Allele Scer\GAL4^ppk.1.9

General Information
Symbol	Scer\GAL4^ppk.1.9	Species	S. cerevisiae
Name		FlyBase ID	FBal0152201
Feature type	allele	Associated gene	Scer\GAL4

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
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FB2013_03
FB2013_02	Controlled Vocabulary Terms chemical conditional pain response defective behavior defective neurophysiology defective
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Ainsley et al., 2003)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: An approximately 1.9kb fragment of ppk 5' flanking sequence drives expression of Scer\GAL4. (Ainsley et al., 2003)
Carried in construct	P{ppk-GAL4.1.9} (Williams and Truman, 2005, Long et al., 2009, Ainsley et al., 2003, Zhong et al., 2012, Kirilly et al., 2009, Thorne and Amrein, 2008, Diao et al., 2010, Williams et al., 2006, Satoh et al., 2008, Cognigni et al., 2011, Song et al., 2011, Tao and Rolls, 2011, Rossetto et al., 2011, Metzstein and Krasnow, 2006, Stewart et al., 2012, Boiko et al., 2012, Hwang et al., 2007, Tsubouchi et al., 2012)
Cytology
Phenotypic Data
Phenotypic Class
	behavior defective \| third instar larval stage \| chemical conditional, with Crei\ChR2^{Scer\UAS.cHa.T:Avic\GFP-EYFP} (Hwang et al., 2007) decreased cell death, with Sox14^GD4416 (Kirilly et al., 2009) heat stress response defective, with kat-60L1^GD7435 (Stewart et al., 2012) locomotor behavior defective, with ppk^{E145X.Scer\UAS} (Ainsley et al., 2003) locomotor behavior defective \| third instar larval stage, with ppk^{deg.Scer\UAS.T:Zzzz\FLAG} (Boiko et al., 2012) neuroanatomy defective, with BacA\p35^Scer\UAS.cHa (Williams et al., 2006, Tao and Rolls, 2011) neuroanatomy defective, with ik2^KK102408 (Tao and Rolls, 2011) neuroanatomy defective, with kat-60L1^GD7435 (Tao and Rolls, 2011) neuroanatomy defective, with Mical^GD13442 (Tao and Rolls, 2011) neuroanatomy defective, with Mical^Scer\UAS.fl (Kirilly et al., 2009) neuroanatomy defective, with Mmus\wld^S.Scer\UAS (Tao and Rolls, 2011) neuroanatomy defective, with Nc^GD12376 (Tao and Rolls, 2011) neuroanatomy defective, with Nc^{ΔN.C-A.Scer\UAS} (Williams et al., 2006) neuroanatomy defective, with Scer\UBP2^Scer\UAS.cDa (Tao and Rolls, 2011) neuroanatomy defective, with Sox14^fl.Scer\UAS (Kirilly et al., 2009) neuroanatomy defective, with th^Scer\UAS.cHa (Williams et al., 2006, Tao and Rolls, 2011) neuroanatomy defective, with tutl^Scer\UAS.cLa (Long et al., 2009) neuroanatomy defective, with W^Scer\UAS.cZa (Williams et al., 2006) neuroanatomy defective \| somatic clone, with debcl^{Scer\UAS.T:Ivir\HA1} (Tsubouchi et al., 2009) neuroanatomy defective \| somatic clone, with prel^{Scer\UAS.T:Ivir\HA1} (Tsubouchi et al., 2009) neuroanatomy defective \| third instar larval stage, with Efhc1.1^{Scer\UAS.T:Avic\GFP} (Rossetto et al., 2011) neuroanatomy defective \| third instar larval stage, with Rab5^{N142I.Scer\UAS} (Satoh et al., 2008) neurophysiology defective, with ppk^{deg.Scer\UAS.T:Zzzz\FLAG} (Boiko et al., 2012) pain response defective \| third instar larval stage, with Ctet\TeTxLC^TNT.Scer\UAS (Hwang et al., 2007) pain response defective \| third instar larval stage, with ppk^{deg.Scer\UAS.T:Zzzz\FLAG} (Boiko et al., 2012) stress response defective, with Crei\ChR2^{Scer\UAS.cHa.T:Avic\GFP-EYFP} (Stewart et al., 2012) stress response defective, with kat-60L1^GD7435 (Stewart et al., 2012)
