FlyBase Allele Report: Dmel\Mkp3[UAS.cRa]

General Information

Symbol

Dmel\Mkp3^UAS.cRa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Rintelen

FlyBase ID

FBal0152416

Feature type

allele

Associated gene

Dmel\Mkp3

Associated Insertion(s)

Carried in Construct

P{UAS-Mkp3.R}

Key Links

Transgenic product class

cDNA

(Rintelen et al., 2003)

wild_type

(Rintelen et al., 2003)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Rintelen et al., 2003)

wild_type

(Rintelen et al., 2003)

Mutagen

in vitro construct

(Rintelen et al., 2003)

Progenitor genotype

Carried in construct

P{UAS-Mkp3.R}

Cytology

Description

UASt regulatory sequences drive expression of the Mkp3 SD06439 cDNA.

(Rintelen et al., 2003)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Mkp3

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^en-GAL4-33

(Rintelen et al., 2003)

Phenotype Manifest In

photoreceptor cell R3, with Scer\GAL4^hs.2sev

(Rintelen et al., 2003)

photoreceptor cell R4, with Scer\GAL4^hs.2sev

(Rintelen et al., 2003)

photoreceptor neuron, with Scer\GAL4^hs.2sev

(Rintelen et al., 2003)

wing vein, with Scer\GAL4^en-GAL4-33

(Rintelen et al., 2003)

Detailed Description

Statement

Reference

Expression of Mkp3^Scer\UAS.cRa under the control of Scer\GAL4^hs.2sev partially inhibits photoreceptor formation, mostly affecting the R3/R4 pair. Expression of Mkp3^Scer\UAS.cRa under the control of Scer\GAL4^en-GAL4-33 partially inhibits vein formation. Expression of Mkp3^Scer\UAS.cRa under the control of Scer\GAL4^69B does not affect dorsal closure in the embryo.

(Rintelen et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT Suppressor of

Statement

Reference

Scer\GAL4^en-GAL4-33/Mkp3^UAS.cRa is a non-suppressor of wing vein | increased number phenotype of rl^Sem

(Rintelen et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

The rl^Sem extra wing vein phenotype is unaffected by the expression of Mkp3^Scer\UAS.cRa under the control of Scer\GAL4^en-GAL4-33.

(Rintelen et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Mkp3^Scer\UAS.cRa

Mkp3^UAS.cRa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Rintelen

(Rintelen et al., 2003)

Secondary FlyBase IDs

References (1)

Report Sections

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