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General Information
Symbol
Scer\GAL4ppk.1.9
Species
S. cerevisiae
Name
FlyBase ID
FBal0152201
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
ppk-GAL4, ppk1.9-GAL4, ppk1.9GAL4, pickpocket1.9-GAL4
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
An approximately 1.9kb fragment of ppk 5' flanking sequence regulates expression of a GAL4 driver.
Allele components
Product class / Tool use(s)
Regulatory region(s)
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference
Drives expression in multidendritic and some bipolar neurons.
This Gal4 driver which mimicks the expression of the ppk gene is expressed in a single md neuron within the d, v' and v PNS clusters. This construct also drives expression in four bipolar neurons in each of the upper brain lobes.
 
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
dendrite & abdominal anterior ventral multidendritic neuron vdaa, with DebclUAS.Tag:HA
dendrite & abdominal anterior ventral multidendritic neuron vdaa, with prelUAS.Tag:HA
dendrite & class IV dendritic arborising neuron, with DebclUAS.Tag:HA
dendrite & class IV dendritic arborising neuron, with prelUAS.Tag:HA
dendrite & dorsal multidendritic neuron ddaC, with tutlRE40452.UAS
dendrite & dorsal multidendritic neuron ddaC | somatic clone, with DebclUAS.Tag:HA
dendrite & dorsal multidendritic neuron ddaC | somatic clone, with prelUAS.Tag:HA
mitochondrion & dorsal multidendritic neuron ddaC, with DebclUAS.Tag:HA
mitochondrion & dorsal multidendritic neuron ddaC | somatic clone, with prelUAS.Tag:HA
Detailed Description
Statement
Reference
Activating Scer\GAL4ppk.1.9 neurons leads to escape sequences in larvae: a low likelihood of escape rolling behavior and a high likelihood of fast crawling. Mechanosensory (vibration) stimulation alone evokes only fast crawling (no rolling). When both are simultaneous (nociceptive stimulation via activation of Scer\GAL4ppk.1.9 neurons, along with mechanosensory stimulation) significantly increases the likelihood of rolling behavior; this effect is dose-dependent and synergistic. Vibration-induced facilitation of rolling is mediated through mechanosensory chordotonal neurons.
Optogenetic activation (using Crei\ChR2UAS.cSa with 470 nm (blue) light) of Scer\GAL4ppk.1.9 cells in larvae results in a significant increase in escape behaviors, compared to controls.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
NOT suppressed by
Enhancer of
Statement
Reference
Suppressor of
Statement
Reference
NOT Suppressor of
Phenotype Manifest In
Suppressed by
NOT suppressed by
Suppressor of
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Scer\GAL4ppk.1.9
Name Synonyms
Secondary FlyBase IDs
    References (46)