Phenotype Manifest In
	axon \| third instar larval stage, with Rab5^{N142I.Scer\UAS} (Satoh et al., 2008) class IV dendritic arborizing neuron, with ppk^{deg.Scer\UAS.T:Zzzz\FLAG} (Boiko et al., 2012) class IV dendritic arborizing neuron, with spas^Scer\UAS.cSa (Stewart et al., 2012) dendrite, with BacA\p35^Scer\UAS.cHa (Williams et al., 2006, Tao and Rolls, 2011) dendrite, with ik2^KK102408 (Tao and Rolls, 2011) dendrite, with kat-60L1^GD7435 (Tao and Rolls, 2011) dendrite, with Mical^GD13442 (Tao and Rolls, 2011) dendrite, with Mical^Scer\UAS.fl (Kirilly et al., 2009) dendrite, with Mmus\wld^S.Scer\UAS (Tao and Rolls, 2011) dendrite, with Nc^GD12376 (Tao and Rolls, 2011) dendrite, with Nc^{ΔN.C-A.Scer\UAS} (Williams et al., 2006) dendrite, with Scer\UBP2^Scer\UAS.cDa (Tao and Rolls, 2011) dendrite, with Sox14^fl.Scer\UAS (Kirilly et al., 2009) dendrite, with Sox14^GD4416 (Kirilly et al., 2009) dendrite, with spas^Scer\UAS.cSa (Stewart et al., 2012) dendrite, with th^Scer\UAS.cHa (Williams et al., 2006, Tao and Rolls, 2011) dendrite, with W^Scer\UAS.cZa (Williams et al., 2006) dendrite & abdominal anterior ventral multidendritic neuron vdaa, with debcl^{Scer\UAS.T:Ivir\HA1} (Tsubouchi et al., 2009) dendrite & abdominal anterior ventral multidendritic neuron vdaa, with prel^{Scer\UAS.T:Ivir\HA1} (Tsubouchi et al., 2009) dendrite & class IV dendritic arborising neuron, with debcl^{Scer\UAS.T:Ivir\HA1} (Tsubouchi et al., 2009) dendrite & class IV dendritic arborising neuron, with prel^{Scer\UAS.T:Ivir\HA1} (Tsubouchi et al., 2009) dendrite & dorsal multidendritic neuron ddaC, with tutl^Scer\UAS.cLa (Long et al., 2009) dendrite & dorsal multidendritic neuron ddaC \| somatic clone, with debcl^{Scer\UAS.T:Ivir\HA1} (Tsubouchi et al., 2009) dendrite & dorsal multidendritic neuron ddaC \| somatic clone, with prel^{Scer\UAS.T:Ivir\HA1} (Tsubouchi et al., 2009) dendrite \| third instar larval stage, with Rab5^{N142I.Scer\UAS} (Satoh et al., 2008) dendritic arborizing neuron \| third instar larval stage, with Efhc1.1^{Scer\UAS.T:Avic\GFP} (Rossetto et al., 2011) dorsal multidendritic neuron ddaC, with BacA\p35^Scer\UAS.cHa (Williams et al., 2006, Tao and Rolls, 2011) dorsal multidendritic neuron ddaC, with ik2^KK102408 (Tao and Rolls, 2011) dorsal multidendritic neuron ddaC, with kat-60L1^GD7435 (Tao and Rolls, 2011) dorsal multidendritic neuron ddaC, with Mical^GD13442 (Tao and Rolls, 2011) dorsal multidendritic neuron ddaC, with Mical^Scer\UAS.fl (Kirilly et al., 2009) dorsal multidendritic neuron ddaC, with Mmus\wld^S.Scer\UAS (Tao and Rolls, 2011) dorsal multidendritic neuron ddaC, with Nc^GD12376 (Tao and Rolls, 2011) dorsal multidendritic neuron ddaC, with Nc^{ΔN.C-A.Scer\UAS} (Williams et al., 2006) dorsal