FB2025_02 , released April 17, 2025
Allele: Dmel\Mkp34
Open Close
General Information
Symbol
Dmel\Mkp34
Species
D. melanogaster
Name
FlyBase ID
FBal0152423
Feature type
allele
Associated gene
Dmel\Mkp3
Associated Insertion(s)
P{EP}Mkp34
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Rintelen et al., 2003)
Mutagen
Delta2-3 transposase
(Rintelen et al., 2003)
Progenitor genotype
P{EP}MESR6EP3142
(Rintelen et al., 2003)
Associated Insertion(s)
P{EP}Mkp34
Cytology
Description

Mobilisation of the P{EP}MESR6EP3142 element, resulting in a P{EP} insertion in the 5' UTR of Mkp3, 483bp upstream of the Mkp3 ATG codon, with the P{EP} element inserted such that overexpression from the P{EP} element results in overexpression of Mkp3. The progenitor P{EP}MESR6EP3142 insertion is also still present on the chromosome.

(Rintelen et al., 2003)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of Mkp34 under the control of Scer\GAL4hs.2sev results in a rough eye phenotype.

      (Rintelen et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dmkp34
      (Rintelen et al., 2003)
      Mkp34
      Name Synonyms
      Secondary FlyBase IDs
        References (1)