

(Oh et al., 2009)

Clones co-expressing hpo^{Scer\UAS.T:Zzzz\FLAG} and yki^{Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^Act5C.PI in the wing disc are tiny and rarely detected. Clones co-expressing hpo^{Scer\UAS.T:Zzzz\FLAG} and yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} under the control of Scer\GAL4^Act5C.PI are recovered in the wing disc. Clones co-expressing hpo^{Scer\UAS.T:Zzzz\FLAG} and wts^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Act5C.PI are not recovered in the wing disc. Clones co-expressing hpo^{Scer\UAS.T:Zzzz\FLAG}, yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} and wts^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Act5C.PI are not recovered in the wing disc.

(Oh and Irvine, 2008)