multidendritic neuron ddaC, with Scer\UBP2^Scer\UAS.cDa (Tao and Rolls, 2011) dorsal multidendritic neuron ddaC, with Sox14^fl.Scer\UAS (Kirilly et al., 2009) dorsal multidendritic neuron ddaC, with Sox14^GD4416 (Kirilly et al., 2009) dorsal multidendritic neuron ddaC, with th^Scer\UAS.cHa (Williams et al., 2006, Tao and Rolls, 2011) dorsal multidendritic neuron ddaC, with W^Scer\UAS.cZa (Williams et al., 2006) microtubule, with spas^Scer\UAS.cSa (Stewart et al., 2012) mitochondrion & dorsal multidendritic neuron ddaC, with debcl^{Scer\UAS.T:Ivir\HA1} (Tsubouchi et al., 2009) mitochondrion & dorsal multidendritic neuron ddaC \| somatic clone, with prel^{Scer\UAS.T:Ivir\HA1} (Tsubouchi et al., 2009)
Detailed Description
	Statement Reference
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement Reference Crei\ChR2^{Scer\UAS.cHa.T:Avic\GFP-EYFP}, Scer\GAL4^ppk.1.9 has stress response defective phenotype, suppressible by para^GD3392, Scer\GAL4^ppk.1.9 (Stewart et al., 2012, Stewart et al., 2012) Crei\ChR2^{Scer\UAS.cHa.T:Avic\GFP-EYFP}, Scer\GAL4^ppk.1.9 has stress response defective phenotype, suppressible by spas[+]/spas^5.75 (Stewart et al., 2012) Crei\ChR2^{Scer\UAS.cHa.T:Avic\GFP-EYFP}, Scer\GAL4^ppk.1.9 has stress response defective phenotype, suppressible by spas^KK107786, Scer\GAL4^ppk.1.9 (Stewart et al., 2012, Stewart et al., 2012) Scer\GAL4^ppk.1.9, debcl^{Scer\UAS.T:Ivir\HA1} has neuroanatomy defective \| somatic clone phenotype, suppressible by Buffy^Scer\UAS.cQa, Scer\GAL4^ppk.1.9 (Tsubouchi et al., 2009, Tsubouchi et al., 2009) Scer\GAL4^ppk.1.9, Sox14^fl.Scer\UAS has neuroanatomy defective phenotype, suppressible by Mical¹⁵²⁵⁶ (Kirilly et al., 2009)
NOT suppressed by
Statement Reference Crei\ChR2^{Scer\UAS.cHa.T:Avic\GFP-EYFP}, Scer\GAL4^ppk.1.9 has stress response defective phenotype, non-suppressible by kat-60L1^GD7435, Scer\GAL4^ppk.1.9 (Stewart et al., 2012, Stewart et al., 2012)
Suppressor of
Statement Reference Buffy^Scer\UAS.cQa, Scer\GAL4^ppk.1.9 is a suppressor of neuroanatomy defective \| somatic clone phenotype of Scer\GAL4^ppk.1.9, debcl^{Scer\UAS.T:Ivir\HA1} (Tsubouchi et al., 2009, Tsubouchi et al., 2009) Buffy^Scer\UAS.cQa/Scer\GAL4^ppk.1.9 is a suppressor of neuroanatomy defective \| somatic clone phenotype of prel¹ (Tsubouchi et al., 2009) fra^Scer\UAS.cKa/Scer\GAL4^ppk.1.9 is a suppressor of neuroanatomy defective phenotype of Trim9⁴⁶ (Song et al., 2011) para^GD3392, Scer\GAL4^ppk.1.9 is a suppressor of stress response defective phenotype of Crei\ChR2^{Scer\UAS.cHa.T:Avic\GFP-EYFP}, Scer\GAL4^ppk.1.9 (Stewart et al., 2012, Stewart et al., 2012) Sox14^fl.Scer\UAS/Scer\GAL4^ppk.1.9 is a suppressor \| partially of neuroanatomy defective phenotype of Mical¹⁵²⁵⁶ (Kirilly et al., 2009) spas^KK107786, Scer\GAL4^ppk.1.9 is a suppressor of stress response defective phenotype of Crei\ChR2^{Scer\UAS.cHa.T:Avic\GFP-EYFP}, Scer\GAL4^ppk.1.9 (Stewart et al., 2012, Stewart et al., 2012)
NOT Suppressor of
