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General Information
Symbol
Dmel\dgoUAS.cFa
Species
D. melanogaster
Name
FlyBase ID
FBal0152018
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-dgo
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Expression of dgo is under the control of UAS sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Overexpression of dgoScer\UAS.cFa using Scer\GAL4hs.2sev induces ommatidial chirality and rotational defects in the eye and wing hair orientation defects between wing veins L1 and L4.

No wing margin bristle loss is seen when dgoScer\UAS.cFa is expressed under the control of Scer\GAL4en-e16E.

Expression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev results in planar cell polarity defects in the eye, including rotation and chirality defects in the ommatidial clusters.

Expression of dgoScer\UAS.cFa under the control of Scer\GAL4dpp.blk1 in a stripe along the proximo-distal axis of the wing results in a reorientation of wing hairs, which now point laterally away from the expression domain.

Wing hairs adjacent to the ptc expression domain in dgoScer\UAS.cFa; Scer\GAL4ptc-559.1 flies are mis-oriented to point away from the expression domain.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

Scer\GAL4hs.2sev, dgoUAS.cFa has visible phenotype, enhanceable by Vangstbm-6/Vang[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has visible phenotype, enhanceable by VangX/Vang[+]

NOT Enhanced by
Suppressed by
Statement
Reference

Scer\GAL4hs.2sev, dgoUAS.cFa has visible phenotype, suppressible by stan[+]/stanE59

Scer\GAL4hs.2sev, dgoUAS.cFa has visible phenotype, suppressible by stan[+]/stanfrz3

NOT suppressed by
Phenotype Manifest In
Enhanced by
Statement
Reference

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, enhanceable by baz815-8/baz[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, enhanceable by baz4/baz[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, enhanceable by aop443/aop[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, enhanceable by aop[+]/aope2d

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, enhanceable by Dl7/Dl[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, enhanceable by DlRF/Dl[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, enhanceable by VangX/Vang[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, enhanceable by ds38k/ds[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, enhanceable by dsUAO71/ds[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, enhanceable by VangX/Vang[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, enhanceable by Vangstbm-6/Vang[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, enhanceable by Vangstbm-6/Vang[+]

NOT Enhanced by
Statement
Reference

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-enhanceable by baz815-8/baz[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-enhanceable by baz4/baz[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-enhanceable by aop443/aop[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-enhanceable by aop[+]/aope2d

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-enhanceable by Dl7/Dl[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-enhanceable by DlRF/Dl[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-enhanceable by ds38k/ds[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-enhanceable by dsUAO71/ds[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-enhanceable by Df(1)ED447/+

Suppressed by
Statement
Reference

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, suppressible by stan[+]/stanE59

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, suppressible by stan[+]/stan192

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, suppressible by stan[+]/stanfrz3

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, suppressible by stan[+]/stanfrz3

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, suppressible by fz[+]/fz13

Scer\GAL4hs.2sev, dgoUAS.cFa has ommatidium phenotype, suppressible by dsh1/dsh[+]

NOT suppressed by
Statement
Reference

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-suppressible by baz815-8/baz[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-suppressible by baz4/baz[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-suppressible by aop443/aop[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-suppressible by aop[+]/aope2d

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-suppressible by Dl7/Dl[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-suppressible by DlRF/Dl[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-suppressible by ds38k/ds[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-suppressible by dsUAO71/ds[+]

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-suppressible by Df(1)ED447/+

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-suppressible by Df(2L)ED793/+

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-suppressible by Df(1)ED6727/+

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-suppressible by Df(2L)ED775/+

Scer\GAL4hs.2sev, dgoUAS.cFa has wing hair phenotype, non-suppressible by +/Df(3L)ED201

Enhancer of
Other
Additional Comments
Genetic Interactions
Statement
Reference

VangX/+ significantly enhances both the eye and wing defects induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

Vangstbm-6/+ significantly enhances both the eye and wing defects induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

stan192/+ significantly suppresses the eye defects induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

stanfrz3/+ significantly suppresses both the eye and wing defects induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

stanE59/+ significantly suppresses the wing defects induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

baz815-8/+ enhances the planar cell polarity (PCP) defects in the eye induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

baz4/+ enhances the planar cell polarity (PCP) defects in the eye induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

aop443/+ enhances the planar cell polarity (PCP) defects in the eye induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

aope2d/+ enhances the planar cell polarity (PCP) defects in the eye induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

ds38k/+ enhances the ommatidial rotation defects induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

dsUAO71/+ enhances the ommatidial rotation defects induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

Dl7/+ enhances the ommatidial rotation defects induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

DlRF/+ enhances the ommatidial rotation defects induced by the overexpression of dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev.

Mks1GD9100 enhances the planar cell polarity phenotype in the eye induced by overexpression of dgoScer\UAS.cFa using Scer\GAL4hs.2sev.

Df(1)ED7161 dominantly enhances the ommatidial rotation defects induced by Scer\GAL4hs.2sev>dgoScer\UAS.cFa.

Expression of dgoScer\UAS.cFa enhances the wing margin bristle loss seen when fz1-1-1.Scer\UAS.T:Hsap\MYC is expressed under the control of Scer\GAL4en-e16E. 70.8% of wings have a large area lacking margin bristles.

The planar cell polarity defects seen in the eyes of flies expressing dgoScer\UAS.cFa under the control of Scer\GAL4hs.2sev are dominantly suppressed by fz13/+ or dsh1/+ and dominantly enhanced by pkpk-sple-6/+.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
dgoScer\UAS.cFa
dgoUAS.cFa
Name Synonyms
Secondary FlyBase IDs
    References (5)