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General Information
Symbol
Dmel\hpoUAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0151842
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-hpo
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UASt sequences drive expression of hpo tagged with Tag:FLAG.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Clones expressing hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4Act5C.PI are not recovered in the wing disc.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
NOT Suppressor of
Other
Statement
Reference
Phenotype Manifest In
Suppressed by
NOT suppressed by
Suppressor of
NOT Suppressor of
Other
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Co-expression of ykiS111A.Scer\UAS.T:SV5\V5 and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with very small eyes. Co-expression of ykiS250A.Scer\UAS.T:SV5\V5 and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with small eyes. Co-expression of ykiS111A.S250A.Scer\UAS.T:SV5\V5 and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with small eyes. Co-expression of ykiS111A.S250A.Scer\UAS.T:SV5\V5, wtsScer\UAS.T:Hsap\MYC and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with very small eyes. Co-expression of ykiS168A.Scer\UAS.T:SV5\V5 and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with greatly enlarged eyes. Co-expression of ykiS168A.Scer\UAS.T:SV5\V5, wtsScer\UAS.T:Hsap\MYC and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with enlarged eyes. Co-expression of ykiS111A.S168A.Scer\UAS.T:SV5\V5 and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with greatly enlarged eyes (but less so than in the absence of hpoScer\UAS.T:Zzzz\FLAG). Co-expression of ykiS111A.S168A.Scer\UAS.T:SV5\V5, wtsScer\UAS.T:Hsap\MYC and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with greatly enlarged eyes (but less so than in the absence of wtsScer\UAS.T:Hsap\MYC and hpoScer\UAS.T:Zzzz\FLAG). Co-expression of ykiS168A.S250A.Scer\UAS.T:SV5\V5 and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with greatly enlarged eyes (but less so than in the absence of hpoScer\UAS.T:Zzzz\FLAG). Co-expression of ykiS168A.S250A.Scer\UAS.T:SV5\V5, wtsScer\UAS.T:Hsap\MYC and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with greatly enlarged eyes (but less so than in the absence of wtsScer\UAS.T:Hsap\MYC and hpoScer\UAS.T:Zzzz\FLAG). Co-expression of ykiS111A.S168A.S250A.Scer\UAS.T:SV5\V5 and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with enlarged and highly folded eyes. Co-expression of ykiS111A.S168A.S250A.Scer\UAS.T:SV5\V5, wtsScer\UAS.T:Hsap\MYC and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4GMR.PF results in flies with enlarged and highly folded eyes. Clones in the wing disc co-expressing ykiS111A.S250A.Scer\UAS.T:SV5\V5, wtsScer\UAS.T:Hsap\MYC and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4Act5C.PI do not survive well. Large round clones are still observed in the wing disc when ykiS168A.Scer\UAS.T:SV5\V5 is co-expressed with wtsScer\UAS.T:Hsap\MYC and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4Act5C.PI in the clones. Co-expression of exScer\UAS.cBa in clones expressing ykiS168A.Scer\UAS.T:SV5\V5, wtsScer\UAS.T:Hsap\MYC and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4Act5C.PI decreases the size and number of clones recovered in the wing disc. Clones co-expressing ykiS111A.S168A.S250A.Scer\UAS.T:SV5\V5 exScer\UAS.cBa, wtsScer\UAS.T:Hsap\MYC and hpoScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4Act5C.PI in the wing disc are large and round.
Clones of cells in the wing or eye disc in which wtsScer\UAS.T:Hsap\MYC, hpoScer\UAS.T:Zzzz\FLAG and exScer\UAS.cBa are over-expressed together with ykiS111A.S168A.S250A.Scer\UAS.T:SV5\V5 generally overgrow compared to control clones, but can be less overgrown than ykiS111A.S168A.S250A.Scer\UAS.T:SV5\V5-expressing clones alone. This is most evident in the wing pouch. The overgrowth and folding of the eye disc induced by Scer\GAL4GMR.PU-mediated expression of ykiS111A.S168A.S250A.Scer\UAS.T:SV5\V5 is largely suppressed by co-expression of wtsScer\UAS.T:Hsap\MYC, hpoScer\UAS.T:Zzzz\FLAG and exScer\UAS.cBa. The overgrowth and folding of the eye disc induced by Scer\GAL4GMR.PU-mediated expression of ykiS111A.S168A.S250A.Scer\UAS.T:SV5\V5 is not suppressed by co-expression of hpoScer\UAS.T:Zzzz\FLAG alone. The overgrowth and folding of the eye disc induced by Scer\GAL4GMR.PU-mediated expression of ykiS111A.S168A.S250A.Scer\UAS.T:SV5\V5 is partly suppressed by co-expression of wtsScer\UAS.T:Hsap\MYC, hpoScer\UAS.T:Zzzz\FLAG together, or hpoScer\UAS.T:Zzzz\FLAG and exScer\UAS.cBa together.
Clones co-expressing hpoScer\UAS.T:Zzzz\FLAG and ykiScer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1 under the control of Scer\GAL4Act5C.PI in the wing disc are tiny and rarely detected. Clones co-expressing hpoScer\UAS.T:Zzzz\FLAG and ykiS168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1 under the control of Scer\GAL4Act5C.PI are recovered in the wing disc. Clones co-expressing hpoScer\UAS.T:Zzzz\FLAG and wtsScer\UAS.T:Hsap\MYC under the control of Scer\GAL4Act5C.PI are not recovered in the wing disc. Clones co-expressing hpoScer\UAS.T:Zzzz\FLAG, ykiS168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1 and wtsScer\UAS.T:Hsap\MYC under the control of Scer\GAL4Act5C.PI are not recovered in the wing disc.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
hpoScer\UAS.T:Zzzz\FLAG
hpoUAS.Tag:FLAG
Name Synonyms
Secondary FlyBase IDs
    References (6)