Statement Reference kat-60L1^GD7435, Scer\GAL4^ppk.1.9 is a non-suppressor of stress response defective phenotype of Crei\ChR2^{Scer\UAS.cHa.T:Avic\GFP-EYFP}, Scer\GAL4^ppk.1.9 (Stewart et al., 2012, Stewart et al., 2012)
Phenotype Manifest In
Suppressed by
Statement Reference Scer\GAL4^ppk.1.9, debcl^{Scer\UAS.T:Ivir\HA1} has dorsal multidendritic neuron ddaC \| somatic clone phenotype, suppressible by Buffy^Scer\UAS.cQa, Scer\GAL4^ppk.1.9 (Tsubouchi et al., 2009, Tsubouchi et al., 2009) Scer\GAL4^ppk.1.9, debcl^{Scer\UAS.T:Ivir\HA1} has mitochondrion & dorsal multidendritic neuron ddaC phenotype, suppressible by Buffy^Scer\UAS.cQa, Scer\GAL4^ppk.1.9 (Tsubouchi et al., 2009, Tsubouchi et al., 2009) Scer\GAL4^ppk.1.9, Sox14^fl.Scer\UAS has dendrite phenotype, suppressible by Mical¹⁵²⁵⁶ (Kirilly et al., 2009) Scer\GAL4^ppk.1.9, Sox14^fl.Scer\UAS has dorsal multidendritic neuron ddaC phenotype, suppressible by Mical¹⁵²⁵⁶ (Kirilly et al., 2009)
Suppressor of
Statement Reference Buffy^Scer\UAS.cQa, Scer\GAL4^ppk.1.9 is a suppressor of dorsal multidendritic neuron ddaC \| somatic clone phenotype of Scer\GAL4^ppk.1.9, debcl^{Scer\UAS.T:Ivir\HA1} (Tsubouchi et al., 2009, Tsubouchi et al., 2009) Buffy^Scer\UAS.cQa, Scer\GAL4^ppk.1.9 is a suppressor of mitochondrion & dorsal multidendritic neuron ddaC phenotype of Scer\GAL4^ppk.1.9, debcl^{Scer\UAS.T:Ivir\HA1} (Tsubouchi et al., 2009, Tsubouchi et al., 2009) Buffy^Scer\UAS.cQa/Scer\GAL4^ppk.1.9 is a suppressor of dendrite & dorsal multidendritic neuron ddaC \| somatic clone phenotype of prel¹ (Tsubouchi et al., 2009) fra^Scer\UAS.cKa/Scer\GAL4^ppk.1.9 is a suppressor of dopaminergic neuron phenotype of Trim9⁴⁶ (Song et al., 2011) fra^Scer\UAS.cKa/Scer\GAL4^ppk.1.9 is a suppressor of midline crossing tract phenotype of Trim9⁴⁶ (Song et al., 2011) Sox14^fl.Scer\UAS/Scer\GAL4^ppk.1.9 is a suppressor \| partially of dendrite phenotype of Mical¹⁵²⁵⁶ (Kirilly et al., 2009) Sox14^fl.Scer\UAS/Scer\GAL4^ppk.1.9 is a suppressor \| partially of dorsal multidendritic neuron ddaC phenotype of Mical¹⁵²⁵⁶ (Kirilly et al., 2009)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	ppk^Scer\UAS.cAa/Scer\GAL4^ppk.1.9 rescues Df(2L)A400/Df(2L)b88h49 (Ainsley et al., 2003) Scer\GAL4^ppk.1.9/Mical^Scer\UAS.fl rescues Mical¹⁵²⁵⁶ (Kirilly et al., 2009) Scer\GAL4^ppk.1.9/Mical^Scer\UAS.fl rescues Mical¹⁵²⁵⁶/Df(3R)swp2^MICAL (Kirilly et al., 2009) Scer\GAL4^ppk.1.9/ppk^{Scer\UAS.T:Zzzz\FLAG} rescues ppk^ESB (Boiko et al., 2012) Trim9^Scer\UAS.cSa/Scer\GAL4^ppk.1.9 rescues Trim9⁴⁶ (Song et al., 2011) TrpA1^C.Scer\UAS/Scer\GAL4^ppk.1.9 rescues TrpA1^W903 (Zhong et al., 2012)
Fails to rescue	Mical^{N-ter.Scer\UAS}/Scer\GAL4^ppk.1.9 fails to rescue Mical¹⁵²⁵⁶ (Kirilly et al., 2009) Mical^{N-ter.Scer\UAS}/Scer\GAL4^ppk.1.9 fails to rescue Mical¹⁵²⁵⁶/Df(3R)swp2^MICAL (Kirilly et al., 2009)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Gal4^ppk (Tsubouchi et al., 2009) Scer\GAL4^ppk.1.9
Name Synonym
Secondary FlyBase IDs

References ( 19 )
