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General Information
Symbol
Dmel\Ptp69D7
Species
D. melanogaster
Name
FlyBase ID
FBal0152273
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:

Reported as a 9bp deletion that removes amino acid residues 1065-1067. Position of mutation on reference sequence inferred by FlyBase curator.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

9bp deletion, deleting amino acids 1065-1067.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes do not form pupae at either 18 or 25oC. Ptp69D7 embryos show motor axon defects; 57% of ISNb axons, 27% of ISN axons, 24% of SNa axons and 26% of SNc axons show defects. 25% of ISNb axons show a complete bypass phenotype and 15% show a partial bypass phenotype.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference

Ptp69D7 has neuroanatomy defective phenotype, suppressible by Ptp99A[+]/Ptp99A1

NOT Enhancer of
Statement
Reference

Ptp69D[+]/Ptp69D7 is a non-enhancer of neuroanatomy defective | embryonic stage phenotype of cknK.Δ324-331

NOT Suppressor of
Statement
Reference

Ptp69D[+]/Ptp69D7 is a non-suppressor of neuroanatomy defective | embryonic stage phenotype of cknK.Δ324-331

Phenotype Manifest In
Suppressed by
Statement
Reference

Ptp69D7 has intersegmental nerve phenotype, suppressible by Ptp99A[+]/Ptp99A1

NOT Enhancer of
Statement
Reference
NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

A heterozygous or homozygous Ptp69D7 background fails to affect the penetrance of the ISNb bypass phenotype found in cknK.Δ324-331 heterozygotes or homozygotes.

The ISNb bypass phenotype seen in Ptp69D7 homozygous embryos is largely suppressed by one copy of Ptp99A1.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)