Research paper	Boiko et al., 2012, J. Biol. Chem. 287(47): 39878--39886 Pickpocket1 is an ionotropic molecular sensory transducer. [FBrf0219990] Stewart et al., 2012, J. Neurosci. 32(34): 11631--11642 Katanin p60-like1 Promotes Microtubule Growth and Terminal Dendrite Stability in the Larval Class IV Sensory Neurons of Drosophila. [FBrf0219283] Tsubouchi et al., 2012, Curr. Biol. 22(22): 2124--2134 Dendritic Filopodia, Ripped Pocket, NOMPC, and NMDARs Contribute to the Sense of Touch in Drosophila Larvae. [FBrf0219946] Zhong et al., 2012, Cell Rep. 1(1): 43--55 Thermosensory and non-thermosensory isoforms of Drosophila melanogaster TRPA1 reveal heat sensor domains of a thermoTRP channel. [FBrf0217493] Cognigni et al., 2011, Cell Metab. 13(1): 92--104 Enteric neurons and systemic signals couple nutritional and reproductive status with intestinal homeostasis. [FBrf0212594] Rossetto et al., 2011, Hum. Mol. Genet. 20(21): 4248--4257 Defhc1.1, a homologue of the juvenile myoclonic gene EFHC1, modulates architecture and basal activity of the neuromuscular junction in Drosophila. [FBrf0216330] Song et al., 2011, J. Genet. Genomics 38(1): 1--11 TRIM-9 functions in the UNC-6/UNC-40 pathway to regulate ventral guidance. [FBrf0213082] Tao and Rolls, 2011, J. Neurosci. 31(14): 5398--5405 Dendrites have a rapid program of injury-induced degeneration that is molecularly distinct from developmental pruning. [FBrf0213404] Diao et al., 2010, Mol. Cell. Neurosci. 45(1): 75--83 SIDL interacts with the dendritic targeting motif of Shal (K(v)4) K(+) channels in Drosophila. [FBrf0211355] Kirilly et al., 2009, Nat. Neurosci. 12(12): 1497--1505 A genetic pathway composed of Sox14 and Mical governs severing of dendrites during pruning. [FBrf0209365] Long et al., 2009, Development 136(20): 3475--3484 Dendrite branching and self-avoidance are controlled by Turtle, a conserved IgSF protein in Drosophila. [FBrf0208798] Tsubouchi et al., 2009, Development 136(22): 3757--3766 Mitochondrial protein Preli-like is required for development of dendritic arbors and prevents their regression in the Drosophila sensory nervous system. [FBrf0209126] Satoh et al., 2008, Nat. Cell Biol. 10(10): 1164--1171 Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes. [FBrf0207048] Thorne and Amrein, 2008, J. Comp. Neurol. 506(4): 548--568 Atypical expression of Drosophila gustatory receptor genes in sensory and central neurons. [FBrf0201488] Hwang et al., 2007, Curr. Biol. 17(24): 2105--2116 Nociceptive neurons protect Drosophila larvae from parasitoid wasps. [FBrf0200914] Metzstein and Krasnow, 2006, PLoS Genet. 2(12): e180 Functions of the nonsense-mediated mRNA decay pathway in Drosophila development. [FBrf0194265] Williams et al., 2006, Nat. Neurosci. 9(10): 1234--1236 Local caspase activity directs engulfment of dendrites during pruning. [FBrf0192062] Williams and Truman, 2005, Development 132(16): 3631--3642 Cellular mechanisms of dendrite pruning in Drosophila: insights from in vivo time-lapse of remodeling dendritic arborizing sensory neurons. [FBrf0187491] Ainsley et al., 2003, Curr. Biol. 13(17): 1557--1563 Enhanced locomotion caused by loss of the Drosophila DEG/ENaC protein Pickpocket1. [FBrf0162002]

Allele Scer\GAL4ppk.1.9

Allele Scer\GAL4^ppk.1.9